2p9k

Crystal structure of bovine Arp2/3 complex co-crystallized with ATP and crosslinked with glutaraldehyde

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Actin-like protein 3

Bos taurus

UniProt P61157

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 7 Actin-like protein 2 × 1 (A7MB62) Actin-related protein 2/3 complex subunit 1B × 1 (Q58CQ2) Actin-related protein 2/3 complex subunit 2 × 1 (Q3MHR7) Actin-related protein 2/3 complex subunit 3 × 1 (Q3T035) Actin-related protein 2/3 complex subunit 4 × 1 (Q148J6) Actin-related protein 2/3 complex subunit 5 × 1 (Q3SYX9) CALCIUM ION × 2 ADENOSINE-5'-TRIPHOSPHATE × 2 water × 7 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 ARP3_BOVIN
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 1–418; UniProt 1–418

Actin-like protein 2

Bos taurus

UniProt A7MB62

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 7 Actin-like protein 3 × 1 (P61157) Actin-related protein 2/3 complex subunit 1B × 1 (Q58CQ2) Actin-related protein 2/3 complex subunit 2 × 1 (Q3MHR7) Actin-related protein 2/3 complex subunit 3 × 1 (Q3T035) Actin-related protein 2/3 complex subunit 4 × 1 (Q148J6) Actin-related protein 2/3 complex subunit 5 × 1 (Q3SYX9) CALCIUM ION × 2 ADENOSINE-5'-TRIPHOSPHATE × 2 water × 7 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 ARP2_BOVIN
Isoform —
PDB实体 2
链与序列区间 作者链 B; PDB构建体 1–394; UniProt 1–394

Actin-related protein 2/3 complex subunit 1B

Bos taurus

UniProt Q58CQ2

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 7 Actin-like protein 3 × 1 (P61157) Actin-like protein 2 × 1 (A7MB62) Actin-related protein 2/3 complex subunit 2 × 1 (Q3MHR7) Actin-related protein 2/3 complex subunit 3 × 1 (Q3T035) Actin-related protein 2/3 complex subunit 4 × 1 (Q148J6) Actin-related protein 2/3 complex subunit 5 × 1 (Q3SYX9) CALCIUM ION × 2 ADENOSINE-5'-TRIPHOSPHATE × 2 water × 7 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 ARC1B_BOVIN
Isoform —
PDB实体 3
链与序列区间 作者链 C; PDB构建体 1–372; UniProt 1–372

Actin-related protein 2/3 complex subunit 2

Bos taurus

UniProt Q3MHR7

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 7 Actin-like protein 3 × 1 (P61157) Actin-like protein 2 × 1 (A7MB62) Actin-related protein 2/3 complex subunit 1B × 1 (Q58CQ2) Actin-related protein 2/3 complex subunit 3 × 1 (Q3T035) Actin-related protein 2/3 complex subunit 4 × 1 (Q148J6) Actin-related protein 2/3 complex subunit 5 × 1 (Q3SYX9) CALCIUM ION × 2 ADENOSINE-5'-TRIPHOSPHATE × 2 water × 7 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 ARPC2_BOVIN
Isoform —
PDB实体 4
链与序列区间 作者链 D; PDB构建体 1–300; UniProt 1–300

Actin-related protein 2/3 complex subunit 3

Bos taurus

UniProt Q3T035

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 7 Actin-like protein 3 × 1 (P61157) Actin-like protein 2 × 1 (A7MB62) Actin-related protein 2/3 complex subunit 1B × 1 (Q58CQ2) Actin-related protein 2/3 complex subunit 2 × 1 (Q3MHR7) Actin-related protein 2/3 complex subunit 4 × 1 (Q148J6) Actin-related protein 2/3 complex subunit 5 × 1 (Q3SYX9) CALCIUM ION × 2 ADENOSINE-5'-TRIPHOSPHATE × 2 water × 7 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 ARPC3_BOVIN
Isoform —
PDB实体 5
链与序列区间 作者链 E; PDB构建体 1–178; UniProt 1–178

Actin-related protein 2/3 complex subunit 4

Bos taurus

UniProt Q148J6

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 7 Actin-like protein 3 × 1 (P61157) Actin-like protein 2 × 1 (A7MB62) Actin-related protein 2/3 complex subunit 1B × 1 (Q58CQ2) Actin-related protein 2/3 complex subunit 2 × 1 (Q3MHR7) Actin-related protein 2/3 complex subunit 3 × 1 (Q3T035) Actin-related protein 2/3 complex subunit 5 × 1 (Q3SYX9) CALCIUM ION × 2 ADENOSINE-5'-TRIPHOSPHATE × 2 water × 7 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 ARPC4_BOVIN
Isoform —
PDB实体 6
链与序列区间 作者链 F; PDB构建体 1–168; UniProt 1–168

Actin-related protein 2/3 complex subunit 5

Bos taurus

UniProt Q3SYX9

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 7 Actin-like protein 3 × 1 (P61157) Actin-like protein 2 × 1 (A7MB62) Actin-related protein 2/3 complex subunit 1B × 1 (Q58CQ2) Actin-related protein 2/3 complex subunit 2 × 1 (Q3MHR7) Actin-related protein 2/3 complex subunit 3 × 1 (Q3T035) Actin-related protein 2/3 complex subunit 4 × 1 (Q148J6) CALCIUM ION × 2 ADENOSINE-5'-TRIPHOSPHATE × 2 water × 7 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 ARPC5_BOVIN
Isoform —
PDB实体 7
链与序列区间 作者链 G; PDB构建体 1–151; UniProt 1–151

