2qts

Structure of an acid-sensing ion channel 1 at 1.9 A resolution and low pH

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Acid-sensing ion channel

Gallus gallus

UniProt Q1XA76

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 其他组合 同源多聚体 蛋白 3 其他聚合物 3 alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 CHLORIDE ION × 3 water × 3 与蛋白数一致
2 蛋白同源多聚体 同源多聚体 蛋白 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 CHLORIDE ION × 3 water × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 Q1XA76_CHICK
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 1–438; UniProt 26–463 作者链 B; PDB构建体 1–438; UniProt 26–463 作者链 C; PDB构建体 1–438; UniProt 26–463 作者链 D; PDB构建体 1–438; UniProt 26–463 作者链 E; PDB构建体 1–438; UniProt 26–463 作者链 F; PDB构建体 1–438; UniProt 26–463

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id2qts
沉积日期 deposition_date2007-08-02
结构标题 titleStructure of an acid-sensing ion channel 1 at 1.9 A resolution and low pH
关键词 keywordsacid-sensing, ion channel, trimer, MEMBRANE PROTEIN; MEMBRANE PROTEIN
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

2qts__assembly_2__model_1

Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

2qts__assembly_2__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

2qts__assembly_2__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)36.04 Å
Rg(电子密度)36.48 Å
总 Rg36.80 Å
原子数10085
残基数1248
排除体积180200 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 2qts__assembly_1__model_1 trimeric (3) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
2 1 2qts__assembly_2__model_1 trimeric (3) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (5)

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6. 折叠分类 (SCOP + CATH) 24 domains

CATH v4.4 (24 domains)

结构域编号 domain_id2qtsA01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily770 — YojJ-like
结构域编号 domain_id2qtsA02
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology470 — Acid-sensing ion channels like fold
同源超家族 H-superfamily homologous superfamily10 — Acid-sensing ion channels like domains
结构域编号 domain_id2qtsA03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology3590 — acid-sensing ion channel 1 fold
同源超家族 H-superfamily homologous superfamily10 — acid-sensing ion channel 1 domain
结构域编号 domain_id2qtsA04
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily820 — Acid-sensing ion channel domain
结构域编号 domain_id2qtsB01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily770 — YojJ-like
结构域编号 domain_id2qtsB02
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology470 — Acid-sensing ion channels like fold
同源超家族 H-superfamily homologous superfamily10 — Acid-sensing ion channels like domains
结构域编号 domain_id2qtsB03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology3590 — acid-sensing ion channel 1 fold
同源超家族 H-superfamily homologous superfamily10 — acid-sensing ion channel 1 domain
结构域编号 domain_id2qtsB04
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily820 — Acid-sensing ion channel domain
结构域编号 domain_id2qtsC01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily770 — YojJ-like
结构域编号 domain_id2qtsC02
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology470 — Acid-sensing ion channels like fold
同源超家族 H-superfamily homologous superfamily10 — Acid-sensing ion channels like domains
结构域编号 domain_id2qtsC03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology3590 — acid-sensing ion channel 1 fold
同源超家族 H-superfamily homologous superfamily10 — acid-sensing ion channel 1 domain
结构域编号 domain_id2qtsC04
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily820 — Acid-sensing ion channel domain
结构域编号 domain_id2qtsD01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily770 — YojJ-like
结构域编号 domain_id2qtsD02
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology470 — Acid-sensing ion channels like fold
同源超家族 H-superfamily homologous superfamily10 — Acid-sensing ion channels like domains
结构域编号 domain_id2qtsD03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology3590 — acid-sensing ion channel 1 fold
同源超家族 H-superfamily homologous superfamily10 — acid-sensing ion channel 1 domain
结构域编号 domain_id2qtsD04
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily820 — Acid-sensing ion channel domain
结构域编号 domain_id2qtsE01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily770 — YojJ-like
结构域编号 domain_id2qtsE02
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology470 — Acid-sensing ion channels like fold
同源超家族 H-superfamily homologous superfamily10 — Acid-sensing ion channels like domains
结构域编号 domain_id2qtsE03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology3590 — acid-sensing ion channel 1 fold
同源超家族 H-superfamily homologous superfamily10 — acid-sensing ion channel 1 domain
结构域编号 domain_id2qtsE04
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily820 — Acid-sensing ion channel domain
结构域编号 domain_id2qtsF01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily770 — YojJ-like
结构域编号 domain_id2qtsF02
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology470 — Acid-sensing ion channels like fold
同源超家族 H-superfamily homologous superfamily10 — Acid-sensing ion channels like domains
结构域编号 domain_id2qtsF03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology3590 — acid-sensing ion channel 1 fold
同源超家族 H-superfamily homologous superfamily10 — acid-sensing ion channel 1 domain
结构域编号 domain_id2qtsF04
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily820 — Acid-sensing ion channel domain
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7. 引用文献 (1)