Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein monomer | Monomer | Protein 1 | water × 1 | Consistent with protein count |
| UniProt name | GPX4_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 15–183； UniProt 29–197 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 2obi |
| Deposition date deposition_date | 2006-12-19 |
| Structure title title | Crystal structure of the Selenocysteine to Cysteine Mutant of human phospholipid hydroperoxide glutathione peroxidase (GPx4) |
| Keywords keywords | HUMAN GPX4, PEROXIDASE, SELENOPROTEIN, THIOREDOXIN-FOLD, ANTI-OXIDATVE DEFENSE SYSTEM, Oxidoreductase; OXIDOREDUCTASE |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 16.14 Å |
| Rg (electron density) | 14.64 Å |
| Total Rg | 15.88 Å |
| Atom count | 1330 |
| Residues | 165 |
| Excluded volume | 23699 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d2obia_ |
| Class class | c — Alpha and beta proteins (a/b) |
| Fold Fold fold | c.47 — Thioredoxin fold |
| Superfamily Superfamily superfamily | c.47.1 — Thioredoxin-like |
| Family Family family | c.47.1.0 — automated matches |
| Domain ID domain_id | 2obiA00 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| Topology topology | 30 — Glutaredoxin |
| Homologous superfamily homologous superfamily | 10 — Glutaredoxin |