2f1b
GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH (2R,3R,4S,5R)-2-({[(1R)-2-hydroxy-1-phenylethyl]amino}methyl)-5-methylpyrrolidine-3,4-diol
1. Protein Identity and Related Structures Protein Identity & Related Structures
No usable UniProt protein identity is available for this entry.
The relationship tables retain this entry's assembly and composition data, but cross-PDB links for the same protein cannot be established reliably without a unified protein identity.
Assembly Composition of the Current Entry
| Assembly | Physical composition | Protein state | 蛋白 / DNA / RNA / 其他Polymer | Data consistency |
|---|---|---|---|---|
| 1 | Protein monomer | Monomer | 1 / 0 / 0 / 0 | Consistent with protein count |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
2. Structure Basics 2. Structure Basics
| Entry ID entry_id | 2f1b |
| Deposition date deposition_date | 2005-11-14 |
| Structure title title | GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH (2R,3R,4S,5R)-2-({[(1R)-2-hydroxy-1-phenylethyl]amino}methyl)-5-methylpyrrolidine-3,4-diol |
| Keywords keywords | GLYCOSYL HYDROLASE FAMILY 38, Hydrolase; HYDROLASE |
| Experimental Method method | X-RAY DIFFRACTION |
3. Official assembly/model SAXS Official SAXS Profiles
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
2f1b__assembly_1__model_1
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
2f1b__assembly_1__model_1 | I(q)
2f1b__assembly_1__model_1 | P(r) · Pending
| Rg（Guinier） | 30.77 Å |
| Rg (electron density) | 29.90 Å |
| Total Rg | 30.59 Å |
| Atom count | 8223 |
| Residues | 1014 |
| Excluded volume | 145690 ų |
| Maximum q | 0.500 Å⁻¹ |
4. Crystallography and Experiment 4. Crystallography & Experiment
5. Entities and Polymers Entities & Polymers (6)
6. Fold Classification (SCOP + CATH) 8 domains
SCOP 2.08 (3 domains)
| Domain ID domain_id | d2f1ba1 |
| Class class | a — All alpha proteins |
| Fold Fold fold | a.8 — immunoglobulin/albumin-binding domain-like |
| Superfamily Superfamily superfamily | a.8.3 — Families 57/38 glycoside transferase middle domain |
| Family Family family | a.8.3.1 — alpha-mannosidase, domain 2 |
| Domain ID domain_id | d2f1ba2 |
| Class class | b — All beta proteins |
| Fold Fold fold | b.30 — Supersandwich |
| Superfamily Superfamily superfamily | b.30.5 — Galactose mutarotase-like |
| Family Family family | b.30.5.6 — alpha-mannosidase, C-terminal domain |
| Domain ID domain_id | d2f1ba3 |
| Class class | c — Alpha and beta proteins (a/b) |
| Fold Fold fold | c.6 — 7-stranded beta/alpha barrel |
| Superfamily Superfamily superfamily | c.6.2 — Glycoside hydrolase/deacetylase |
| Family Family family | c.6.2.1 — alpha-mannosidase |
CATH v4.4 (5 domains)
| Domain ID domain_id | 2f1bA01 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 20 — Alpha-Beta Barrel |
| Topology topology | 110 — 7-stranded beta/alpha barrel |
| Homologous superfamily homologous superfamily | 10 — Glycoside hydrolase 38, N terminal domain |
| Domain ID domain_id | 2f1bA02 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 20 — Up-down Bundle |
| Topology topology | 1270 — Substrate Binding Domain Of Dnak; Chain:A; Domain 2 |
| Homologous superfamily homologous superfamily | 50 — Glycoside hydrolase family 38, central domain |
| Domain ID domain_id | 2f1bA03 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 60 — Sandwich |
| Topology topology | 40 — Immunoglobulin-like |
| Homologous superfamily homologous superfamily | 1180 — Golgi alpha-mannosidase II |
| Domain ID domain_id | 2f1bA04 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 70 — Distorted Sandwich |
| Topology topology | 98 — Beta-galactosidase; Chain A, domain 5 |
| Homologous superfamily homologous superfamily | 30 — Golgi alpha-mannosidase II; domain 4 |
| Domain ID domain_id | 2f1bA05 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 60 — Sandwich |
| Topology topology | 40 — Immunoglobulin-like |
| Homologous superfamily homologous superfamily | 1360 — |