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2aq6

X-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 1.7 a resolution

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

;PYRIDOXINE 5'-PHOSPHATE OXIDASE ;

Mycobacterium tuberculosis

UniProt O06553

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 2 PYRIDOXAL-5'-PHOSPHATE × 1 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer
1w9a 1xxo 1y30 2aq6

4 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex

None

View Construct and Data Evidence
UniProt name O06553_MYCTU
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–147； UniProt 5–151 Author chain B； PDBConstruct 1–147； UniProt 5–151

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2aq6
Deposition date deposition_date2005-08-17
Structure title titleX-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 1.7 a resolution
Keywords keywords;PYRIDOXINE 5'-PHOSPHATE OXIDASE, PYRIDOXAL 5'-PHOSPHATE, Structural Genomics, PSI, Protein Structure Initiative, TB Structural Genomics Consortium, TBSGC, OXIDOREDUCTASE ;; OXIDOREDUCTASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2aq6__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2aq6__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2aq6__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）21.69 Å
Rg (electron density)20.52 Å
Total Rg21.31 Å
Atom count2248
Residues286
Excluded volume39733 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2aq6__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd2aq6a_
Class classb — All beta proteins
Fold Fold foldb.45 — Split barrel-like
Superfamily Superfamily superfamilyb.45.1 — FMN-binding split barrel
Family Family familyb.45.1.1 — PNP-oxidase like
Domain ID domain_idd2aq6b_
Class classb — All beta proteins
Fold Fold foldb.45 — Split barrel-like
Superfamily Superfamily superfamilyb.45.1 — FMN-binding split barrel
Family Family familyb.45.1.1 — PNP-oxidase like

CATH v4.4 (2 domains)

Domain ID domain_id2aq6A00
Class class2 — Mainly Beta
Architecture architecture30 — Roll
Topology topology110 — Pnp Oxidase; Chain A
Homologous superfamily homologous superfamily10 — Electron Transport, Fmn-binding Protein; Chain A
Domain ID domain_id2aq6B00
Class class2 — Mainly Beta
Architecture architecture30 — Roll
Topology topology110 — Pnp Oxidase; Chain A
Homologous superfamily homologous superfamily10 — Electron Transport, Fmn-binding Protein; Chain A
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7. Citations (1)