2wb1
The complete structure of the archaeal 13-subunit DNA-directed RNA Polymerase
1. 蛋白身份与相关结构 Protein Identity & Related Structures
当前条目没有可用的 UniProt 蛋白身份。
七张关系表仍保留该条目的 assembly 与组成信息，但缺少统一蛋白身份时，不能可靠建立跨 PDB 的同蛋白链接。
当前条目的 assembly 组成
| Assembly | 物理组成 | 蛋白状态 | 蛋白 / DNA / RNA / 其他聚合物 | 数据核对 |
|---|---|---|---|---|
| 1 | 蛋白异源复合物 | 异源复合物 | 13 / 0 / 0 / 0 | 与蛋白数一致 |
| 2 | 蛋白异源复合物 | 异源复合物 | 13 / 0 / 0 / 0 | 与蛋白数一致 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
2. 结构基本信息 2. Structure Basics
| 条目编号 entry_id | 2wb1 |
| 沉积日期 deposition_date | 2009-02-19 |
| 结构标题 title | The complete structure of the archaeal 13-subunit DNA-directed RNA Polymerase |
| 关键词 keywords | RNA-POLYMERASE, MULTI-SUBUNIT ENZYME, TRANSCRIPTION; TRANSCRIPTION |
| 实验方法 method | X-RAY DIFFRACTION |
3. Official assembly/model 理论 SAXS Official SAXS Profiles
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
2wb1__assembly_1__model_1
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
2wb1__assembly_1__model_1 | I(q)
2wb1__assembly_1__model_1 | P(r) · Pending
| Rg（Guinier） | 48.84 Å |
| Rg（电子密度） | 48.45 Å |
| 总 Rg | 48.83 Å |
| 原子数 | 26356 |
| 残基数 | 3324 |
| 排除体积 | 473670 ų |
| 最大 q | 0.500 Å⁻¹ |
4. 晶体学与实验 4. Crystallography & Experiment
5. 实体与聚合物信息 Entities & Polymers (16)
6. 折叠分类 (SCOP + CATH) 54 domains
CATH v4.4 (54 domains)
| 结构域编号 domain_id | 2wb1A02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 40 — Barwin-like endoglucanases |
| 同源超家族 H-superfamily homologous superfamily | 20 — |
| 结构域编号 domain_id | 2wb1A03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 1490 — Dna Ligase; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 180 — RNA polymerase ii |
| 结构域编号 domain_id | 2wb1A04 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 10 — Arc Repressor Mutant, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 1950 — |
| 结构域编号 domain_id | 2wb1A05 |
| 类 Class class | 4 — Few Secondary Structures |
| 架构 Architecture architecture | 10 — Irregular |
| 拓扑 Topology topology | 320 — Dihydrolipoamide Transferase |
| 同源超家族 H-superfamily homologous superfamily | 40 — |
| 结构域编号 domain_id | 2wb1A06 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 60 — Sandwich |
| 拓扑 Topology topology | 40 — Immunoglobulin-like |
| 同源超家族 H-superfamily homologous superfamily | 2940 — |
| 结构域编号 domain_id | 2wb1A07 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 132 — Topoisomerase I; Chain A, domain 4 |
| 同源超家族 H-superfamily homologous superfamily | 30 — RNA polymerase Rpb1 funnel domain |
| 结构域编号 domain_id | 2wb1A08 |
| 类 Class class | 6 — Special |
| 架构 Architecture architecture | 10 — Helix non-globular |
| 拓扑 Topology topology | 250 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces |
| 同源超家族 H-superfamily homologous superfamily | 2940 — |
| 结构域编号 domain_id | 2wb1A09 |
| 类 Class class | 6 — Special |
| 架构 Architecture architecture | 20 — Other non-globular |
| 拓扑 Topology topology | 50 — N-terminal domain of TfIIb |
| 同源超家族 H-superfamily homologous superfamily | 80 — |
| 结构域编号 domain_id | 2wb1B04 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 1110 — Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 |
| 同源超家族 H-superfamily homologous superfamily | 10 — RNA polymerase Rpb2, domain 2 |
| 结构域编号 domain_id | 2wb1B05 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 1070 — Hypothetical Protein Ta0175; Chain: A, domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 20 — |
| 结构域编号 domain_id | 2wb1B06 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 270 — Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 |
| 同源超家族 H-superfamily homologous superfamily | 10 — DNA-directed RNA polymerase, subunit 2, domain 6 |
| 结构域编号 domain_id | 2wb1B07 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P) |
| 同源超家族 H-superfamily homologous superfamily | 150 — RNA polymerase II, Rpb2 subunit, wall domain |
| 结构域编号 domain_id | 2wb1B08 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 1800 — DCoH-like |
| 同源超家族 H-superfamily homologous superfamily | 10 — RNA polymerase alpha subunit dimerisation domain |
