Heat shock protein 70
Escherichia coli
当前结构中的状态
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白单体 | 单体 | 蛋白 1 | 无其他共同聚合物 | 与蛋白数一致 |
数据库中的同蛋白其他状态
查看构建体与数据证据
| UniProt名称 | DNAK_ECOLI |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 1–605； UniProt 1–605 |
2kho
NMR-RDC / XRAY structure of E. coli HSP70 (DNAK) chaperone (1-605) complexed with ADP and substrate
1. 蛋白身份与相关结构 Protein Identity & Related Structures
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
2. 结构基本信息 2. Structure Basics
| 条目编号 entry_id | 2kho |
| 沉积日期 deposition_date | 2009-04-10 |
| 结构标题 title | NMR-RDC / XRAY structure of E. coli HSP70 (DNAK) chaperone (1-605) complexed with ADP and substrate |
| 关键词 keywords | ;MOLECULAR CHAPERONE, HSP70, PEPTIDE BINDING, PROTEIN FOLDING, ATP-binding, Cell inner membrane, Cell membrane, Chaperone, DNA replication, Membrane, Nucleotide-binding, Phosphoprotein, Stress response, TRANSCRIPTION ;; CHAPERONE |
| 实验方法 method | SOLUTION NMR |
3. Official assembly/model 理论 SAXS Official SAXS Profiles
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
2kho__assembly_1__model_1
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
2kho__assembly_1__model_1 | I(q)
2kho__assembly_1__model_1 | P(r) · Pending
| Rg（Guinier） | 37.11 Å |
| Rg（电子密度） | 37.63 Å |
| 总 Rg | 37.69 Å |
| 原子数 | 5078 |
| 残基数 | 600 |
| 排除体积 | 80246 ų |
| 最大 q | 0.500 Å⁻¹ |
4. 晶体学与实验 4. Crystallography & Experiment
5. 实体与聚合物信息 Entities & Polymers (1)
6. 折叠分类 (SCOP + CATH) 6 domains
CATH v4.4 (6 domains)
| 结构域编号 domain_id | 2khoA01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 420 — Nucleotidyltransferase; domain 5 |
| 同源超家族 H-superfamily homologous superfamily | 40 — ATPase, nucleotide binding domain |
| 结构域编号 domain_id | 2khoA02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 30 — Defensin A-like |
| 同源超家族 H-superfamily homologous superfamily | 30 — |
| 结构域编号 domain_id | 2khoA03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 420 — Nucleotidyltransferase; domain 5 |
| 同源超家族 H-superfamily homologous superfamily | 40 — ATPase, nucleotide binding domain |
| 结构域编号 domain_id | 2khoA04 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 640 — Actin; Chain A, domain 4 |
| 同源超家族 H-superfamily homologous superfamily | 10 — ATPase, substrate binding domain, subdomain 4 |
| 结构域编号 domain_id | 2khoA05 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 60 — Sandwich |
| 拓扑 Topology topology | 34 — Substrate Binding Domain Of DNAk; Chain A, domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Substrate Binding Domain Of DNAk; Chain A, domain 1 |
| 结构域编号 domain_id | 2khoA06 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 1270 — Substrate Binding Domain Of Dnak; Chain:A; Domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 10 — |