2uvo

High Resolution Crystal Structure of Wheat Germ Agglutinin in Complex with N-Acetyl-D-Glucosamine

Method: X-RAY DIFFRACTION

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1. 蛋白身份与相关结构 Protein Identity & Related Structures

AGGLUTININ ISOLECTIN 1

物种未注明

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	蛋白同源多聚体	同源多聚体	蛋白 2	2-acetamido-2-deoxy-alpha-D-glucopyranose × 5 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 GLYCEROL × 2 water × 2	与蛋白数一致
2	蛋白同源多聚体	同源多聚体	蛋白 2	2-acetamido-2-deoxy-alpha-D-glucopyranose × 4 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 GLYCEROL × 2 water × 2	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	AGI1_WHEAT
Isoform	—
PDB实体	1
链与序列区间	作者链 A； PDB构建体 1–171； UniProt 27–197 作者链 B； PDB构建体 1–171； UniProt 27–197 作者链 E； PDB构建体 1–171； UniProt 27–197 作者链 F； PDB构建体 1–171； UniProt 27–197

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id	2uvo
沉积日期 deposition_date	2007-03-13
结构标题 title	High Resolution Crystal Structure of Wheat Germ Agglutinin in Complex with N-Acetyl-D-Glucosamine
关键词 keywords	;CARBOHYDRATE-BINDING PROTEIN, HEVEIN DOMAIN, CHITIN-BINDING, WHEAT GERM AGGLUTININ, CHITIN-BINDING PROTEIN, N-ACETYL-D- GLUCOSAMINE, WGA, GLCNAC, CHITIN, LECTIN, ANTIFUNGAL, PROTEIN-CARBOHYDRATE INTERACTION ;; CARBOHYDRATE-BINDING PROTEIN
实验方法 method	X-RAY DIFFRACTION

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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

2uvo__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

2uvo__assembly_1__model_1 | I(q)

100 个绘图点；横轴和纵轴均采用对数尺度。

2uvo__assembly_1__model_1 | P(r) · Pending

P(r) 将按相同 assembly/model 分别计算和展示。

Rg（Guinier）	20.92 Å
Rg（电子密度）	20.48 Å
总 Rg	21.04 Å
原子数	2446
残基数	339
排除体积	41797 Å³
最大 q	0.500 Å⁻¹

Assembly	Model	结构单元	聚集说明	状态	CRYSOL	操作
1	1	`2uvo__assembly_1__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
2	1	`2uvo__assembly_2__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载

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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (5)

实体 1 Entity 1 polymer

描述 description	AGGLUTININ ISOLECTIN 1
分子量 formula_weight	17124.1 kDa
来源方法 src_method	nat
拷贝数 entity_count	4

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	A,B,E,F
原子数 atom_count	5652

QRCGEQGSNMECPNNLCCSQYGYCGMGGDYCGKGCQNGACWTSKRCGSQAGGATCTNNQCCSQYGYCGFGAEYCGAGCQGGPCRADIKCGSQAGGKLCPNNLCCSQWGFCGLGSEFCGGGCQSGACSTDKPCGKDAGGRVCTNNYCCSKWGSCGIGPGYCGAGCQSGGCDG

实体 2 Entity 2 non-polymer

描述 description	2-acetamido-2-deoxy-alpha-D-glucopyranose
分子量 formula_weight	221.2 kDa
来源方法 src_method	man
拷贝数 entity_count	9

实体 3 Entity 3 non-polymer

描述 description	2-acetamido-2-deoxy-beta-D-glucopyranose
分子量 formula_weight	221.2 kDa
来源方法 src_method	man
拷贝数 entity_count	9

实体 4 Entity 4 non-polymer

描述 description	GLYCEROL
分子量 formula_weight	92.1 kDa
来源方法 src_method	syn
拷贝数 entity_count	4

实体 5 Entity 5 water

描述 description	water
分子量 formula_weight	18.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	623

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6. 折叠分类 (SCOP + CATH) 32 domains

SCOP 2.08 (16 domains)

结构域编号 domain_id	d2uvoa1
类 Class class	g — Small proteins
折叠类型 Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
超家族 Superfamily superfamily	g.3.1 — Plant lectins/antimicrobial peptides
家族 Family family	g.3.1.1 — Hevein-like agglutinin (lectin) domain

结构域编号 domain_id	d2uvoa2
类 Class class	g — Small proteins
折叠类型 Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
超家族 Superfamily superfamily	g.3.1 — Plant lectins/antimicrobial peptides
家族 Family family	g.3.1.1 — Hevein-like agglutinin (lectin) domain

