2i00

Crystal structure of acetyltransferase (GNAT family) from Enterococcus faecalis

Method: X-RAY DIFFRACTION

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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Acetyltransferase, GNAT family

Enterococcus faecalis

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	蛋白同源多聚体	同源多聚体	蛋白 2	water × 2	与蛋白数一致
2	蛋白同源多聚体	同源多聚体	蛋白 2	water × 2	与蛋白数一致
3	蛋白同源多聚体	同源多聚体	蛋白 2	water × 2	与蛋白数一致
4	蛋白同源多聚体	同源多聚体	蛋白 6	water × 6	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	Q831Y9_ENTFA
Isoform	—
PDB实体	1
链与序列区间	作者链 A； PDB构建体 1–406； UniProt 1–406 作者链 B； PDB构建体 1–406； UniProt 1–406 作者链 C； PDB构建体 1–406； UniProt 1–406 作者链 D； PDB构建体 1–406； UniProt 1–406 作者链 E； PDB构建体 1–406； UniProt 1–406 作者链 F； PDB构建体 1–406； UniProt 1–406

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id	2i00
沉积日期 deposition_date	2006-08-09
结构标题 title	Crystal structure of acetyltransferase (GNAT family) from Enterococcus faecalis
关键词 keywords	;acetyltransferase, GNAT family, structural genomics, PSI-2, Protein Structure Initiative, Midwest Center for Structural Genomics, MCSG, TRANSFERASE ;; TRANSFERASE
实验方法 method	X-RAY DIFFRACTION

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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

2i00__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

2i00__assembly_1__model_1 | I(q)

100 个绘图点；横轴和纵轴均采用对数尺度。

2i00__assembly_1__model_1 | P(r) · Pending

P(r) 将按相同 assembly/model 分别计算和展示。

Rg（Guinier）	29.45 Å
Rg（电子密度）	28.34 Å
总 Rg	29.14 Å
原子数	6628
残基数	793
排除体积	117930 Å³
最大 q	0.500 Å⁻¹

Assembly	Model	结构单元	聚集说明	状态	CRYSOL	操作
1	1	`2i00__assembly_1__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
2	1	`2i00__assembly_2__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
3	1	`2i00__assembly_3__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
4	1	`2i00__assembly_4__model_1`	hexameric （6）	成功	4.1.3-1-20251215 (887e7ef)	查看下载

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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (2)

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6. 折叠分类 (SCOP + CATH) 30 domains

SCOP 2.08 (12 domains)

结构域编号 domain_id	d2i00a1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.106 — SCP-like
超家族 Superfamily superfamily	d.106.1 — SCP-like
家族 Family family	d.106.1.4 — EF1021 C-terminal domain-like

结构域编号 domain_id	d2i00a2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.108 — Acyl-CoA N-acyltransferases (Nat)
超家族 Superfamily superfamily	d.108.1 — Acyl-CoA N-acyltransferases (Nat)
家族 Family family	d.108.1.10 — EF1021-like

结构域编号 domain_id	d2i00b1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.106 — SCP-like
超家族 Superfamily superfamily	d.106.1 — SCP-like
家族 Family family	d.106.1.4 — EF1021 C-terminal domain-like

结构域编号 domain_id	d2i00b2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.108 — Acyl-CoA N-acyltransferases (Nat)
超家族 Superfamily superfamily	d.108.1 — Acyl-CoA N-acyltransferases (Nat)
家族 Family family	d.108.1.10 — EF1021-like

结构域编号 domain_id	d2i00c1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.106 — SCP-like
超家族 Superfamily superfamily	d.106.1 — SCP-like
家族 Family family	d.106.1.4 — EF1021 C-terminal domain-like

结构域编号 domain_id	d2i00c2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.108 — Acyl-CoA N-acyltransferases (Nat)
超家族 Superfamily superfamily	d.108.1 — Acyl-CoA N-acyltransferases (Nat)
家族 Family family	d.108.1.10 — EF1021-like

结构域编号 domain_id	d2i00d1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.106 — SCP-like
超家族 Superfamily superfamily	d.106.1 — SCP-like
家族 Family family	d.106.1.4 — EF1021 C-terminal domain-like

结构域编号 domain_id	d2i00d2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.108 — Acyl-CoA N-acyltransferases (Nat)
超家族 Superfamily superfamily	d.108.1 — Acyl-CoA N-acyltransferases (Nat)
家族 Family family	d.108.1.10 — EF1021-like

