2kt5

RRM domain of mRNA export adaptor REF2-I bound to HSV-1 ICP27 peptide

Method: SOLUTION NMR
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1. Protein Identity and Related Structures Protein Identity & Related Structures

RNA and export factor-binding protein 2

Mus musculus

UniProt Q9JJW6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 ICP27 × 1 (Q9J0X9) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name REFP2_MOUSE
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 14–116; UniProt 53–155

ICP27

Human herpesvirus 1

UniProt Q9J0X9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 RNA and export factor-binding protein 2 × 1 (Q9JJW6) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name Q9J0X9_HHV1
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B; PDBConstruct 5–40; UniProt 103–138

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2kt5
Deposition date deposition_date2010-01-18
Structure title titleRRM domain of mRNA export adaptor REF2-I bound to HSV-1 ICP27 peptide
Keywords keywords;REF ICP27 HSV-1, Chaperone, mRNA processing, mRNA splicing, mRNA transport, Nucleus, RNA-binding, Spliceosome, Transport, RNA Binding Protein - Viral Protein complex ;; RNA Binding Protein / Viral Protein
Experimental Method methodSOLUTION NMR
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2kt5__assembly_1__model_5

Assembly 1 · Model 5 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2kt5__assembly_1__model_5 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2kt5__assembly_1__model_5 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)24.56 Å
Rg (electron density)24.62 Å
Total Rg25.32 Å
Atom count2464
Residues164
Excluded volume21811 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2kt5__assembly_1__model_1 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 2 2kt5__assembly_1__model_2 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 3 2kt5__assembly_1__model_3 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 4 2kt5__assembly_1__model_4 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 5 2kt5__assembly_1__model_5 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 6 2kt5__assembly_1__model_6 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 7 2kt5__assembly_1__model_7 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 8 2kt5__assembly_1__model_8 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 9 2kt5__assembly_1__model_9 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 10 2kt5__assembly_1__model_10 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 11 2kt5__assembly_1__model_11 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 12 2kt5__assembly_1__model_12 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 13 2kt5__assembly_1__model_13 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 14 2kt5__assembly_1__model_14 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 15 2kt5__assembly_1__model_15 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 16 2kt5__assembly_1__model_16 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 17 2kt5__assembly_1__model_17 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 18 2kt5__assembly_1__model_18 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 19 2kt5__assembly_1__model_19 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 20 2kt5__assembly_1__model_20 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 1 domains

CATH v4.4 (1 domains)

Domain ID domain_id2kt5A00
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily330 — RRM (RNA recognition motif) domain
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7. Citations (1)