Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白单体 | 单体 | 蛋白 1 | CHLORIDE ION × 1 SULFATE ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GLYCEROL × 2 water × 1 | 与蛋白数一致 |
| 2 | 蛋白单体 | 单体 | 蛋白 1 | CHLORIDE ION × 1 SULFATE ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GLYCEROL × 2 water × 1 | 与蛋白数一致 |
| UniProt名称 | PUR2_HUMAN |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 23–452； UniProt 1–430 作者链 B； PDB构建体 23–452； UniProt 1–430 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 2qk4 |
| 沉积日期 deposition_date | 2007-07-10 |
| 结构标题 title | Human glycinamide ribonucleotide synthetase |
| 关键词 keywords | PURINE SYNTHESIS, ENZYME, PROTEIN-ATP COMPLEX, Structural Genomics, Structural Genomics Consortium, SGC, LIGASE; LIGASE |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 22.47 Å |
| Rg（电子密度） | 21.44 Å |
| 总 Rg | 22.38 Å |
| 原子数 | 3194 |
| 残基数 | 424 |
| 排除体积 | 57122 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d2qk4a1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.30 — PreATP-grasp domain |
| 超家族 Superfamily superfamily | c.30.1 — PreATP-grasp domain |
| 家族 Family family | c.30.1.0 — automated matches |
| 结构域编号 domain_id | d2qk4a2 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.142 — ATP-grasp |
| 超家族 Superfamily superfamily | d.142.1 — Glutathione synthetase ATP-binding domain-like |
| 家族 Family family | d.142.1.0 — automated matches |
| 结构域编号 domain_id | d2qk4a3 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.84 — Barrel-sandwich hybrid |
| 超家族 Superfamily superfamily | b.84.2 — Rudiment single hybrid motif |
| 家族 Family family | b.84.2.0 — automated matches |
| 结构域编号 domain_id | d2qk4a4 |
| 类 Class class | l — Artifacts |
| 折叠类型 Fold fold | l.1 — Tags |
| 超家族 Superfamily superfamily | l.1.1 — Tags |
| 家族 Family family | l.1.1.1 — Tags |
| 结构域编号 domain_id | d2qk4b1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.30 — PreATP-grasp domain |
| 超家族 Superfamily superfamily | c.30.1 — PreATP-grasp domain |
| 家族 Family family | c.30.1.0 — automated matches |
| 结构域编号 domain_id | d2qk4b2 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.142 — ATP-grasp |
| 超家族 Superfamily superfamily | d.142.1 — Glutathione synthetase ATP-binding domain-like |
| 家族 Family family | d.142.1.0 — automated matches |
| 结构域编号 domain_id | d2qk4b3 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.84 — Barrel-sandwich hybrid |
| 超家族 Superfamily superfamily | b.84.2 — Rudiment single hybrid motif |
| 家族 Family family | b.84.2.0 — automated matches |
| 结构域编号 domain_id | d2qk4b4 |
| 类 Class class | l — Artifacts |
| 折叠类型 Fold fold | l.1 — Tags |
| 超家族 Superfamily superfamily | l.1.1 — Tags |
| 家族 Family family | l.1.1.1 — Tags |
| 结构域编号 domain_id | 2qk4A01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 20 — |
| 结构域编号 domain_id | 2qk4A02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 1490 — Dna Ligase; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 20 — ATP-grasp fold, A domain |
| 结构域编号 domain_id | 2qk4A03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 470 — D-amino Acid Aminotransferase; Chain A, domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 20 — ATP-grasp fold, B domain |
| 结构域编号 domain_id | 2qk4A04 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 600 — Glycinamide Ribonucleotide Synthetase; Chain A, domain 4 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Phosphoribosylglycinamide synthetase, C-terminal domain |
| 结构域编号 domain_id | 2qk4B01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 20 — |
| 结构域编号 domain_id | 2qk4B02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 1490 — Dna Ligase; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 20 — ATP-grasp fold, A domain |
| 结构域编号 domain_id | 2qk4B03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 470 — D-amino Acid Aminotransferase; Chain A, domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 20 — ATP-grasp fold, B domain |
| 结构域编号 domain_id | 2qk4B04 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 600 — Glycinamide Ribonucleotide Synthetase; Chain A, domain 4 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Phosphoribosylglycinamide synthetase, C-terminal domain |