2wzs

Structure of the Family GH92 Inverting Mannosidase BT3990 from Bacteroides thetaiotaomicron VPI-5482 in complex with Mannoimidazole

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

PUTATIVE ALPHA-1,2-MANNOSIDASE

BACTEROIDES THETAIOTAOMICRON

UniProt Q8A0N1

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白单体 单体 蛋白 1 CALCIUM ION × 1 (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL × 1 GLYCEROL × 3 water × 1 与蛋白数一致
2 蛋白单体 单体 蛋白 1 CALCIUM ION × 1 (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL × 1 GLYCEROL × 4 water × 1 与蛋白数一致
3 蛋白单体 单体 蛋白 1 CALCIUM ION × 1 (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL × 1 GLYCEROL × 4 water × 1 与蛋白数一致
4 蛋白单体 单体 蛋白 1 CALCIUM ION × 1 (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL × 1 GLYCEROL × 4 water × 1 与蛋白数一致
5 蛋白单体 单体 蛋白 1 CALCIUM ION × 1 (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL × 1 GLYCEROL × 3 water × 1 与蛋白数一致
6 蛋白单体 单体 蛋白 1 CALCIUM ION × 1 (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL × 1 GLYCEROL × 1 water × 1 与蛋白数一致
7 蛋白单体 单体 蛋白 1 CALCIUM ION × 1 (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL × 1 water × 1 与蛋白数一致
8 蛋白单体 单体 蛋白 1 CALCIUM ION × 1 (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL × 1 water × 1 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 Q8A0N1_BACTN
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 1–736; UniProt 20–755 作者链 B; PDB构建体 1–736; UniProt 20–755 作者链 C; PDB构建体 1–736; UniProt 20–755 作者链 D; PDB构建体 1–736; UniProt 20–755 作者链 E; PDB构建体 1–736; UniProt 20–755 作者链 F; PDB构建体 1–736; UniProt 20–755 作者链 G; PDB构建体 1–736; UniProt 20–755 作者链 H; PDB构建体 1–736; UniProt 20–755

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id2wzs
沉积日期 deposition_date2009-12-02
结构标题 titleStructure of the Family GH92 Inverting Mannosidase BT3990 from Bacteroides thetaiotaomicron VPI-5482 in complex with Mannoimidazole
关键词 keywordsGLYCOSIDE HYDROLASE FAMILY 92, ALPHA-1\, 2 LINKAGE, BT3990, HYDROLASE; HYDROLASE
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

2wzs__assembly_8__model_1

Assembly 8 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

2wzs__assembly_8__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

2wzs__assembly_8__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)27.26 Å
Rg(电子密度)26.46 Å
总 Rg27.33 Å
原子数5976
残基数736
排除体积105530 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 2wzs__assembly_1__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
2 1 2wzs__assembly_2__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
3 1 2wzs__assembly_3__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
4 1 2wzs__assembly_4__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
5 1 2wzs__assembly_5__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
6 1 2wzs__assembly_6__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
7 1 2wzs__assembly_7__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
8 1 2wzs__assembly_8__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (5)

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6. 折叠分类 (SCOP + CATH) 32 domains

CATH v4.4 (32 domains)