| 结构域编号 domain_id | 2wb1C02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 150 — DNA polymerase; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 390 — |
| 结构域编号 domain_id | 2wb1D01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 1360 — Gyrase A; domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 10 — RNA polymerase, RBP11-like subunit |
| 结构域编号 domain_id | 2wb1D02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 170 — Beta Complex |
| 拓扑 Topology topology | 120 — RNA Polymerase Alpha Subunit; Chain A, domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 12 — DNA-directed RNA polymerase, insert domain |
| 结构域编号 domain_id | 2wb1D03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 70 — Alpha-Beta Plaits |
| 同源超家族 H-superfamily homologous superfamily | 20 — |
| 结构域编号 domain_id | 2wb1E01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 1490 — Dna Ligase; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 120 — RNA polymerase Rpb7-like, N-terminal domain |
| 结构域编号 domain_id | 2wb1E02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P) |
| 同源超家族 H-superfamily homologous superfamily | 140 — Nucleic acid-binding proteins |
| 结构域编号 domain_id | 2wb1F01 |
| 类 Class class | 6 — Special |
| 架构 Architecture architecture | 10 — Helix non-globular |
| 拓扑 Topology topology | 140 — Helix Hairpins |
| 同源超家族 H-superfamily homologous superfamily | 930 — |
| 结构域编号 domain_id | 2wb1F02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 150 — DNA polymerase; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 80 — HRDC domain |
| 结构域编号 domain_id | 2wb1G00 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P) |
| 同源超家族 H-superfamily homologous superfamily | 140 — Nucleic acid-binding proteins |
| 结构域编号 domain_id | 2wb1H00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 940 — Eukaryotic RPB6 RNA polymerase subunit |
| 同源超家族 H-superfamily homologous superfamily | 20 — RPB5-like RNA polymerase subunit |
| 结构域编号 domain_id | 2wb1I00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 940 — Eukaryotic RPB6 RNA polymerase subunit |
| 同源超家族 H-superfamily homologous superfamily | 10 — RNA polymerase subunit, RPB6/omega |
| 结构域编号 domain_id | 2wb1K00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 940 — Eukaryotic RPB6 RNA polymerase subunit |
| 同源超家族 H-superfamily homologous superfamily | 10 — RNA polymerase subunit, RPB6/omega |
| 结构域编号 domain_id | 2wb1L00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 1360 — Gyrase A; domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 10 — RNA polymerase, RBP11-like subunit |
| 结构域编号 domain_id | 2wb1M00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 1360 — Gyrase A; domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 10 — RNA polymerase, RBP11-like subunit |
| 结构域编号 domain_id | 2wb1N00 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 10 — Arc Repressor Mutant, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 60 — Homeodomain-like |
| 结构域编号 domain_id | 2wb1O00 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 10 — Arc Repressor Mutant, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 60 — Homeodomain-like |
| 结构域编号 domain_id | 2wb1P00 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 20 — Single Sheet |
| 拓扑 Topology topology | 28 — Rubrerythrin, domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 30 — RNA polymerase ii, chain L |
| 结构域编号 domain_id | 2wb1R04 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 1110 — Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 |
| 同源超家族 H-superfamily homologous superfamily | 10 — RNA polymerase Rpb2, domain 2 |
| 结构域编号 domain_id | 2wb1R05 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 1070 — Hypothetical Protein Ta0175; Chain: A, domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 20 — |
| 结构域编号 domain_id | 2wb1R06 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 270 — Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 |
| 同源超家族 H-superfamily homologous superfamily | 10 — DNA-directed RNA polymerase, subunit 2, domain 6 |
| 结构域编号 domain_id | 2wb1R07 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P) |
| 同源超家族 H-superfamily homologous superfamily | 150 — RNA polymerase II, Rpb2 subunit, wall domain |
