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2qts

Structure of an acid-sensing ion channel 1 at 1.9 A resolution and low pH

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Acid-sensing ion channel

Gallus gallus

UniProt Q1XA76

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Homooligomer Protein 3 其他Polymer 3 alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 CHLORIDE ION × 3 water × 3 Consistent with protein count
2 Protein homooligomer Homooligomer Protein 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 CHLORIDE ION × 3 water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
7lie

1 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers
2qts 3ij4 4nyk 6ave 6cmc 6vtk 6vtl 6x9h

8 assemblies

Heteromeric or nucleic-acid complex
2qts 3s3w 3s3x 4fz0 4fz1 4ntw 4ntw 4ntx 4ntx 4nty 5wku 5wkv

14 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name Q1XA76_CHICK
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–438； UniProt 26–463 Author chain B； PDBConstruct 1–438； UniProt 26–463 Author chain C； PDBConstruct 1–438； UniProt 26–463 Author chain D； PDBConstruct 1–438； UniProt 26–463 Author chain E； PDBConstruct 1–438； UniProt 26–463 Author chain F； PDBConstruct 1–438； UniProt 26–463

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2qts
Deposition date deposition_date2007-08-02
Structure title titleStructure of an acid-sensing ion channel 1 at 1.9 A resolution and low pH
Keywords keywordsacid-sensing, ion channel, trimer, MEMBRANE PROTEIN; MEMBRANE PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2qts__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2qts__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2qts__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）36.36 Å
Rg (electron density)36.85 Å
Total Rg37.10 Å
Atom count10220
Residues1255
Excluded volume182600 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2qts__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 2qts__assembly_2__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

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6. Fold Classification (SCOP + CATH) 24 domains

CATH v4.4 (24 domains)

Domain ID domain_id2qtsA01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily770 — YojJ-like
Domain ID domain_id2qtsA02
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology470 — Acid-sensing ion channels like fold
Homologous superfamily homologous superfamily10 — Acid-sensing ion channels like domains
Domain ID domain_id2qtsA03
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology3590 — acid-sensing ion channel 1 fold
Homologous superfamily homologous superfamily10 — acid-sensing ion channel 1 domain
Domain ID domain_id2qtsA04
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily820 — Acid-sensing ion channel domain
Domain ID domain_id2qtsB01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily770 — YojJ-like
Domain ID domain_id2qtsB02
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology470 — Acid-sensing ion channels like fold
Homologous superfamily homologous superfamily10 — Acid-sensing ion channels like domains
Domain ID domain_id2qtsB03
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology3590 — acid-sensing ion channel 1 fold
Homologous superfamily homologous superfamily10 — acid-sensing ion channel 1 domain
Domain ID domain_id2qtsB04
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily820 — Acid-sensing ion channel domain
Domain ID domain_id2qtsC01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily770 — YojJ-like
Domain ID domain_id2qtsC02
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology470 — Acid-sensing ion channels like fold
Homologous superfamily homologous superfamily10 — Acid-sensing ion channels like domains
Domain ID domain_id2qtsC03
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology3590 — acid-sensing ion channel 1 fold
Homologous superfamily homologous superfamily10 — acid-sensing ion channel 1 domain
Domain ID domain_id2qtsC04
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily820 — Acid-sensing ion channel domain
Domain ID domain_id2qtsD01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily770 — YojJ-like
Domain ID domain_id2qtsD02
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology470 — Acid-sensing ion channels like fold
Homologous superfamily homologous superfamily10 — Acid-sensing ion channels like domains
Domain ID domain_id2qtsD03
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology3590 — acid-sensing ion channel 1 fold
Homologous superfamily homologous superfamily10 — acid-sensing ion channel 1 domain
Domain ID domain_id2qtsD04
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily820 — Acid-sensing ion channel domain
Domain ID domain_id2qtsE01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily770 — YojJ-like
Domain ID domain_id2qtsE02
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology470 — Acid-sensing ion channels like fold
Homologous superfamily homologous superfamily10 — Acid-sensing ion channels like domains
Domain ID domain_id2qtsE03
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology3590 — acid-sensing ion channel 1 fold
Homologous superfamily homologous superfamily10 — acid-sensing ion channel 1 domain
Domain ID domain_id2qtsE04
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily820 — Acid-sensing ion channel domain
Domain ID domain_id2qtsF01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily770 — YojJ-like
Domain ID domain_id2qtsF02
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology470 — Acid-sensing ion channels like fold
Homologous superfamily homologous superfamily10 — Acid-sensing ion channels like domains
Domain ID domain_id2qtsF03
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology3590 — acid-sensing ion channel 1 fold
Homologous superfamily homologous superfamily10 — acid-sensing ion channel 1 domain
Domain ID domain_id2qtsF04
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily820 — Acid-sensing ion channel domain
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7. Citations (1)