结构域编号 domain_id	d2uvoa3
类 Class class	g — Small proteins
折叠类型 Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
超家族 Superfamily superfamily	g.3.1 — Plant lectins/antimicrobial peptides
家族 Family family	g.3.1.1 — Hevein-like agglutinin (lectin) domain

结构域编号 domain_id	d2uvoa4
类 Class class	g — Small proteins
折叠类型 Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
超家族 Superfamily superfamily	g.3.1 — Plant lectins/antimicrobial peptides
家族 Family family	g.3.1.1 — Hevein-like agglutinin (lectin) domain

结构域编号 domain_id	d2uvob1
类 Class class	g — Small proteins
折叠类型 Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
超家族 Superfamily superfamily	g.3.1 — Plant lectins/antimicrobial peptides
家族 Family family	g.3.1.1 — Hevein-like agglutinin (lectin) domain

结构域编号 domain_id	d2uvob2
类 Class class	g — Small proteins
折叠类型 Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
超家族 Superfamily superfamily	g.3.1 — Plant lectins/antimicrobial peptides
家族 Family family	g.3.1.1 — Hevein-like agglutinin (lectin) domain

结构域编号 domain_id	d2uvob3
类 Class class	g — Small proteins
折叠类型 Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
超家族 Superfamily superfamily	g.3.1 — Plant lectins/antimicrobial peptides
家族 Family family	g.3.1.1 — Hevein-like agglutinin (lectin) domain

结构域编号 domain_id	d2uvob4
类 Class class	g — Small proteins
折叠类型 Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
超家族 Superfamily superfamily	g.3.1 — Plant lectins/antimicrobial peptides
家族 Family family	g.3.1.1 — Hevein-like agglutinin (lectin) domain

结构域编号 domain_id	d2uvoe1
类 Class class	g — Small proteins
折叠类型 Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
超家族 Superfamily superfamily	g.3.1 — Plant lectins/antimicrobial peptides
家族 Family family	g.3.1.1 — Hevein-like agglutinin (lectin) domain

结构域编号 domain_id	d2uvoe2
类 Class class	g — Small proteins
折叠类型 Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
超家族 Superfamily superfamily	g.3.1 — Plant lectins/antimicrobial peptides
家族 Family family	g.3.1.1 — Hevein-like agglutinin (lectin) domain

结构域编号 domain_id	d2uvoe3
类 Class class	g — Small proteins
折叠类型 Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
超家族 Superfamily superfamily	g.3.1 — Plant lectins/antimicrobial peptides
家族 Family family	g.3.1.1 — Hevein-like agglutinin (lectin) domain

结构域编号 domain_id	d2uvoe4
类 Class class	g — Small proteins
折叠类型 Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
超家族 Superfamily superfamily	g.3.1 — Plant lectins/antimicrobial peptides
家族 Family family	g.3.1.1 — Hevein-like agglutinin (lectin) domain

结构域编号 domain_id	d2uvof1
类 Class class	g — Small proteins
折叠类型 Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
超家族 Superfamily superfamily	g.3.1 — Plant lectins/antimicrobial peptides
家族 Family family	g.3.1.1 — Hevein-like agglutinin (lectin) domain

结构域编号 domain_id	d2uvof2
类 Class class	g — Small proteins
折叠类型 Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
超家族 Superfamily superfamily	g.3.1 — Plant lectins/antimicrobial peptides
家族 Family family	g.3.1.1 — Hevein-like agglutinin (lectin) domain

结构域编号 domain_id	d2uvof3
类 Class class	g — Small proteins
折叠类型 Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
超家族 Superfamily superfamily	g.3.1 — Plant lectins/antimicrobial peptides
家族 Family family	g.3.1.1 — Hevein-like agglutinin (lectin) domain

结构域编号 domain_id	d2uvof4
类 Class class	g — Small proteins
折叠类型 Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
超家族 Superfamily superfamily	g.3.1 — Plant lectins/antimicrobial peptides
家族 Family family	g.3.1.1 — Hevein-like agglutinin (lectin) domain

CATH v4.4 (16 domains)

结构域编号 domain_id	2uvoA01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	60 — Wheat Germ Agglutinin (Isolectin 2); domain 1
同源超家族 H-superfamily homologous superfamily	10 — Endochitinase-like

结构域编号 domain_id	2uvoA02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	60 — Wheat Germ Agglutinin (Isolectin 2); domain 1
同源超家族 H-superfamily homologous superfamily	10 — Endochitinase-like

结构域编号 domain_id	2uvoA03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	60 — Wheat Germ Agglutinin (Isolectin 2); domain 1
同源超家族 H-superfamily homologous superfamily	10 — Endochitinase-like

结构域编号 domain_id	2uvoA04
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	60 — Wheat Germ Agglutinin (Isolectin 2); domain 1
同源超家族 H-superfamily homologous superfamily	10 — Endochitinase-like

