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2kb8

The dynamic alpha-helix structure of micelle-bound human amylin.

Method: SOLUTION NMR
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Islet amyloid polypeptide

Homo sapiens

UniProt P10997

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 No other associated polymer Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1kuw 2kb8 2l86 3fr1 5mgq 6ucj 6uck

7 assemblies

Homodimer
3fr1 3fr1

2 assemblies

Homotetramer

None

Other homooligomers
5knz 5ko0 6y1a 6zrf 6zrq 6zrr 7m61 7m62 7m64 7m65 7ykw 7yl0

39 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
2g48 2g48 3g7v 3g7v 3g7w 3g7w 3hgz 3hgz 5k5g 6vw2 7bg0 7bg0

14 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name IAPP_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–37； UniProt 34–70

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2kb8
Deposition date deposition_date2008-11-21
Structure title titleThe dynamic alpha-helix structure of micelle-bound human amylin.
Keywords keywordsIAPP, amyloid, Micelle-bound, type II diabetes, hormone, Amidation, Cleavage on pair of basic residues, Polymorphism, Secreted; HORMONE
Experimental Method methodSOLUTION NMR
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2kb8__assembly_1__model_10

Assembly 1 · Model 10 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2kb8__assembly_1__model_10 | I(q)

10-2 10-1 105 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2kb8__assembly_1__model_10 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）15.86 Å
Rg (electron density)15.46 Å
Total Rg16.27 Å
Atom count535
Residues37
Excluded volume4753 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2kb8__assembly_1__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 2 2kb8__assembly_1__model_2 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 3 2kb8__assembly_1__model_3 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 4 2kb8__assembly_1__model_4 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 5 2kb8__assembly_1__model_5 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 6 2kb8__assembly_1__model_6 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 7 2kb8__assembly_1__model_7 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 8 2kb8__assembly_1__model_8 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 9 2kb8__assembly_1__model_9 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 10 2kb8__assembly_1__model_10 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 11 2kb8__assembly_1__model_11 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 12 2kb8__assembly_1__model_12 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 13 2kb8__assembly_1__model_13 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 14 2kb8__assembly_1__model_14 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 15 2kb8__assembly_1__model_15 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 16 2kb8__assembly_1__model_16 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 17 2kb8__assembly_1__model_17 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 18 2kb8__assembly_1__model_18 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 19 2kb8__assembly_1__model_19 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 20 2kb8__assembly_1__model_20 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 21 2kb8__assembly_1__model_21 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 22 2kb8__assembly_1__model_22 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 23 2kb8__assembly_1__model_23 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 24 2kb8__assembly_1__model_24 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 25 2kb8__assembly_1__model_25 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 26 2kb8__assembly_1__model_26 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 27 2kb8__assembly_1__model_27 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 28 2kb8__assembly_1__model_28 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 29 2kb8__assembly_1__model_29 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
1 30 2kb8__assembly_1__model_30 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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7. Citations (1)