1z9w

Tetrameric structure of apo-7,8-Dihydroneopterin Aldolase from Mycobacterium tuberculosis

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Dihydroneopterin aldolase

Mycobacterium tuberculosis H37Rv

UniProt P0A580

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 4 water × 4 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name FOLB_MYCTU
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–133; UniProt 1–133

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id1z9w
Deposition date deposition_date2005-04-05
Structure title titleTetrameric structure of apo-7,8-Dihydroneopterin Aldolase from Mycobacterium tuberculosis
Keywords keywords;FOLB, MYCOBACTERIUM TUBERCULOSIS, Structural Genomics, TB Structural Genomics, Mycobacterium Tuberculosis Structural Proteomics Project, XMTB, PSI, Protein Structure Initiative, LYASE ;; LYASE
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1z9w__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1z9w__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1z9w__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)24.55 Å
Rg (electron density)23.21 Å
Total Rg24.14 Å
Atom count3284
Residues432
Excluded volume57662 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1z9w__assembly_1__model_1 tetrameric (4) Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (2)

▼

6. Fold Classification (SCOP + CATH) 2 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd1z9wa_
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.96 — T-fold
Superfamily Superfamily superfamilyd.96.1 — Tetrahydrobiopterin biosynthesis enzymes-like
Family Family familyd.96.1.3 — DHN aldolase/epimerase

CATH v4.4 (1 domains)

Domain ID domain_id1z9wA00
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1130 — GTP Cyclohydrolase I, domain 2
Homologous superfamily homologous superfamily10 — GTP cyclohydrolase I, C-terminal domain/NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal domain
▶

7. Citations (1)