2jfb

3D Structure of Lumazine Synthase from Candida albicans

Method: X-RAY DIFFRACTION

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1. 蛋白身份与相关结构 Protein Identity & Related Structures

当前条目没有可用的 UniProt 蛋白身份。

七张关系表仍保留该条目的 assembly 与组成信息，但缺少统一蛋白身份时，不能可靠建立跨 PDB 的同蛋白链接。

当前条目的 assembly 组成

Assembly	物理组成	蛋白状态	蛋白 / DNA / RNA / 其他聚合物	数据核对
1	蛋白同源多聚体	同源多聚体	5 / 0 / 0 / 0	与蛋白数一致
2	蛋白同源多聚体	同源多聚体	5 / 0 / 0 / 0	与蛋白数一致
3	蛋白同源多聚体	同源多聚体	5 / 0 / 0 / 0	与蛋白数一致

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id	2jfb
沉积日期 deposition_date	2007-01-30
结构标题 title	3D Structure of Lumazine Synthase from Candida albicans
关键词 keywords	TRANSFERASE, CANDIDA ALBICANS, LUMAZINE SYNTHASE, RIBOFLAVIN BIOSYNTHESIS; TRANSFERASE
实验方法 method	X-RAY DIFFRACTION

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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

2jfb__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

2jfb__assembly_1__model_1 | I(q)

100 个绘图点；横轴和纵轴均采用对数尺度。

2jfb__assembly_1__model_1 | P(r) · Pending

P(r) 将按相同 assembly/model 分别计算和展示。

Rg（Guinier）	27.90 Å
Rg（电子密度）	26.62 Å
总 Rg	27.57 Å
原子数	6013
残基数	765
排除体积	108350 Å³
最大 q	0.500 Å⁻¹

Assembly	Model	结构单元	聚集说明	状态	CRYSOL	操作
1	1	`2jfb__assembly_1__model_1`	pentameric （5）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
2	1	`2jfb__assembly_2__model_1`	pentameric （5）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
3	1	`2jfb__assembly_3__model_1`	pentameric （5）	成功	4.1.3-1-20251215 (887e7ef)	查看下载

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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (4)

实体 1 Entity 1 polymer

描述 description	6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE
分子量 formula_weight	18160.1 kDa
EC 编号 ec_number	2.5.1.9
来源方法 src_method	man
拷贝数 entity_count	15

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	A,B,C,D,E,F,G,H,I,J,K,L,M,N,O
原子数 atom_count	18754

MAVKGLGEVDQKYDGSKLRIGILHARWNRKIIDALVAGAVKRLQEFGVKEENIIIETVPGSFELPYGSKLFVEKQKRLGKPLDAIIPIGVLIKGSTMHFEYICDSTTHQLMKLNFELGIPVIFGVLTCLTDEQAEARAGLIEGKMHNHGEDWGAAAVEMATKFN

来源 Source

来源生物 organism	CANDIDA ALBICANS
NCBI 分类编号 ncbi_taxonomy_id	5476
宿主生物 host_organism	ESCHERICHIA COLI

实体 2 Entity 2 non-polymer

描述 description	PHOSPHATE ION
分子量 formula_weight	95.0 kDa
来源方法 src_method	syn
拷贝数 entity_count	15

实体 3 Entity 3 non-polymer

描述 description	(4S)-2-METHYL-2,4-PENTANEDIOL
分子量 formula_weight	118.2 kDa
来源方法 src_method	syn
拷贝数 entity_count	3

实体 4 Entity 4 water

描述 description	water
分子量 formula_weight	18.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	751

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6. 折叠分类 (SCOP + CATH) 30 domains

SCOP 2.08 (15 domains)

结构域编号 domain_id	d2jfba_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.16 — Lumazine synthase
超家族 Superfamily superfamily	c.16.1 — Lumazine synthase
家族 Family family	c.16.1.1 — Lumazine synthase

结构域编号 domain_id	d2jfbb_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.16 — Lumazine synthase
超家族 Superfamily superfamily	c.16.1 — Lumazine synthase
家族 Family family	c.16.1.1 — Lumazine synthase

结构域编号 domain_id	d2jfbc_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.16 — Lumazine synthase
超家族 Superfamily superfamily	c.16.1 — Lumazine synthase
家族 Family family	c.16.1.1 — Lumazine synthase

结构域编号 domain_id	d2jfbd_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.16 — Lumazine synthase
超家族 Superfamily superfamily	c.16.1 — Lumazine synthase
家族 Family family	c.16.1.1 — Lumazine synthase

结构域编号 domain_id	d2jfbe_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.16 — Lumazine synthase
超家族 Superfamily superfamily	c.16.1 — Lumazine synthase
家族 Family family	c.16.1.1 — Lumazine synthase

结构域编号 domain_id	d2jfbf_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.16 — Lumazine synthase
超家族 Superfamily superfamily	c.16.1 — Lumazine synthase
家族 Family family	c.16.1.1 — Lumazine synthase

结构域编号 domain_id	d2jfbg_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.16 — Lumazine synthase
超家族 Superfamily superfamily	c.16.1 — Lumazine synthase
家族 Family family	c.16.1.1 — Lumazine synthase

结构域编号 domain_id	d2jfbh_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.16 — Lumazine synthase
超家族 Superfamily superfamily	c.16.1 — Lumazine synthase
家族 Family family	c.16.1.1 — Lumazine synthase

结构域编号 domain_id	d2jfbi_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.16 — Lumazine synthase
超家族 Superfamily superfamily	c.16.1 — Lumazine synthase
家族 Family family	c.16.1.1 — Lumazine synthase

结构域编号 domain_id	d2jfbj_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.16 — Lumazine synthase
超家族 Superfamily superfamily	c.16.1 — Lumazine synthase
家族 Family family	c.16.1.1 — Lumazine synthase

结构域编号 domain_id	d2jfbk_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.16 — Lumazine synthase
超家族 Superfamily superfamily	c.16.1 — Lumazine synthase
家族 Family family	c.16.1.1 — Lumazine synthase

结构域编号 domain_id	d2jfbl_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.16 — Lumazine synthase
超家族 Superfamily superfamily	c.16.1 — Lumazine synthase
家族 Family family	c.16.1.1 — Lumazine synthase

结构域编号 domain_id	d2jfbm_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.16 — Lumazine synthase
超家族 Superfamily superfamily	c.16.1 — Lumazine synthase
家族 Family family	c.16.1.1 — Lumazine synthase

结构域编号 domain_id	d2jfbn_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.16 — Lumazine synthase
超家族 Superfamily superfamily	c.16.1 — Lumazine synthase
家族 Family family	c.16.1.1 — Lumazine synthase

结构域编号 domain_id	d2jfbo_
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.16 — Lumazine synthase
超家族 Superfamily superfamily	c.16.1 — Lumazine synthase
家族 Family family	c.16.1.1 — Lumazine synthase

CATH v4.4 (15 domains)

结构域编号 domain_id	2jfbA00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	960 — Lumazine/riboflavin synthase

结构域编号 domain_id	2jfbB00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	960 — Lumazine/riboflavin synthase

结构域编号 domain_id	2jfbC00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	960 — Lumazine/riboflavin synthase

结构域编号 domain_id	2jfbD00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	960 — Lumazine/riboflavin synthase

结构域编号 domain_id	2jfbE00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	960 — Lumazine/riboflavin synthase

结构域编号 domain_id	2jfbF00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	960 — Lumazine/riboflavin synthase

结构域编号 domain_id	2jfbG00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	960 — Lumazine/riboflavin synthase

结构域编号 domain_id	2jfbH00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	960 — Lumazine/riboflavin synthase

结构域编号 domain_id	2jfbI00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	960 — Lumazine/riboflavin synthase

结构域编号 domain_id	2jfbJ00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	960 — Lumazine/riboflavin synthase

结构域编号 domain_id	2jfbK00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	960 — Lumazine/riboflavin synthase

结构域编号 domain_id	2jfbL00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	960 — Lumazine/riboflavin synthase

结构域编号 domain_id	2jfbM00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	960 — Lumazine/riboflavin synthase

结构域编号 domain_id	2jfbN00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	960 — Lumazine/riboflavin synthase

结构域编号 domain_id	2jfbO00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	960 — Lumazine/riboflavin synthase

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晶胞边长 a length_a	128.648 Å
晶胞边长 b length_b	128.648 Å
晶胞边长 c length_c	284.965 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	90.00 °
晶胞夹角 γ angle_gamma	120.00 °
晶胞分子数 Z z_pdb	90

空间群 space_group	P 31 2 1
空间群编号 int_tables_number	152
晶系 crystal_system	—

分辨率 resolution	2.500 Å
最低分辨率 resolution_low	15.000 Å
R 因子 r_factor	0.2130
R_work r_work	0.2100
R_free r_free	0.2600