2o90

Atomic resolution crystal structure of E.coli dihydroneopterin aldolase in complex with neopterin

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Dihydroneopterin aldolase

Escherichia coli

UniProt P0AC16

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 8 L-NEOPTERIN × 8 water × 8 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name FOLB_ECOLI
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–122; UniProt 1–122

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2o90
Deposition date deposition_date2006-12-12
Structure title titleAtomic resolution crystal structure of E.coli dihydroneopterin aldolase in complex with neopterin
Keywords keywordsDIHYDRONEOPTERIN ALDOLASE, DHNA, NEOPTERIN, MONAPTERIN, 7, 8-DIHYDRONEOPTERIN, DRUG DESIGN, ATOMIC RESOLUTION, LYASE; LYASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2o90__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2o90__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2o90__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)29.45 Å
Rg (electron density)27.91 Å
Total Rg28.78 Å
Atom count7344
Residues920
Excluded volume131000 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2o90__assembly_1__model_1 octameric (8) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 2 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd2o90a_
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.96 — T-fold
Superfamily Superfamily superfamilyd.96.1 — Tetrahydrobiopterin biosynthesis enzymes-like
Family Family familyd.96.1.0 — automated matches

CATH v4.4 (1 domains)

Domain ID domain_id2o90A00
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1130 — GTP Cyclohydrolase I, domain 2
Homologous superfamily homologous superfamily10 — GTP cyclohydrolase I, C-terminal domain/NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal domain
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7. Citations (1)