2oau

Mechanosensitive Channel of Small Conductance (MscS)

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Small-conductance mechanosensitive channel

Escherichia coli

UniProt P0C0S1

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白同源多聚体 同源多聚体 蛋白 7 无其他共同聚合物 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 MSCS_ECOLI
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 21–306; UniProt 1–286 作者链 B; PDB构建体 21–306; UniProt 1–286 作者链 C; PDB构建体 21–306; UniProt 1–286 作者链 D; PDB构建体 21–306; UniProt 1–286 作者链 E; PDB构建体 21–306; UniProt 1–286 作者链 F; PDB构建体 21–306; UniProt 1–286 作者链 G; PDB构建体 21–306; UniProt 1–286

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id2oau
沉积日期 deposition_date2006-12-17
结构标题 titleMechanosensitive Channel of Small Conductance (MscS)
关键词 keywordsstretch activated, mechanosensitive ion channel, membrane protein; MEMBRANE PROTEIN
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

2oau__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

2oau__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

2oau__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)40.64 Å
Rg(电子密度)40.19 Å
总 Rg40.69 Å
原子数13573
残基数1778
排除体积245960 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 2oau__assembly_1__model_1 heptameric (7) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (1)

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6. 折叠分类 (SCOP + CATH) 42 domains

SCOP 2.08 (21 domains)

结构域编号 domain_idd2oaua1
类 Class classb — All beta proteins
折叠类型 Fold foldb.38 — Sm-like fold
超家族 Superfamily superfamilyb.38.1 — Sm-like ribonucleoproteins
家族 Family familyb.38.1.3 — Mechanosensitive channel protein MscS (YggB), middle domain
结构域编号 domain_idd2oaua2
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.58 — Ferredoxin-like
超家族 Superfamily superfamilyd.58.43 — Mechanosensitive channel protein MscS (YggB), C-terminal domain
家族 Family familyd.58.43.1 — Mechanosensitive channel protein MscS (YggB), C-terminal domain
结构域编号 domain_idd2oaua3
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.34 — Mechanosensitive channel protein MscS (YggB), transmembrane region
超家族 Superfamily superfamilyf.34.1 — Mechanosensitive channel protein MscS (YggB), transmembrane region
家族 Family familyf.34.1.1 — Mechanosensitive channel protein MscS (YggB), transmembrane region
结构域编号 domain_idd2oaub1
类 Class classb — All beta proteins
折叠类型 Fold foldb.38 — Sm-like fold
超家族 Superfamily superfamilyb.38.1 — Sm-like ribonucleoproteins
家族 Family familyb.38.1.3 — Mechanosensitive channel protein MscS (YggB), middle domain
结构域编号 domain_idd2oaub2
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.58 — Ferredoxin-like
超家族 Superfamily superfamilyd.58.43 — Mechanosensitive channel protein MscS (YggB), C-terminal domain
家族 Family familyd.58.43.1 — Mechanosensitive channel protein MscS (YggB), C-terminal domain
结构域编号 domain_idd2oaub3
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.34 — Mechanosensitive channel protein MscS (YggB), transmembrane region
超家族 Superfamily superfamilyf.34.1 — Mechanosensitive channel protein MscS (YggB), transmembrane region
家族 Family familyf.34.1.1 — Mechanosensitive channel protein MscS (YggB), transmembrane region
结构域编号 domain_idd2oauc1
类 Class classb — All beta proteins
折叠类型 Fold foldb.38 — Sm-like fold
超家族 Superfamily superfamilyb.38.1 — Sm-like ribonucleoproteins
家族 Family familyb.38.1.3 — Mechanosensitive channel protein MscS (YggB), middle domain
结构域编号 domain_idd2oauc2
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.58 — Ferredoxin-like
超家族 Superfamily superfamilyd.58.43 — Mechanosensitive channel protein MscS (YggB), C-terminal domain
家族 Family familyd.58.43.1 — Mechanosensitive channel protein MscS (YggB), C-terminal domain
结构域编号 domain_idd2oauc3
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.34 — Mechanosensitive channel protein MscS (YggB), transmembrane region
超家族 Superfamily superfamilyf.34.1 — Mechanosensitive channel protein MscS (YggB), transmembrane region
家族 Family familyf.34.1.1 — Mechanosensitive channel protein MscS (YggB), transmembrane region
结构域编号 domain_idd2oaud1
类 Class classb — All beta proteins
折叠类型 Fold foldb.38 — Sm-like fold
超家族 Superfamily superfamilyb.38.1 — Sm-like ribonucleoproteins
家族 Family familyb.38.1.3 — Mechanosensitive channel protein MscS (YggB), middle domain
结构域编号 domain_idd2oaud2
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.58 — Ferredoxin-like
超家族 Superfamily superfamilyd.58.43 — Mechanosensitive channel protein MscS (YggB), C-terminal domain
家族 Family familyd.58.43.1 — Mechanosensitive channel protein MscS (YggB), C-terminal domain
结构域编号 domain_idd2oaud3
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.34 — Mechanosensitive channel protein MscS (YggB), transmembrane region
超家族 Superfamily superfamilyf.34.1 — Mechanosensitive channel protein MscS (YggB), transmembrane region
家族 Family familyf.34.1.1 — Mechanosensitive channel protein MscS (YggB), transmembrane region
结构域编号 domain_idd2oaue1
类 Class classb — All beta proteins
折叠类型 Fold foldb.38 — Sm-like fold
超家族 Superfamily superfamilyb.38.1 — Sm-like ribonucleoproteins
家族 Family familyb.38.1.3 — Mechanosensitive channel protein MscS (YggB), middle domain
结构域编号 domain_idd2oaue2
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.58 — Ferredoxin-like
超家族 Superfamily superfamilyd.58.43 — Mechanosensitive channel protein MscS (YggB), C-terminal domain
家族 Family familyd.58.43.1 — Mechanosensitive channel protein MscS (YggB), C-terminal domain
结构域编号 domain_idd2oaue3
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.34 — Mechanosensitive channel protein MscS (YggB), transmembrane region
超家族 Superfamily superfamilyf.34.1 — Mechanosensitive channel protein MscS (YggB), transmembrane region
家族 Family familyf.34.1.1 — Mechanosensitive channel protein MscS (YggB), transmembrane region
结构域编号 domain_idd2oauf1
类 Class classb — All beta proteins
折叠类型 Fold foldb.38 — Sm-like fold
超家族 Superfamily superfamilyb.38.1 — Sm-like ribonucleoproteins
家族 Family familyb.38.1.3 — Mechanosensitive channel protein MscS (YggB), middle domain
结构域编号 domain_idd2oauf2
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.58 — Ferredoxin-like
超家族 Superfamily superfamilyd.58.43 — Mechanosensitive channel protein MscS (YggB), C-terminal domain
家族 Family familyd.58.43.1 — Mechanosensitive channel protein MscS (YggB), C-terminal domain
结构域编号 domain_idd2oauf3
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.34 — Mechanosensitive channel protein MscS (YggB), transmembrane region
超家族 Superfamily superfamilyf.34.1 — Mechanosensitive channel protein MscS (YggB), transmembrane region
家族 Family familyf.34.1.1 — Mechanosensitive channel protein MscS (YggB), transmembrane region
结构域编号 domain_idd2oaug1
类 Class classb — All beta proteins
折叠类型 Fold foldb.38 — Sm-like fold
超家族 Superfamily superfamilyb.38.1 — Sm-like ribonucleoproteins
家族 Family familyb.38.1.3 — Mechanosensitive channel protein MscS (YggB), middle domain
结构域编号 domain_idd2oaug2
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.58 — Ferredoxin-like
超家族 Superfamily superfamilyd.58.43 — Mechanosensitive channel protein MscS (YggB), C-terminal domain
家族 Family familyd.58.43.1 — Mechanosensitive channel protein MscS (YggB), C-terminal domain
结构域编号 domain_idd2oaug3
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.34 — Mechanosensitive channel protein MscS (YggB), transmembrane region
超家族 Superfamily superfamilyf.34.1 — Mechanosensitive channel protein MscS (YggB), transmembrane region
家族 Family familyf.34.1.1 — Mechanosensitive channel protein MscS (YggB), transmembrane region

