Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白同源多聚体 | 同源多聚体 | 蛋白 4 | ZINC ION × 4 P1-(5'-ADENOSYL)P4-(5'-(2'-DEOXY-THYMIDYL))TETRAPHOSPHATE × 4 water × 4 | 与蛋白数一致 |
| 2 | 蛋白同源多聚体 | 同源多聚体 | 蛋白 2 | ZINC ION × 2 P1-(5'-ADENOSYL)P4-(5'-(2'-DEOXY-THYMIDYL))TETRAPHOSPHATE × 2 water × 2 | 与蛋白数一致 |
| UniProt名称 | KITH_HUMAN |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 1–234； UniProt 1–234 作者链 B； PDB构建体 1–234； UniProt 1–234 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 2orv |
| 沉积日期 deposition_date | 2007-02-04 |
| 结构标题 title | human Thymidine Kinase 1 in complex with TP4A |
| 关键词 keywords | ;TK-1 (THYMIDINE KINASE 1), TP4A (P1-(5'-ADENOSYL)P4-(5'-(2'DEOXYTHYMIDIL))TETRAPHOSPHATE, TRANSFERASE ;; TRANSFERASE |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 25.16 Å |
| Rg（电子密度） | 24.36 Å |
| 总 Rg | 25.19 Å |
| 原子数 | 5094 |
| 残基数 | 646 |
| 排除体积 | 91566 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d2orva1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.37 — P-loop containing nucleoside triphosphate hydrolases |
| 超家族 Superfamily superfamily | c.37.1 — P-loop containing nucleoside triphosphate hydrolases |
| 家族 Family family | c.37.1.24 — Type II thymidine kinase |
| 结构域编号 domain_id | d2orva2 |
| 类 Class class | g — Small proteins |
| 折叠类型 Fold fold | g.39 — Glucocorticoid receptor-like (DNA-binding domain) |
| 超家族 Superfamily superfamily | g.39.1 — Glucocorticoid receptor-like (DNA-binding domain) |
| 家族 Family family | g.39.1.14 — Type II thymidine kinase zinc finger |
| 结构域编号 domain_id | d2orvb1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.37 — P-loop containing nucleoside triphosphate hydrolases |
| 超家族 Superfamily superfamily | c.37.1 — P-loop containing nucleoside triphosphate hydrolases |
| 家族 Family family | c.37.1.24 — Type II thymidine kinase |
| 结构域编号 domain_id | d2orvb2 |
| 类 Class class | g — Small proteins |
| 折叠类型 Fold fold | g.39 — Glucocorticoid receptor-like (DNA-binding domain) |
| 超家族 Superfamily superfamily | g.39.1 — Glucocorticoid receptor-like (DNA-binding domain) |
| 家族 Family family | g.39.1.14 — Type II thymidine kinase zinc finger |
| 结构域编号 domain_id | 2orvA01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 300 — P-loop containing nucleotide triphosphate hydrolases |
| 结构域编号 domain_id | 2orvA02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 60 — Wheat Germ Agglutinin (Isolectin 2); domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 20 — |
| 结构域编号 domain_id | 2orvB01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 300 — P-loop containing nucleotide triphosphate hydrolases |
| 结构域编号 domain_id | 2orvB02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 60 — Wheat Germ Agglutinin (Isolectin 2); domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 20 — |