SAXSdb — 2j67

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1. Protein Identity and Related Structures Protein Identity & Related Structures

TOLL LIKE RECEPTOR 10

HOMO SAPIENS

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein homooligomer	Homooligomer	Protein 2	water × 2	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	TLR10_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 24–178； UniProt 622–776 Author chain B； PDBConstruct 24–178； UniProt 622–776

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	2j67
Deposition date deposition_date	2006-09-26
Structure title title	The TIR domain of human Toll-Like Receptor 10 (TLR10)
Keywords keywords	;TIR, IL-1, TOLL, TLR10, MEMBRANE, RECEPTOR, INFLAMMATORY RESPONSE, TOLL-LIKE RECEPTOR 10, INNATE IMMUNITY, IMMUNE RESPONSE, LEUCINE-RICH REPEAT, GLYCOPROTEIN, TRANSMEMBRANE ;; RECEPTOR
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2j67__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2j67__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

2j67__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	22.74 Å
Rg (electron density)	21.76 Å
Total Rg	22.86 Å
Atom count	2345
Residues	275
Excluded volume	42047 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`2j67__assembly_1__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

Domain ID domain_id	d2j67a_
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.23 — Flavodoxin-like
Superfamily Superfamily superfamily	c.23.2 — Toll/Interleukin receptor TIR domain
Family Family family	c.23.2.1 — Toll/Interleukin receptor TIR domain

Domain ID domain_id	d2j67b_
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.23 — Flavodoxin-like
Superfamily Superfamily superfamily	c.23.2 — Toll/Interleukin receptor TIR domain
Family Family family	c.23.2.1 — Toll/Interleukin receptor TIR domain

CATH v4.4 (2 domains)

Domain ID domain_id	2j67A00
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	10140 — Toll/interleukin-1 receptor homology (TIR) domain

Domain ID domain_id	2j67B00
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	10140 — Toll/interleukin-1 receptor homology (TIR) domain

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Unit-cell length a length_a	66.200 Å
Unit-cell length b length_b	43.300 Å
Unit-cell length c length_c	71.300 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	101.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	4

Space group space_group	P 1 21 1
Space-group number int_tables_number	4
Crystal system crystal_system	—

Resolution resolution	2.200 Å
Low-resolution limit resolution_low	23.430 Å
R factor r_factor	0.2160
R_work r_work	0.2140
R_free r_free	0.2660

Description description	TOLL LIKE RECEPTOR 10
Molecular weight formula_weight	21289.3 kDa
Source method src_method	man
Copy count entity_count	2

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B
Atom count atom_count	2476

The TIR domain of human Toll-Like Receptor 10 (TLR10)

1. Protein Identity and Related Structures Protein Identity & Related Structures

TOLL LIKE RECEPTOR 10

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2j67__assembly_1__model_1

2j67__assembly_1__model_1 | I(q)

2j67__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 water

6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

CATH v4.4 (2 domains)

7. Citations (1)

Source organism organism	HOMO SAPIENS
Common name common_name	HUMAN
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	ESCHERICHIA COLI

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	117

The TIR domain of human Toll-Like Receptor 10 (TLR10)

1. Protein Identity and Related Structures Protein Identity & Related Structures

TOLL LIKE RECEPTOR 10

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2j67__assembly_1__model_1

2j67__assembly_1__model_1 | I(q)

2j67__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 water

6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

CATH v4.4 (2 domains)

7. Citations (1)