CATH v4.4 (21 domains)

结构域编号 domain_id2oauA01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily1260 —
结构域编号 domain_id2oauA02
类 Class class2 — Mainly Beta
架构 Architecture architecture30 — Roll
拓扑 Topology topology30 — SH3 type barrels.
同源超家族 H-superfamily homologous superfamily60 —
结构域编号 domain_id2oauA03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily100 —
结构域编号 domain_id2oauB01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily1260 —
结构域编号 domain_id2oauB02
类 Class class2 — Mainly Beta
架构 Architecture architecture30 — Roll
拓扑 Topology topology30 — SH3 type barrels.
同源超家族 H-superfamily homologous superfamily60 —
结构域编号 domain_id2oauB03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily100 —
结构域编号 domain_id2oauC01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily1260 —
结构域编号 domain_id2oauC02
类 Class class2 — Mainly Beta
架构 Architecture architecture30 — Roll
拓扑 Topology topology30 — SH3 type barrels.
同源超家族 H-superfamily homologous superfamily60 —
结构域编号 domain_id2oauC03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily100 —
结构域编号 domain_id2oauD01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily1260 —
结构域编号 domain_id2oauD02
类 Class class2 — Mainly Beta
架构 Architecture architecture30 — Roll
拓扑 Topology topology30 — SH3 type barrels.
同源超家族 H-superfamily homologous superfamily60 —
结构域编号 domain_id2oauD03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily100 —
结构域编号 domain_id2oauE01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily1260 —
结构域编号 domain_id2oauE02
类 Class class2 — Mainly Beta
架构 Architecture architecture30 — Roll
拓扑 Topology topology30 — SH3 type barrels.
同源超家族 H-superfamily homologous superfamily60 —
结构域编号 domain_id2oauE03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily100 —
结构域编号 domain_id2oauF01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily1260 —
结构域编号 domain_id2oauF02
类 Class class2 — Mainly Beta
架构 Architecture architecture30 — Roll
拓扑 Topology topology30 — SH3 type barrels.
同源超家族 H-superfamily homologous superfamily60 —
结构域编号 domain_id2oauF03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily100 —
结构域编号 domain_id2oauG01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily1260 —
结构域编号 domain_id2oauG02
类 Class class2 — Mainly Beta
架构 Architecture architecture30 — Roll
拓扑 Topology topology30 — SH3 type barrels.
同源超家族 H-superfamily homologous superfamily60 —
结构域编号 domain_id2oauG03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily100 —
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7. 引用文献 (2)