2q4k

Ensemble refinement of the protein crystal structure of gene product from Homo sapiens Hs.433573

Method: X-RAY DIFFRACTION

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Uncharacterized protein C11orf68

Homo sapiens

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
2	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
3	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
4	Protein homooligomer	Homooligomer	Protein 2	water × 2	Consistent with protein count
5	Protein homooligomer	Homooligomer	Protein 2	water × 2	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	CK068_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–251； UniProt 1–251 Author chain B； PDBConstruct 1–251； UniProt 1–251 Author chain C； PDBConstruct 1–251； UniProt 1–251

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	2q4k
Deposition date deposition_date	2007-05-31
Structure title title	Ensemble refinement of the protein crystal structure of gene product from Homo sapiens Hs.433573
Keywords keywords	;Ensemble Refinement, Refinement Methodology Development, Hs.433573, P5326, BLES03, BC010512, Structural Genomics, Protein Structure Initiative, PSI, Center for Eukaryotic Structural Genomics, CESG, UNKNOWN FUNCTION ;; STRUCTURAL GENOMICS, UNKNOWN FUNCTION
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2q4k__assembly_1__model_14

Assembly 1 · Model 14 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2q4k__assembly_1__model_14 | I(q)

100 plotted points; both axes use logarithmic scales.

2q4k__assembly_1__model_14 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	20.26 Å
Rg (electron density)	19.12 Å
Total Rg	20.02 Å
Atom count	1769
Residues	225
Excluded volume	31302 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`2q4k__assembly_1__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	2	`2q4k__assembly_1__model_2`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	3	`2q4k__assembly_1__model_3`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	4	`2q4k__assembly_1__model_4`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	5	`2q4k__assembly_1__model_5`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	6	`2q4k__assembly_1__model_6`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	7	`2q4k__assembly_1__model_7`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	8	`2q4k__assembly_1__model_8`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	9	`2q4k__assembly_1__model_9`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	10	`2q4k__assembly_1__model_10`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	11	`2q4k__assembly_1__model_11`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	12	`2q4k__assembly_1__model_12`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	13	`2q4k__assembly_1__model_13`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	14	`2q4k__assembly_1__model_14`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	15	`2q4k__assembly_1__model_15`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	16	`2q4k__assembly_1__model_16`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`2q4k__assembly_2__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	2	`2q4k__assembly_2__model_2`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	3	`2q4k__assembly_2__model_3`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	4	`2q4k__assembly_2__model_4`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	5	`2q4k__assembly_2__model_5`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	6	`2q4k__assembly_2__model_6`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	7	`2q4k__assembly_2__model_7`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	8	`2q4k__assembly_2__model_8`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	9	`2q4k__assembly_2__model_9`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	10	`2q4k__assembly_2__model_10`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	11	`2q4k__assembly_2__model_11`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	12	`2q4k__assembly_2__model_12`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	13	`2q4k__assembly_2__model_13`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	14	`2q4k__assembly_2__model_14`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	15	`2q4k__assembly_2__model_15`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	16	`2q4k__assembly_2__model_16`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	1	`2q4k__assembly_3__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	2	`2q4k__assembly_3__model_2`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	3	`2q4k__assembly_3__model_3`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	4	`2q4k__assembly_3__model_4`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	5	`2q4k__assembly_3__model_5`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	6	`2q4k__assembly_3__model_6`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	7	`2q4k__assembly_3__model_7`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	8	`2q4k__assembly_3__model_8`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	9	`2q4k__assembly_3__model_9`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	10	`2q4k__assembly_3__model_10`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	11	`2q4k__assembly_3__model_11`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	12	`2q4k__assembly_3__model_12`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	13	`2q4k__assembly_3__model_13`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	14	`2q4k__assembly_3__model_14`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	15	`2q4k__assembly_3__model_15`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	16	`2q4k__assembly_3__model_16`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	1	`2q4k__assembly_4__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	2	`2q4k__assembly_4__model_2`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	3	`2q4k__assembly_4__model_3`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	4	`2q4k__assembly_4__model_4`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	5	`2q4k__assembly_4__model_5`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	6	`2q4k__assembly_4__model_6`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	7	`2q4k__assembly_4__model_7`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	8	`2q4k__assembly_4__model_8`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	9	`2q4k__assembly_4__model_9`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	10	`2q4k__assembly_4__model_10`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	11	`2q4k__assembly_4__model_11`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	12	`2q4k__assembly_4__model_12`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	13	`2q4k__assembly_4__model_13`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	14	`2q4k__assembly_4__model_14`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	15	`2q4k__assembly_4__model_15`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	16	`2q4k__assembly_4__model_16`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	1	`2q4k__assembly_5__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	2	`2q4k__assembly_5__model_2`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	3	`2q4k__assembly_5__model_3`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	4	`2q4k__assembly_5__model_4`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	5	`2q4k__assembly_5__model_5`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	6	`2q4k__assembly_5__model_6`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	7	`2q4k__assembly_5__model_7`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	8	`2q4k__assembly_5__model_8`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	9	`2q4k__assembly_5__model_9`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	10	`2q4k__assembly_5__model_10`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	11	`2q4k__assembly_5__model_11`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	12	`2q4k__assembly_5__model_12`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	13	`2q4k__assembly_5__model_13`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	14	`2q4k__assembly_5__model_14`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	15	`2q4k__assembly_5__model_15`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	16	`2q4k__assembly_5__model_16`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 6 domains

