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2hdc

STRUCTURE OF TRANSCRIPTION FACTOR GENESIS/DNA COMPLEX

Method: SOLUTION NMR
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1. Protein Identity and Related Structures Protein Identity & Related Structures

PROTEIN (TRANSCRIPTION FACTOR)

Rattus norvegicus

UniProt Q63245

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Monomer Protein 1 DNA 2 ;DNA (5'-D(P*GP*CP*TP*TP*AP*AP*AP*AP*TP*AP*AP*CP*AP*AP*TP*AP*C)-3') ; × 1 ;DNA (5'-D(P*GP*TP*AP*TP*TP*GP*TP*TP*AP*TP*TP*TP*TP*AP*AP*GP*C)-3') ; × 1 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer
2hfh

1 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2hdc

1 assemblies

View Construct and Data Evidence
UniProt name FOXD3_RAT
Isoform —
PDB entities 3
Chains and sequence ranges Author chain A； PDBConstruct 1–97； UniProt 2–98

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2hdc
Deposition date deposition_date1999-05-05
Structure title titleSTRUCTURE OF TRANSCRIPTION FACTOR GENESIS/DNA COMPLEX
Keywords keywordsDYANAMICS, GENESIS, WINGED HELIX PROTEIN, PROTEIN-DNA COMPLEX; PROTEIN/DNA
Experimental Method methodSOLUTION NMR
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2hdc__assembly_1__model_20

Assembly 1 · Model 20 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2hdc__assembly_1__model_20 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2hdc__assembly_1__model_20 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）18.74 Å
Rg (electron density)17.61 Å
Total Rg18.51 Å
Atom count2581
Residues131
Excluded volume24581 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2hdc__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 2 2hdc__assembly_1__model_2 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 3 2hdc__assembly_1__model_3 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 4 2hdc__assembly_1__model_4 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 5 2hdc__assembly_1__model_5 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 6 2hdc__assembly_1__model_6 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 7 2hdc__assembly_1__model_7 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 8 2hdc__assembly_1__model_8 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 9 2hdc__assembly_1__model_9 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 10 2hdc__assembly_1__model_10 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 11 2hdc__assembly_1__model_11 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 12 2hdc__assembly_1__model_12 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 13 2hdc__assembly_1__model_13 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 14 2hdc__assembly_1__model_14 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 15 2hdc__assembly_1__model_15 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 16 2hdc__assembly_1__model_16 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 17 2hdc__assembly_1__model_17 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 18 2hdc__assembly_1__model_18 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 19 2hdc__assembly_1__model_19 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
1 20 2hdc__assembly_1__model_20 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 2 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd2hdca_
Class classa — All alpha proteins
Fold Fold folda.4 — DNA/RNA-binding 3-helical bundle
Superfamily Superfamily superfamilya.4.5 — 'Winged helix' DNA-binding domain
Family Family familya.4.5.14 — Forkhead DNA-binding domain

CATH v4.4 (1 domains)

Domain ID domain_id2hdcA00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
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7. Citations (1)