Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | Protein 2 | Protein AF-9 × 1 （P42568） | Consistent with protein count |
| UniProt name | CBX8_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 2–24； UniProt 327–349 |
Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | Protein 2 | Chromobox protein homolog 8 × 1 （Q9HC52） | Consistent with protein count |
| UniProt name | AF9_HUMAN |
| Isoform | — |
| PDB entities | 2 |
| Chains and sequence ranges | Author chain B； PDBConstruct 2–70； UniProt 500–568 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 2n4q |
| Deposition date deposition_date | 2015-06-30 |
| Structure title title | Solution NMR structure of CBX8 in complex with AF9 (CBX8-AF9) |
| Keywords keywords | ;AF9, MLLT3, CBX8, hPC3, H3K27me3, DOT1L, AF4, Mixed Lineage Leukemia, MLL-AF9, MLL, Intrinsically Disordered Protein, IDP, PRC1, Polycomb, Polycomb Group Proteins, chromobox homolog 8, Leukemia, TRANSCRIPTION ;; TRANSCRIPTION |
| Experimental Method method | SOLUTION NMR |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 2 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 16.60 Å |
| Rg (electron density) | 14.92 Å |
| Total Rg | 16.22 Å |
| Atom count | 1532 |
| Residues | 94 |
| Excluded volume | 13509 ų |
| Maximum q | 0.500 Å⁻¹ |
| Assembly | Model | Structure unit | Oligomeric description | Status | CRYSOL | Actions |
|---|---|---|---|---|---|---|
| 1 | 1 | 2n4q__assembly_1__model_1 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 2 | 2n4q__assembly_1__model_2 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 3 | 2n4q__assembly_1__model_3 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 4 | 2n4q__assembly_1__model_4 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 5 | 2n4q__assembly_1__model_5 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 6 | 2n4q__assembly_1__model_6 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 7 | 2n4q__assembly_1__model_7 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 8 | 2n4q__assembly_1__model_8 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 9 | 2n4q__assembly_1__model_9 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 10 | 2n4q__assembly_1__model_10 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |