SAXSdb — 2pzx

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1. Protein Identity and Related Structures Protein Identity & Related Structures

G-protein coupled receptor Mth

Drosophila melanogaster

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein monomer	Monomer	Protein 1	No other associated polymer	Consistent with protein count
2	Protein monomer	Monomer	Protein 1	No other associated polymer	Consistent with protein count
3	Protein monomer	Monomer	Protein 1	No other associated polymer	Consistent with protein count
4	Protein monomer	Monomer	Protein 1	No other associated polymer	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	MTH_DROME
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–188； UniProt 25–212 Author chain B； PDBConstruct 1–188； UniProt 25–212 Author chain C； PDBConstruct 1–188； UniProt 25–212 Author chain D； PDBConstruct 1–188； UniProt 25–212

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	2pzx
Deposition date deposition_date	2007-05-18
Structure title title	Structure of the methuselah ectodomain with peptide inhibitor
Keywords keywords	GPCR G protein-coupled receptor ectodomain, SIGNALING PROTEIN; SIGNALING PROTEIN
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2pzx__assembly_3__model_1

Assembly 3 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2pzx__assembly_3__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

2pzx__assembly_3__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	18.08 Å
Rg (electron density)	17.08 Å
Total Rg	17.98 Å
Atom count	1529
Residues	188
Excluded volume	27012 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`2pzx__assembly_1__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`2pzx__assembly_2__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	1	`2pzx__assembly_3__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	1	`2pzx__assembly_4__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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6. Fold Classification (SCOP + CATH) 12 domains

SCOP 2.08 (4 domains)

Domain ID domain_id	d2pzxa1
Class class	b — All beta proteins
Fold Fold fold	b.102 — Methuselah ectodomain
Superfamily Superfamily superfamily	b.102.1 — Methuselah ectodomain
Family Family family	b.102.1.1 — Methuselah ectodomain

Domain ID domain_id	d2pzxb1
Class class	b — All beta proteins
Fold Fold fold	b.102 — Methuselah ectodomain
Superfamily Superfamily superfamily	b.102.1 — Methuselah ectodomain
Family Family family	b.102.1.1 — Methuselah ectodomain

Domain ID domain_id	d2pzxc1
Class class	b — All beta proteins
Fold Fold fold	b.102 — Methuselah ectodomain
Superfamily Superfamily superfamily	b.102.1 — Methuselah ectodomain
Family Family family	b.102.1.1 — Methuselah ectodomain

Domain ID domain_id	d2pzxd1
Class class	b — All beta proteins
Fold Fold fold	b.102 — Methuselah ectodomain
Superfamily Superfamily superfamily	b.102.1 — Methuselah ectodomain
Family Family family	b.102.1.1 — Methuselah ectodomain

CATH v4.4 (8 domains)

Domain ID domain_id	2pzxA01
Class class	2 — Mainly Beta
Architecture architecture	30 — Roll
Topology topology	160 — Methuselah Ectodomain; Chain: A, domain 1
Homologous superfamily homologous superfamily	11 —

Domain ID domain_id	2pzxA02
Class class	2 — Mainly Beta
Architecture architecture	170 — Beta Complex
Topology topology	180 — Methuselah ectodomain, domain 2
Homologous superfamily homologous superfamily	11 — Methuselah ectodomain, domain 2

Domain ID domain_id	2pzxB01
Class class	2 — Mainly Beta
Architecture architecture	30 — Roll
Topology topology	160 — Methuselah Ectodomain; Chain: A, domain 1
Homologous superfamily homologous superfamily	11 —

Domain ID domain_id	2pzxB02
Class class	2 — Mainly Beta
Architecture architecture	170 — Beta Complex
Topology topology	180 — Methuselah ectodomain, domain 2
Homologous superfamily homologous superfamily	11 — Methuselah ectodomain, domain 2

Domain ID domain_id	2pzxC01
Class class	2 — Mainly Beta
Architecture architecture	30 — Roll
Topology topology	160 — Methuselah Ectodomain; Chain: A, domain 1
Homologous superfamily homologous superfamily	11 —

Domain ID domain_id	2pzxC02
Class class	2 — Mainly Beta
Architecture architecture	170 — Beta Complex
Topology topology	180 — Methuselah ectodomain, domain 2
Homologous superfamily homologous superfamily	11 — Methuselah ectodomain, domain 2

Domain ID domain_id	2pzxD01
Class class	2 — Mainly Beta
Architecture architecture	30 — Roll
Topology topology	160 — Methuselah Ectodomain; Chain: A, domain 1
Homologous superfamily homologous superfamily	11 —

Domain ID domain_id	2pzxD02
Class class	2 — Mainly Beta
Architecture architecture	170 — Beta Complex
Topology topology	180 — Methuselah ectodomain, domain 2
Homologous superfamily homologous superfamily	11 — Methuselah ectodomain, domain 2

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Unit-cell length a length_a	94.233 Å
Unit-cell length b length_b	94.233 Å
Unit-cell length c length_c	173.833 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	16

Space group space_group	P 42
Space-group number int_tables_number	77
Crystal system crystal_system	—

Resolution resolution	3.500 Å
Low-resolution limit resolution_low	7.990 Å
R factor r_factor	0.3760
R_work r_work	0.3760
R_free r_free	0.4070

Description description	G-protein coupled receptor Mth
Molecular weight formula_weight	21835.8 kDa
Source method src_method	man
Copy count entity_count	4

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D
Atom count atom_count	9174

Structure of the methuselah ectodomain with peptide inhibitor

1. Protein Identity and Related Structures Protein Identity & Related Structures

G-protein coupled receptor Mth

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2pzx__assembly_3__model_1

2pzx__assembly_3__model_1 | I(q)

2pzx__assembly_3__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

6. Fold Classification (SCOP + CATH) 12 domains

SCOP 2.08 (4 domains)

CATH v4.4 (8 domains)

7. Citations (1)

Source organism organism	Drosophila melanogaster
Common name common_name	fruit fly
NCBI taxonomy ID ncbi_taxonomy_id	7227
Host organism host_organism	unidentified baculovirus

Structure of the methuselah ectodomain with peptide inhibitor

1. Protein Identity and Related Structures Protein Identity & Related Structures

G-protein coupled receptor Mth

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2pzx__assembly_3__model_1

2pzx__assembly_3__model_1 | I(q)

2pzx__assembly_3__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

6. Fold Classification (SCOP + CATH) 12 domains

SCOP 2.08 (4 domains)

CATH v4.4 (8 domains)

7. Citations (1)