SCOP 2.08 (3 domains)

Domain ID domain_id	d2q4ka_
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.86 — eIF4e-like
Superfamily Superfamily superfamily	d.86.1 — eIF4e-like
Family Family family	d.86.1.2 — BLES03-like

Domain ID domain_id	d2q4kb_
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.86 — eIF4e-like
Superfamily Superfamily superfamily	d.86.1 — eIF4e-like
Family Family family	d.86.1.2 — BLES03-like

Domain ID domain_id	d2q4kc_
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.86 — eIF4e-like
Superfamily Superfamily superfamily	d.86.1 — eIF4e-like
Family Family family	d.86.1.2 — BLES03-like

CATH v4.4 (3 domains)

Domain ID domain_id	2q4kA01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	760 — RNA Cap, Translation Initiation Factor Eif4e
Homologous superfamily homologous superfamily	10 — RNA Cap, Translation Initiation Factor Eif4e

Domain ID domain_id	2q4kB01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	760 — RNA Cap, Translation Initiation Factor Eif4e
Homologous superfamily homologous superfamily	10 — RNA Cap, Translation Initiation Factor Eif4e

Domain ID domain_id	2q4kC00
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	760 — RNA Cap, Translation Initiation Factor Eif4e
Homologous superfamily homologous superfamily	10 — RNA Cap, Translation Initiation Factor Eif4e

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Unit-cell length a length_a	62.547 Å
Unit-cell length b length_b	116.809 Å
Unit-cell length c length_c	123.635 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	12

Space group space_group	P 21 21 21
Space-group number int_tables_number	19
Crystal system crystal_system	—

Resolution resolution	2.500 Å
Low-resolution limit resolution_low	43.970 Å
R factor r_factor	0.1660
R_work r_work	0.1660
R_free r_free	0.2360

Description description	Uncharacterized protein C11orf68
Molecular weight formula_weight	27600.3 kDa
Source method src_method	man
Copy count entity_count	3

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C
Atom count atom_count	88208

Ensemble refinement of the protein crystal structure of gene product from Homo sapiens Hs.433573

1. Protein Identity and Related Structures Protein Identity & Related Structures

Uncharacterized protein C11orf68

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2q4k__assembly_1__model_14

2q4k__assembly_1__model_14 | I(q)

2q4k__assembly_1__model_14 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 water

6. Fold Classification (SCOP + CATH) 6 domains

SCOP 2.08 (3 domains)

CATH v4.4 (3 domains)

7. Citations (2)

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Escherichia coli

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	217

Ensemble refinement of the protein crystal structure of gene product from Homo sapiens Hs.433573

1. Protein Identity and Related Structures Protein Identity & Related Structures

Uncharacterized protein C11orf68

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2q4k__assembly_1__model_14

2q4k__assembly_1__model_14 | I(q)

2q4k__assembly_1__model_14 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 water

6. Fold Classification (SCOP + CATH) 6 domains

SCOP 2.08 (3 domains)

CATH v4.4 (3 domains)

7. Citations (2)