2oar

Mechanosensitive Channel of Large Conductance (MscL)

Method: X-RAY DIFFRACTION
▼

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Large-conductance mechanosensitive channel

Mycobacterium tuberculosis H37Ra

UniProt P0A5K8

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白同源多聚体 同源多聚体 蛋白 5 GOLD ION × 3 与蛋白数一致
2 蛋白同源多聚体 同源多聚体 蛋白 10 GOLD ION × 6 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 MSCL_MYCTU
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 24–174; UniProt 1–151 作者链 B; PDB构建体 24–174; UniProt 1–151 作者链 C; PDB构建体 24–174; UniProt 1–151 作者链 D; PDB构建体 24–174; UniProt 1–151 作者链 E; PDB构建体 24–174; UniProt 1–151

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

▼

2. 结构基本信息 2. Structure Basics

条目编号 entry_id2oar
沉积日期 deposition_date2006-12-17
结构标题 titleMechanosensitive Channel of Large Conductance (MscL)
关键词 keywordsstretch activated ion channel mechanosensitive, MEMBRANE PROTEIN; MEMBRANE PROTEIN
实验方法 methodX-RAY DIFFRACTION
▼

3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

2oar__assembly_2__model_1

Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

2oar__assembly_2__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

2oar__assembly_2__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)44.94 Å
Rg(电子密度)45.54 Å
总 Rg45.15 Å
原子数9515
残基数1250
排除体积174370 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 2oar__assembly_1__model_1 pentameric (5) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
2 1 2oar__assembly_2__model_1 decameric (10) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
▶

4. 晶体学与实验 4. Crystallography & Experiment

▶

5. 实体与聚合物信息 Entities & Polymers (2)

▼

6. 折叠分类 (SCOP + CATH) 13 domains

SCOP 2.08 (5 domains)

结构域编号 domain_idd2oara1
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.16 — Gated mechanosensitive channel
超家族 Superfamily superfamilyf.16.1 — Gated mechanosensitive channel
家族 Family familyf.16.1.1 — Gated mechanosensitive channel
结构域编号 domain_idd2oarb1
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.16 — Gated mechanosensitive channel
超家族 Superfamily superfamilyf.16.1 — Gated mechanosensitive channel
家族 Family familyf.16.1.1 — Gated mechanosensitive channel
结构域编号 domain_idd2oarc1
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.16 — Gated mechanosensitive channel
超家族 Superfamily superfamilyf.16.1 — Gated mechanosensitive channel
家族 Family familyf.16.1.1 — Gated mechanosensitive channel
结构域编号 domain_idd2oard1
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.16 — Gated mechanosensitive channel
超家族 Superfamily superfamilyf.16.1 — Gated mechanosensitive channel
家族 Family familyf.16.1.1 — Gated mechanosensitive channel
结构域编号 domain_idd2oare1
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.16 — Gated mechanosensitive channel
超家族 Superfamily superfamilyf.16.1 — Gated mechanosensitive channel
家族 Family familyf.16.1.1 — Gated mechanosensitive channel

CATH v4.4 (8 domains)

结构域编号 domain_id2oarA01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology1200 — Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A
同源超家族 H-superfamily homologous superfamily120 — Large-conductance mechanosensitive channel, MscL; domain 1
结构域编号 domain_id2oarA02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
同源超家族 H-superfamily homologous superfamily220 —
结构域编号 domain_id2oarB00
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology1200 — Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A
同源超家族 H-superfamily homologous superfamily120 — Large-conductance mechanosensitive channel, MscL; domain 1
结构域编号 domain_id2oarC01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology1200 — Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A
同源超家族 H-superfamily homologous superfamily120 — Large-conductance mechanosensitive channel, MscL; domain 1
结构域编号 domain_id2oarC02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
同源超家族 H-superfamily homologous superfamily220 —
结构域编号 domain_id2oarD00
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology1200 — Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A
同源超家族 H-superfamily homologous superfamily120 — Large-conductance mechanosensitive channel, MscL; domain 1
结构域编号 domain_id2oarE01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology1200 — Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A
同源超家族 H-superfamily homologous superfamily120 — Large-conductance mechanosensitive channel, MscL; domain 1
结构域编号 domain_id2oarE02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
同源超家族 H-superfamily homologous superfamily220 —
▶

7. 引用文献 (3)