结构域编号 domain_id2wzsA01
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology98 — Beta-galactosidase; Chain A, domain 5
同源超家族 H-superfamily homologous superfamily10 —
结构域编号 domain_id2wzsA02
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology2080 — GH92 mannosidase fold
同源超家族 H-superfamily homologous superfamily10 — GH92 mannosidase domain
结构域编号 domain_id2wzsA03
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily60 — alpha-1,2-mannosidase
结构域编号 domain_id2wzsA04
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1610 — Glycosyl hydrolase family fold
同源超家族 H-superfamily homologous superfamily10 — alpha-1,2-mannosidases domains
结构域编号 domain_id2wzsB01
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology98 — Beta-galactosidase; Chain A, domain 5
同源超家族 H-superfamily homologous superfamily10 —
结构域编号 domain_id2wzsB02
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology2080 — GH92 mannosidase fold
同源超家族 H-superfamily homologous superfamily10 — GH92 mannosidase domain
结构域编号 domain_id2wzsB03
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily60 — alpha-1,2-mannosidase
结构域编号 domain_id2wzsB04
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1610 — Glycosyl hydrolase family fold
同源超家族 H-superfamily homologous superfamily10 — alpha-1,2-mannosidases domains
结构域编号 domain_id2wzsC01
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology98 — Beta-galactosidase; Chain A, domain 5
同源超家族 H-superfamily homologous superfamily10 —
结构域编号 domain_id2wzsC02
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology2080 — GH92 mannosidase fold
同源超家族 H-superfamily homologous superfamily10 — GH92 mannosidase domain
结构域编号 domain_id2wzsC03
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily60 — alpha-1,2-mannosidase
结构域编号 domain_id2wzsC04
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1610 — Glycosyl hydrolase family fold
同源超家族 H-superfamily homologous superfamily10 — alpha-1,2-mannosidases domains
结构域编号 domain_id2wzsD01
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology98 — Beta-galactosidase; Chain A, domain 5
同源超家族 H-superfamily homologous superfamily10 —
结构域编号 domain_id2wzsD02
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology2080 — GH92 mannosidase fold
同源超家族 H-superfamily homologous superfamily10 — GH92 mannosidase domain
结构域编号 domain_id2wzsD03
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily60 — alpha-1,2-mannosidase
结构域编号 domain_id2wzsD04
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1610 — Glycosyl hydrolase family fold
同源超家族 H-superfamily homologous superfamily10 — alpha-1,2-mannosidases domains
结构域编号 domain_id2wzsE01
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology98 — Beta-galactosidase; Chain A, domain 5
同源超家族 H-superfamily homologous superfamily10 —
结构域编号 domain_id2wzsE02
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology2080 — GH92 mannosidase fold
同源超家族 H-superfamily homologous superfamily10 — GH92 mannosidase domain
结构域编号 domain_id2wzsE03
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily60 — alpha-1,2-mannosidase
结构域编号 domain_id2wzsE04
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1610 — Glycosyl hydrolase family fold
同源超家族 H-superfamily homologous superfamily10 — alpha-1,2-mannosidases domains
结构域编号 domain_id2wzsF01
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology98 — Beta-galactosidase; Chain A, domain 5
同源超家族 H-superfamily homologous superfamily10 —
结构域编号 domain_id2wzsF02
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology2080 — GH92 mannosidase fold
同源超家族 H-superfamily homologous superfamily10 — GH92 mannosidase domain
结构域编号 domain_id2wzsF03
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily60 — alpha-1,2-mannosidase
结构域编号 domain_id2wzsF04
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1610 — Glycosyl hydrolase family fold
同源超家族 H-superfamily homologous superfamily10 — alpha-1,2-mannosidases domains
结构域编号 domain_id2wzsG01
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology98 — Beta-galactosidase; Chain A, domain 5
同源超家族 H-superfamily homologous superfamily10 —
结构域编号 domain_id2wzsG02
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology2080 — GH92 mannosidase fold
同源超家族 H-superfamily homologous superfamily10 — GH92 mannosidase domain
结构域编号 domain_id2wzsG03
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily60 — alpha-1,2-mannosidase
结构域编号 domain_id2wzsG04
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1610 — Glycosyl hydrolase family fold
同源超家族 H-superfamily homologous superfamily10 — alpha-1,2-mannosidases domains
结构域编号 domain_id2wzsH01
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology98 — Beta-galactosidase; Chain A, domain 5
同源超家族 H-superfamily homologous superfamily10 —
结构域编号 domain_id2wzsH02
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology2080 — GH92 mannosidase fold
同源超家族 H-superfamily homologous superfamily10 — GH92 mannosidase domain
结构域编号 domain_id2wzsH03
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily60 — alpha-1,2-mannosidase
结构域编号 domain_id2wzsH04
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1610 — Glycosyl hydrolase family fold
同源超家族 H-superfamily homologous superfamily10 — alpha-1,2-mannosidases domains
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7. 引用文献 (1)