1zhs

Crystal structure of MVL bound to Man3GlcNAc2

Method: X-RAY DIFFRACTION

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1. Protein Identity and Related Structures Protein Identity & Related Structures

No usable UniProt protein identity is available for this entry.

The relationship tables retain this entry's assembly and composition data, but cross-PDB links for the same protein cannot be established reliably without a unified protein identity.

Assembly Composition of the Current Entry

Assembly	Physical composition	Protein state	蛋白 / DNA / RNA / 其他Polymer	Data consistency
1	Other combination	Homooligomer	2 / 0 / 0 / 4	Consistent with protein count
2	Other combination	Homooligomer	2 / 0 / 0 / 4	Consistent with protein count
3	Other combination	Homooligomer	2 / 0 / 0 / 4	Consistent with protein count
4	Other combination	Homooligomer	2 / 0 / 0 / 4	Consistent with protein count

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	1zhs
Deposition date deposition_date	2005-04-26
Structure title title	Crystal structure of MVL bound to Man3GlcNAc2
Keywords keywords	MVL, HIV-1, carbohydrate binding, SUGAR BINDING PROTEIN; SUGAR BINDING PROTEIN
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1zhs__assembly_4__model_1

Assembly 4 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1zhs__assembly_4__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

1zhs__assembly_4__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	18.88 Å
Rg (electron density)	17.71 Å
Total Rg	18.72 Å
Atom count	2015
Residues	226
Excluded volume	35869 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`1zhs__assembly_1__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`1zhs__assembly_2__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	1	`1zhs__assembly_3__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	1	`1zhs__assembly_4__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

Entity 1 Entity 1 polymer

Description description	mannan-binding lectin
Molecular weight formula_weight	12244.7 kDa
Source method src_method	man
Copy count entity_count	8

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D,E,F,G,H
Atom count atom_count	8669

ASYKVNIPAGPLWSNAEAQQVGPKIAAAHQGNFTGQWTTVVESAMSVVEVELQVENTGIHEFKTDVLAGPLWSNDEAQKLGPQIAASYGAEFTGQWRTIVEGVMSVIQIKYTF

Source Source

Source organism organism	Microcystis viridis
NCBI taxonomy ID ncbi_taxonomy_id	44822
Host organism host_organism	Escherichia coli

Entity 2 Entity 2 branched

Description description	;alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ;
Molecular weight formula_weight	910.8 kDa
Source method src_method	man
Copy count entity_count	16

Entity 3 Entity 3 non-polymer

Description description	1,2-ETHANEDIOL
Molecular weight formula_weight	62.1 kDa
Source method src_method	syn
Copy count entity_count	26

Entity 4 Entity 4 non-polymer

Description description	PHOSPHATE ION
Molecular weight formula_weight	95.0 kDa
Source method src_method	syn
Copy count entity_count	2

Entity 5 Entity 5 water

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	643

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6. Fold Classification (SCOP + CATH) 32 domains

SCOP 2.08 (16 domains)

Domain ID domain_id	d1zhsa1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.230 — Dodecin subunit-like
Superfamily Superfamily superfamily	d.230.7 — Oligosaccharide binding protein
Family Family family	d.230.7.1 — Oligomannose binding protein MVL-like

Domain ID domain_id	d1zhsa2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.230 — Dodecin subunit-like
Superfamily Superfamily superfamily	d.230.7 — Oligosaccharide binding protein
Family Family family	d.230.7.1 — Oligomannose binding protein MVL-like

Domain ID domain_id	d1zhsb1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.230 — Dodecin subunit-like
Superfamily Superfamily superfamily	d.230.7 — Oligosaccharide binding protein
Family Family family	d.230.7.1 — Oligomannose binding protein MVL-like

Domain ID domain_id	d1zhsb2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.230 — Dodecin subunit-like
Superfamily Superfamily superfamily	d.230.7 — Oligosaccharide binding protein
Family Family family	d.230.7.1 — Oligomannose binding protein MVL-like

Domain ID domain_id	d1zhsc1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.230 — Dodecin subunit-like
Superfamily Superfamily superfamily	d.230.7 — Oligosaccharide binding protein
Family Family family	d.230.7.1 — Oligomannose binding protein MVL-like