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id2p9k
沉积日期 deposition_date2007-03-26
结构标题 titleCrystal structure of bovine Arp2/3 complex co-crystallized with ATP and crosslinked with glutaraldehyde
关键词 keywordscomplex, actin, WD repeat, STRUCTURAL PROTEIN; STRUCTURAL PROTEIN
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

2p9k__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

2p9k__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

2p9k__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)43.47 Å
Rg(电子密度)43.04 Å
总 Rg43.28 Å
原子数13964
残基数1763
排除体积248630 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 2p9k__assembly_1__model_1 heptameric (7) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (10)

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6. 折叠分类 (SCOP + CATH) 20 domains

SCOP 2.08 (8 domains)

结构域编号 domain_idd2p9ka1
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.55 — Ribonuclease H-like motif
超家族 Superfamily superfamilyc.55.1 — Actin-like ATPase domain
家族 Family familyc.55.1.1 — Actin/HSP70
结构域编号 domain_idd2p9ka2
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.55 — Ribonuclease H-like motif
超家族 Superfamily superfamilyc.55.1 — Actin-like ATPase domain
家族 Family familyc.55.1.1 — Actin/HSP70
结构域编号 domain_idd2p9kc_
类 Class classb — All beta proteins
折叠类型 Fold foldb.69 — 7-bladed beta-propeller
超家族 Superfamily superfamilyb.69.4 — WD40 repeat-like
家族 Family familyb.69.4.1 — WD40-repeat
结构域编号 domain_idd2p9kd1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.198 — Secretion chaperone-like
超家族 Superfamily superfamilyd.198.2 — Arp2/3 complex subunits
家族 Family familyd.198.2.1 — Arp2/3 complex subunits
结构域编号 domain_idd2p9kd2
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.198 — Secretion chaperone-like
超家族 Superfamily superfamilyd.198.2 — Arp2/3 complex subunits
家族 Family familyd.198.2.1 — Arp2/3 complex subunits
结构域编号 domain_idd2p9ke_
类 Class classa — All alpha proteins
折叠类型 Fold folda.148 — Arp2/3 complex 21 kDa subunit ARPC3
超家族 Superfamily superfamilya.148.1 — Arp2/3 complex 21 kDa subunit ARPC3
家族 Family familya.148.1.1 — Arp2/3 complex 21 kDa subunit ARPC3
结构域编号 domain_idd2p9kf_
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.198 — Secretion chaperone-like
超家族 Superfamily superfamilyd.198.2 — Arp2/3 complex subunits
家族 Family familyd.198.2.1 — Arp2/3 complex subunits
结构域编号 domain_idd2p9kg_
类 Class classa — All alpha proteins
折叠类型 Fold folda.118 — alpha-alpha superhelix
超家族 Superfamily superfamilya.118.13 — Arp2/3 complex 16 kDa subunit ARPC5
家族 Family familya.118.13.1 — Arp2/3 complex 16 kDa subunit ARPC5

CATH v4.4 (12 domains)

结构域编号 domain_id2p9kA01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology420 — Nucleotidyltransferase; domain 5
同源超家族 H-superfamily homologous superfamily40 — ATPase, nucleotide binding domain
结构域编号 domain_id2p9kA02
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology420 — Nucleotidyltransferase; domain 5
同源超家族 H-superfamily homologous superfamily40 — ATPase, nucleotide binding domain
结构域编号 domain_id2p9kA03
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology640 — Actin; Chain A, domain 4
同源超家族 H-superfamily homologous superfamily10 — ATPase, substrate binding domain, subdomain 4
结构域编号 domain_id2p9kB01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology420 — Nucleotidyltransferase; domain 5
同源超家族 H-superfamily homologous superfamily40 — ATPase, nucleotide binding domain
结构域编号 domain_id2p9kB02
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology420 — Nucleotidyltransferase; domain 5
同源超家族 H-superfamily homologous superfamily40 — ATPase, nucleotide binding domain
结构域编号 domain_id2p9kB03
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology640 — Actin; Chain A, domain 4
同源超家族 H-superfamily homologous superfamily10 — ATPase, substrate binding domain, subdomain 4
结构域编号 domain_id2p9kC00
类 Class class2 — Mainly Beta
架构 Architecture architecture130 — 7 Propeller
拓扑 Topology topology10 — Methylamine Dehydrogenase; Chain H
同源超家族 H-superfamily homologous superfamily10 — YVTN repeat-like/Quinoprotein amine dehydrogenase
结构域编号 domain_id2p9kD01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1460 — Yope Regulator; Chain: A,
同源超家族 H-superfamily homologous superfamily20 —
结构域编号 domain_id2p9kD02
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1460 — Yope Regulator; Chain: A,
同源超家族 H-superfamily homologous superfamily20 —
结构域编号 domain_id2p9kE00
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology1760 — Arp2/3 complex 21 kDa subunit ARPC3
同源超家族 H-superfamily homologous superfamily10 — Actin-related protein 2/3 complex subunit 3
结构域编号 domain_id2p9kF00
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology1460 — Yope Regulator; Chain: A,
同源超家族 H-superfamily homologous superfamily20 —
结构域编号 domain_id2p9kG00
类 Class class1 — Mainly Alpha
架构 Architecture architecture25 — Alpha Horseshoe
拓扑 Topology topology40 — Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
同源超家族 H-superfamily homologous superfamily190 — Actin-related protein 2/3 complex subunit 5
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7. 引用文献 (1)