| 结构域编号 domain_id | 2wb1R08 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 1800 — DCoH-like |
| 同源超家族 H-superfamily homologous superfamily | 10 — RNA polymerase alpha subunit dimerisation domain |
| 结构域编号 domain_id | 2wb1S01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 1360 — Gyrase A; domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 10 — RNA polymerase, RBP11-like subunit |
| 结构域编号 domain_id | 2wb1S02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 170 — Beta Complex |
| 拓扑 Topology topology | 120 — RNA Polymerase Alpha Subunit; Chain A, domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 12 — DNA-directed RNA polymerase, insert domain |
| 结构域编号 domain_id | 2wb1S03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 70 — Alpha-Beta Plaits |
| 同源超家族 H-superfamily homologous superfamily | 20 — |
| 结构域编号 domain_id | 2wb1T01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 1490 — Dna Ligase; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 120 — RNA polymerase Rpb7-like, N-terminal domain |
| 结构域编号 domain_id | 2wb1T02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P) |
| 同源超家族 H-superfamily homologous superfamily | 140 — Nucleic acid-binding proteins |
| 结构域编号 domain_id | 2wb1U01 |
| 类 Class class | 6 — Special |
| 架构 Architecture architecture | 10 — Helix non-globular |
| 拓扑 Topology topology | 140 — Helix Hairpins |
| 同源超家族 H-superfamily homologous superfamily | 930 — |
| 结构域编号 domain_id | 2wb1U02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 150 — DNA polymerase; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 80 — HRDC domain |
| 结构域编号 domain_id | 2wb1V00 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P) |
| 同源超家族 H-superfamily homologous superfamily | 140 — Nucleic acid-binding proteins |
| 结构域编号 domain_id | 2wb1W02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 40 — Barwin-like endoglucanases |
| 同源超家族 H-superfamily homologous superfamily | 20 — |
| 结构域编号 domain_id | 2wb1W03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 1490 — Dna Ligase; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 180 — RNA polymerase ii |
| 结构域编号 domain_id | 2wb1W04 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 10 — Arc Repressor Mutant, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 1950 — |
| 结构域编号 domain_id | 2wb1W05 |
| 类 Class class | 4 — Few Secondary Structures |
| 架构 Architecture architecture | 10 — Irregular |
| 拓扑 Topology topology | 320 — Dihydrolipoamide Transferase |
| 同源超家族 H-superfamily homologous superfamily | 40 — |
| 结构域编号 domain_id | 2wb1W06 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 60 — Sandwich |
| 拓扑 Topology topology | 40 — Immunoglobulin-like |
| 同源超家族 H-superfamily homologous superfamily | 2940 — |
| 结构域编号 domain_id | 2wb1W07 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 132 — Topoisomerase I; Chain A, domain 4 |
| 同源超家族 H-superfamily homologous superfamily | 30 — RNA polymerase Rpb1 funnel domain |
| 结构域编号 domain_id | 2wb1W08 |
| 类 Class class | 6 — Special |
| 架构 Architecture architecture | 10 — Helix non-globular |
| 拓扑 Topology topology | 250 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces |
| 同源超家族 H-superfamily homologous superfamily | 2940 — |
| 结构域编号 domain_id | 2wb1W09 |
| 类 Class class | 6 — Special |
| 架构 Architecture architecture | 20 — Other non-globular |
| 拓扑 Topology topology | 50 — N-terminal domain of TfIIb |
| 同源超家族 H-superfamily homologous superfamily | 80 — |
| 结构域编号 domain_id | 2wb1X00 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 20 — Single Sheet |
| 拓扑 Topology topology | 28 — Rubrerythrin, domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 30 — RNA polymerase ii, chain L |
| 结构域编号 domain_id | 2wb1Y02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 150 — DNA polymerase; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 390 — |
| 结构域编号 domain_id | 2wb1Z00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 940 — Eukaryotic RPB6 RNA polymerase subunit |
| 同源超家族 H-superfamily homologous superfamily | 20 — RPB5-like RNA polymerase subunit |