结构域编号 domain_id	d2i00e1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.106 — SCP-like
超家族 Superfamily superfamily	d.106.1 — SCP-like
家族 Family family	d.106.1.4 — EF1021 C-terminal domain-like

结构域编号 domain_id	d2i00e2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.108 — Acyl-CoA N-acyltransferases (Nat)
超家族 Superfamily superfamily	d.108.1 — Acyl-CoA N-acyltransferases (Nat)
家族 Family family	d.108.1.10 — EF1021-like

结构域编号 domain_id	d2i00f1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.106 — SCP-like
超家族 Superfamily superfamily	d.106.1 — SCP-like
家族 Family family	d.106.1.4 — EF1021 C-terminal domain-like

结构域编号 domain_id	d2i00f2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.108 — Acyl-CoA N-acyltransferases (Nat)
超家族 Superfamily superfamily	d.108.1 — Acyl-CoA N-acyltransferases (Nat)
家族 Family family	d.108.1.10 — EF1021-like

CATH v4.4 (18 domains)

结构域编号 domain_id	2i00A01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2i00A02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2i00A03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1050 — Nonspecific Lipid-transfer Protein; Chain A
同源超家族 H-superfamily homologous superfamily	10 — SCP2 sterol-binding domain

结构域编号 domain_id	2i00B01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2i00B02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2i00B03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1050 — Nonspecific Lipid-transfer Protein; Chain A
同源超家族 H-superfamily homologous superfamily	10 — SCP2 sterol-binding domain

结构域编号 domain_id	2i00C01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2i00C02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2i00C03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1050 — Nonspecific Lipid-transfer Protein; Chain A
同源超家族 H-superfamily homologous superfamily	10 — SCP2 sterol-binding domain

结构域编号 domain_id	2i00D01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2i00D02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2i00D03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1050 — Nonspecific Lipid-transfer Protein; Chain A
同源超家族 H-superfamily homologous superfamily	10 — SCP2 sterol-binding domain

结构域编号 domain_id	2i00E01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2i00E02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2i00E03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1050 — Nonspecific Lipid-transfer Protein; Chain A
同源超家族 H-superfamily homologous superfamily	10 — SCP2 sterol-binding domain

结构域编号 domain_id	2i00F01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2i00F02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2i00F03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1050 — Nonspecific Lipid-transfer Protein; Chain A
同源超家族 H-superfamily homologous superfamily	10 — SCP2 sterol-binding domain

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晶胞边长 a length_a	77.410 Å
晶胞边长 b length_b	177.091 Å
晶胞边长 c length_c	104.429 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	94.89 °
晶胞夹角 γ angle_gamma	90.00 °
晶胞分子数 Z z_pdb	12

空间群 space_group	P 1 21 1
空间群编号 int_tables_number	4
晶系 crystal_system	—

分辨率 resolution	2.300 Å
最低分辨率 resolution_low	41.920 Å
R 因子 r_factor	0.2158
R_work r_work	0.2130
R_free r_free	0.2698

描述 description	Acetyltransferase, GNAT family
分子量 formula_weight	48077.1 kDa
EC 编号 ec_number	2.3.1.1
来源方法 src_method	man
拷贝数 entity_count	6

聚合物类型 type	polypeptide(L)
链编号 strand_id	A,B,C,D,E,F
原子数 atom_count	20278

Crystal structure of acetyltransferase (GNAT family) from Enterococcus faecalis

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Acetyltransferase, GNAT family

当前结构中的状态

数据库中的同蛋白其他状态

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

2i00__assembly_1__model_1

2i00__assembly_1__model_1 | I(q)

2i00__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (2)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 water

6. 折叠分类 (SCOP + CATH) 30 domains

SCOP 2.08 (12 domains)

CATH v4.4 (18 domains)

7. 引用文献 (1)

来源生物 organism	Enterococcus faecalis
NCBI 分类编号 ncbi_taxonomy_id	226185
宿主生物 host_organism	Escherichia coli BL21

描述 description	water
分子量 formula_weight	18.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	376

Crystal structure of acetyltransferase (GNAT family) from Enterococcus faecalis

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Acetyltransferase, GNAT family

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

2i00__assembly_1__model_1

2i00__assembly_1__model_1 | I(q)

2i00__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (2)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 water

6. 折叠分类 (SCOP + CATH) 30 domains

SCOP 2.08 (12 domains)

CATH v4.4 (18 domains)

7. 引用文献 (1)