HOMO SAPIENS
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein monomer | Monomer | Protein 1 | THIOCYANATE ION × 2 1,2-ETHANEDIOL × 3 water × 1 | Consistent with protein count |
| UniProt name | MEFV_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–191； UniProt 586–776 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 2wl1 |
| Deposition date deposition_date | 2009-06-19 |
| Structure title title | Pyrin PrySpry domain |
| Keywords keywords | ;AMYLOIDOSIS, POLYMORPHISM, CYTOSKELETON, ACTIN-BINDING INFLAMMATORY RESPONSE, METAL-BINDING, SIGNALING PROTEIN, DISEASE MUTATION, PRYSPRY ;; SIGNALING PROTEIN |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 17.18 Å |
| Rg (electron density) | 15.70 Å |
| Total Rg | 16.89 Å |
| Atom count | 1500 |
| Residues | 191 |
| Excluded volume | 26810 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d2wl1a_ |
| Class class | b — All beta proteins |
| Fold Fold fold | b.29 — Concanavalin A-like lectins/glucanases |
| Superfamily Superfamily superfamily | b.29.1 — Concanavalin A-like lectins/glucanases |
| Family Family family | b.29.1.0 — automated matches |
| Domain ID domain_id | 2wl1A00 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 60 — Sandwich |
| Topology topology | 120 — Jelly Rolls |
| Homologous superfamily homologous superfamily | 920 — SPRY domain |