Domain ID domain_id	d1zhsc2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.230 — Dodecin subunit-like
Superfamily Superfamily superfamily	d.230.7 — Oligosaccharide binding protein
Family Family family	d.230.7.1 — Oligomannose binding protein MVL-like

Domain ID domain_id	d1zhsd1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.230 — Dodecin subunit-like
Superfamily Superfamily superfamily	d.230.7 — Oligosaccharide binding protein
Family Family family	d.230.7.1 — Oligomannose binding protein MVL-like

Domain ID domain_id	d1zhsd2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.230 — Dodecin subunit-like
Superfamily Superfamily superfamily	d.230.7 — Oligosaccharide binding protein
Family Family family	d.230.7.1 — Oligomannose binding protein MVL-like

Domain ID domain_id	d1zhse1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.230 — Dodecin subunit-like
Superfamily Superfamily superfamily	d.230.7 — Oligosaccharide binding protein
Family Family family	d.230.7.1 — Oligomannose binding protein MVL-like

Domain ID domain_id	d1zhse2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.230 — Dodecin subunit-like
Superfamily Superfamily superfamily	d.230.7 — Oligosaccharide binding protein
Family Family family	d.230.7.1 — Oligomannose binding protein MVL-like

Domain ID domain_id	d1zhsf1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.230 — Dodecin subunit-like
Superfamily Superfamily superfamily	d.230.7 — Oligosaccharide binding protein
Family Family family	d.230.7.1 — Oligomannose binding protein MVL-like

Domain ID domain_id	d1zhsf2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.230 — Dodecin subunit-like
Superfamily Superfamily superfamily	d.230.7 — Oligosaccharide binding protein
Family Family family	d.230.7.1 — Oligomannose binding protein MVL-like

Domain ID domain_id	d1zhsg1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.230 — Dodecin subunit-like
Superfamily Superfamily superfamily	d.230.7 — Oligosaccharide binding protein
Family Family family	d.230.7.1 — Oligomannose binding protein MVL-like

Domain ID domain_id	d1zhsg2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.230 — Dodecin subunit-like
Superfamily Superfamily superfamily	d.230.7 — Oligosaccharide binding protein
Family Family family	d.230.7.1 — Oligomannose binding protein MVL-like

Domain ID domain_id	d1zhsh1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.230 — Dodecin subunit-like
Superfamily Superfamily superfamily	d.230.7 — Oligosaccharide binding protein
Family Family family	d.230.7.1 — Oligomannose binding protein MVL-like

Domain ID domain_id	d1zhsh2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.230 — Dodecin subunit-like
Superfamily Superfamily superfamily	d.230.7 — Oligosaccharide binding protein
Family Family family	d.230.7.1 — Oligomannose binding protein MVL-like

CATH v4.4 (16 domains)

Domain ID domain_id	1zhsA01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	230 —

Domain ID domain_id	1zhsA02
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	230 —

Domain ID domain_id	1zhsB01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	230 —

Domain ID domain_id	1zhsB02
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	230 —

Domain ID domain_id	1zhsC01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	230 —

Domain ID domain_id	1zhsC02
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	230 —

Domain ID domain_id	1zhsD01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	230 —

Domain ID domain_id	1zhsD02
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	230 —

Domain ID domain_id	1zhsE01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	230 —

Domain ID domain_id	1zhsE02
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	230 —

Domain ID domain_id	1zhsF01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	230 —

Domain ID domain_id	1zhsF02
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	230 —

Domain ID domain_id	1zhsG01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	230 —

Domain ID domain_id	1zhsG02
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	230 —

Domain ID domain_id	1zhsH01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	230 —

Domain ID domain_id	1zhsH02
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	230 —

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Unit-cell length a length_a	47.783 Å
Unit-cell length b length_b	73.740 Å
Unit-cell length c length_c	78.863 Å
Unit-cell angle α angle_alpha	90.45 °
Unit-cell angle β angle_beta	98.45 °
Unit-cell angle γ angle_gamma	108.91 °
Molecules per unit cell Z z_pdb	8

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	—

Resolution resolution	1.800 Å
Low-resolution limit resolution_low	19.880 Å
R factor r_factor	—
R_work r_work	0.1920
R_free r_free	0.2210