结构域编号 domain_id	2uvoB01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	60 — Wheat Germ Agglutinin (Isolectin 2); domain 1
同源超家族 H-superfamily homologous superfamily	10 — Endochitinase-like

结构域编号 domain_id	2uvoB02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	60 — Wheat Germ Agglutinin (Isolectin 2); domain 1
同源超家族 H-superfamily homologous superfamily	10 — Endochitinase-like

结构域编号 domain_id	2uvoB03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	60 — Wheat Germ Agglutinin (Isolectin 2); domain 1
同源超家族 H-superfamily homologous superfamily	10 — Endochitinase-like

结构域编号 domain_id	2uvoB04
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	60 — Wheat Germ Agglutinin (Isolectin 2); domain 1
同源超家族 H-superfamily homologous superfamily	10 — Endochitinase-like

结构域编号 domain_id	2uvoE01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	60 — Wheat Germ Agglutinin (Isolectin 2); domain 1
同源超家族 H-superfamily homologous superfamily	10 — Endochitinase-like

结构域编号 domain_id	2uvoE02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	60 — Wheat Germ Agglutinin (Isolectin 2); domain 1
同源超家族 H-superfamily homologous superfamily	10 — Endochitinase-like

结构域编号 domain_id	2uvoE03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	60 — Wheat Germ Agglutinin (Isolectin 2); domain 1
同源超家族 H-superfamily homologous superfamily	10 — Endochitinase-like

结构域编号 domain_id	2uvoE04
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	60 — Wheat Germ Agglutinin (Isolectin 2); domain 1
同源超家族 H-superfamily homologous superfamily	10 — Endochitinase-like

结构域编号 domain_id	2uvoF01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	60 — Wheat Germ Agglutinin (Isolectin 2); domain 1
同源超家族 H-superfamily homologous superfamily	10 — Endochitinase-like

结构域编号 domain_id	2uvoF02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	60 — Wheat Germ Agglutinin (Isolectin 2); domain 1
同源超家族 H-superfamily homologous superfamily	10 — Endochitinase-like

结构域编号 domain_id	2uvoF03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	60 — Wheat Germ Agglutinin (Isolectin 2); domain 1
同源超家族 H-superfamily homologous superfamily	10 — Endochitinase-like

结构域编号 domain_id	2uvoF04
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	60 — Wheat Germ Agglutinin (Isolectin 2); domain 1
同源超家族 H-superfamily homologous superfamily	10 — Endochitinase-like

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晶胞边长 a length_a	44.390 Å
晶胞边长 b length_b	91.510 Å
晶胞边长 c length_c	94.500 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	82.00 °
晶胞夹角 γ angle_gamma	90.00 °
晶胞分子数 Z z_pdb	8

空间群 space_group	P 1 21 1
空间群编号 int_tables_number	4
晶系 crystal_system	—

分辨率 resolution	1.400 Å
最低分辨率 resolution_low	93.660 Å
R 因子 r_factor	0.1820
R_work r_work	0.1810
R_free r_free	0.2040

High Resolution Crystal Structure of Wheat Germ Agglutinin in Complex with N-Acetyl-D-Glucosamine

1. 蛋白身份与相关结构 Protein Identity & Related Structures

AGGLUTININ ISOLECTIN 1

当前结构中的状态

数据库中的同蛋白其他状态

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

2uvo__assembly_1__model_1

2uvo__assembly_1__model_1 | I(q)

2uvo__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (5)

实体 1 Entity 1 polymer

聚合物 Polymer

实体 2 Entity 2 non-polymer

实体 3 Entity 3 non-polymer

实体 4 Entity 4 non-polymer

实体 5 Entity 5 water

6. 折叠分类 (SCOP + CATH) 32 domains

SCOP 2.08 (16 domains)

CATH v4.4 (16 domains)

7. 引用文献 (1)

High Resolution Crystal Structure of Wheat Germ Agglutinin in Complex with N-Acetyl-D-Glucosamine

1. 蛋白身份与相关结构 Protein Identity & Related Structures

AGGLUTININ ISOLECTIN 1

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

2uvo__assembly_1__model_1

2uvo__assembly_1__model_1 | I(q)

2uvo__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (5)

实体 1 Entity 1 polymer

聚合物 Polymer

实体 2 Entity 2 non-polymer

实体 3 Entity 3 non-polymer

实体 4 Entity 4 non-polymer

实体 5 Entity 5 water

6. 折叠分类 (SCOP + CATH) 32 domains

SCOP 2.08 (16 domains)

CATH v4.4 (16 domains)

7. 引用文献 (1)