2p7p

Crystal structure of genomically encoded fosfomycin resistance protein, FosX, from Listeria monocytogenes complexed with MN(II) and sulfate ion

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Glyoxalase family protein

Listeria monocytogenes

UniProt Q71YW5

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白同源多聚体 同源多聚体 蛋白 2 MANGANESE (II) ION × 2 SULFATE ION × 2 water × 2 与蛋白数一致
2 蛋白同源多聚体 同源多聚体 蛋白 2 MANGANESE (II) ION × 2 SULFATE ION × 2 water × 2 与蛋白数一致
3 蛋白同源多聚体 同源多聚体 蛋白 2 MANGANESE (II) ION × 2 SULFATE ION × 2 water × 2 与蛋白数一致
4 蛋白同源多聚体 同源多聚体 蛋白 6 MANGANESE (II) ION × 6 SULFATE ION × 6 water × 6 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 Q71YW5_LISMF
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 1–133; UniProt 1–133 作者链 B; PDB构建体 1–133; UniProt 1–133 作者链 C; PDB构建体 1–133; UniProt 1–133 作者链 D; PDB构建体 1–133; UniProt 1–133 作者链 E; PDB构建体 1–133; UniProt 1–133 作者链 F; PDB构建体 1–133; UniProt 1–133

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id2p7p
沉积日期 deposition_date2007-03-20
结构标题 titleCrystal structure of genomically encoded fosfomycin resistance protein, FosX, from Listeria monocytogenes complexed with MN(II) and sulfate ion
关键词 keywordsFOSFOMYCIN RESISTANCE PROTEIN, MN BINDING, ANTIBIOTIC RESISTANCE, METAL BINDING PROTEIN, hydrolase; METAL BINDING PROTEIN, hydrolase
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

2p7p__assembly_2__model_1

Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

2p7p__assembly_2__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

2p7p__assembly_2__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)19.58 Å
Rg(电子密度)18.25 Å
总 Rg19.28 Å
原子数2109
残基数256
排除体积37540 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 2p7p__assembly_1__model_1 dimeric (2) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
2 1 2p7p__assembly_2__model_1 dimeric (2) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
3 1 2p7p__assembly_3__model_1 dimeric (2) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
4 1 2p7p__assembly_4__model_1 hexameric (6) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (4)

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6. 折叠分类 (SCOP + CATH) 12 domains

SCOP 2.08 (6 domains)

结构域编号 domain_idd2p7pa_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.32 — Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
超家族 Superfamily superfamilyd.32.1 — Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
家族 Family familyd.32.1.2 — Antibiotic resistance proteins
结构域编号 domain_idd2p7pb_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.32 — Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
超家族 Superfamily superfamilyd.32.1 — Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
家族 Family familyd.32.1.2 — Antibiotic resistance proteins
结构域编号 domain_idd2p7pc_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.32 — Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
超家族 Superfamily superfamilyd.32.1 — Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
家族 Family familyd.32.1.2 — Antibiotic resistance proteins
结构域编号 domain_idd2p7pd_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.32 — Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
超家族 Superfamily superfamilyd.32.1 — Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
家族 Family familyd.32.1.2 — Antibiotic resistance proteins
结构域编号 domain_idd2p7pe_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.32 — Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
超家族 Superfamily superfamilyd.32.1 — Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
家族 Family familyd.32.1.2 — Antibiotic resistance proteins
结构域编号 domain_idd2p7pf_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.32 — Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
超家族 Superfamily superfamilyd.32.1 — Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
家族 Family familyd.32.1.2 — Antibiotic resistance proteins

CATH v4.4 (6 domains)

结构域编号 domain_id2p7pA00
类 Class class3 — Alpha Beta
架构 Architecture architecture10 — Roll
拓扑 Topology topology180 — 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1
同源超家族 H-superfamily homologous superfamily10 — 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1
结构域编号 domain_id2p7pB00
类 Class class3 — Alpha Beta
架构 Architecture architecture10 — Roll
拓扑 Topology topology180 — 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1
同源超家族 H-superfamily homologous superfamily10 — 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1
结构域编号 domain_id2p7pC00
类 Class class3 — Alpha Beta
架构 Architecture architecture10 — Roll
拓扑 Topology topology180 — 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1
同源超家族 H-superfamily homologous superfamily10 — 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1
结构域编号 domain_id2p7pD00
类 Class class3 — Alpha Beta
架构 Architecture architecture10 — Roll
拓扑 Topology topology180 — 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1
同源超家族 H-superfamily homologous superfamily10 — 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1
结构域编号 domain_id2p7pE00
类 Class class3 — Alpha Beta
架构 Architecture architecture10 — Roll
拓扑 Topology topology180 — 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1
同源超家族 H-superfamily homologous superfamily10 — 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1
结构域编号 domain_id2p7pF00
类 Class class3 — Alpha Beta
架构 Architecture architecture10 — Roll
拓扑 Topology topology180 — 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1
同源超家族 H-superfamily homologous superfamily10 — 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1
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7. 引用文献 (1)