SAXSdb — 2xad

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1. Protein Identity and Related Structures Protein Identity & Related Structures

N-ACYL GLM PEUDO-TEICOPLANIN DEACETYLASE

ACTINOPLANES TEICHOMYCETICUS

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 2	TEICOPLANIN × 1 beta-D-mannopyranose × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 2-amino-2-deoxy-beta-D-glucopyranose × 1 8-METHYLNONANOIC ACID × 1 water × 2	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 2	TEICOPLANIN × 1 beta-D-mannopyranose × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 2-amino-2-deoxy-beta-D-glucopyranose × 1 8-METHYLNONANOIC ACID × 1 water × 2	Consistent with protein count
3	Protein heterocomplex	Heteromer	Protein 2	TEICOPLANIN × 1 beta-D-mannopyranose × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 2-amino-2-deoxy-beta-D-glucopyranose × 1 8-METHYLNONANOIC ACID × 1 water × 2	Consistent with protein count
4	Protein heterocomplex	Heteromer	Protein 2	TEICOPLANIN × 1 beta-D-mannopyranose × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 2-amino-2-deoxy-beta-D-glucopyranose × 1 8-METHYLNONANOIC ACID × 1 water × 2	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q6ZZJ1_ACTTI
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–273； UniProt 1–273 Author chain B； PDBConstruct 1–273； UniProt 1–273 Author chain C； PDBConstruct 1–273； UniProt 1–273 Author chain D； PDBConstruct 1–273； UniProt 1–273

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	2xad
Deposition date deposition_date	2010-03-31
Structure title title	Crystal structure of deacetylase-teicoplanin complex in biosynthesis pathway of teicoplanin
Keywords keywords	OXIDOREDUCTASE-ANTIBIOTIC COMPLEX, ANTIBIOTIC, A40926, GLYCOPEPTIDE; OXIDOREDUCTASE/ANTIBIOTIC
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2xad__assembly_2__model_1

Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2xad__assembly_2__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

2xad__assembly_2__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	19.12 Å
Rg (electron density)	17.70 Å
Total Rg	18.64 Å
Atom count	2138
Residues	255
Excluded volume	37509 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`2xad__assembly_1__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`2xad__assembly_2__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	1	`2xad__assembly_3__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	1	`2xad__assembly_4__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (7)

Entity 1 Entity 1 polymer

Description description	N-ACYL GLM PEUDO-TEICOPLANIN DEACETYLASE
Molecular weight formula_weight	30271.0 kDa
Mutation mutation	YES
Source method src_method	man
Copy count entity_count	4

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D
Atom count atom_count	9379

MPHDPGATRLLAISPHLDDAVLSFGAGLAQAAQDGANVLVYTVFAGAAQPPYSPAAQRMHTIWGLAPDDDAVLYRRKEDIAALDHLRVAHRHGRFLDSIYRKLPDGRWLTAHVEGRQKLAVNDHSPDSDHDLVGEVADDIRSIIDEFDPTLVVTCAAIGEHPDNEATRDAALFATHEKNVPVRLWEDLPYAVFKSGAVELPQGFRLGSADVSSVKPEMRSQKFQAVERYSSQMVLLNGSENNLFDRLDEHARQNAPHGGYGETTWPVVRSDDS

Source Source

Source organism organism	ACTINOPLANES TEICHOMYCETICUS
NCBI taxonomy ID ncbi_taxonomy_id	1867
Host organism host_organism	ESCHERICHIA COLI

Entity 2 Entity 2 polymer

Description description	TEICOPLANIN
Molecular weight formula_weight	1207.0 kDa
Source method src_method	nat
Copy count entity_count	4

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	E,F,G,H

GYXGGYX

Entity 3 Entity 3 non-polymer

Description description	beta-D-mannopyranose
Molecular weight formula_weight	180.2 kDa
Source method src_method	man
Copy count entity_count	4

Entity 4 Entity 4 non-polymer

Description description	2-acetamido-2-deoxy-beta-D-glucopyranose
Molecular weight formula_weight	221.2 kDa
Source method src_method	man
Copy count entity_count	4

Entity 5 Entity 5 non-polymer

Description description	2-amino-2-deoxy-beta-D-glucopyranose
Molecular weight formula_weight	179.2 kDa
Source method src_method	man
Copy count entity_count	4

Entity 6 Entity 6 non-polymer

Description description	8-METHYLNONANOIC ACID
Molecular weight formula_weight	172.3 kDa
Source method src_method	syn
Copy count entity_count	4

Entity 7 Entity 7 water

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	814

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6. Fold Classification (SCOP + CATH) 4 domains

CATH v4.4 (4 domains)

Domain ID domain_id	2xadA00
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	10320 — LmbE-like

Domain ID domain_id	2xadB00
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	10320 — LmbE-like

Domain ID domain_id	2xadC00
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	10320 — LmbE-like

Domain ID domain_id	2xadD00
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	10320 — LmbE-like

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Unit-cell length a length_a	58.775 Å
Unit-cell length b length_b	70.713 Å
Unit-cell length c length_c	76.313 Å
Unit-cell angle α angle_alpha	113.89 °
Unit-cell angle β angle_beta	108.29 °
Unit-cell angle γ angle_gamma	98.20 °
Molecules per unit cell Z z_pdb	4

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	—

Resolution resolution	1.700 Å
Low-resolution limit resolution_low	20.000 Å
R factor r_factor	0.2026
R_work r_work	0.2008
R_free r_free	0.2368

Crystal structure of deacetylase-teicoplanin complex in biosynthesis pathway of teicoplanin

1. Protein Identity and Related Structures Protein Identity & Related Structures

N-ACYL GLM PEUDO-TEICOPLANIN DEACETYLASE

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2xad__assembly_2__model_1

2xad__assembly_2__model_1 | I(q)

2xad__assembly_2__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (7)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer

Polymer Polymer

Entity 3 Entity 3 non-polymer

Entity 4 Entity 4 non-polymer

Entity 5 Entity 5 non-polymer

Entity 6 Entity 6 non-polymer

Entity 7 Entity 7 water

6. Fold Classification (SCOP + CATH) 4 domains

CATH v4.4 (4 domains)

7. Citations (1)

Crystal structure of deacetylase-teicoplanin complex in biosynthesis pathway of teicoplanin

1. Protein Identity and Related Structures Protein Identity & Related Structures

N-ACYL GLM PEUDO-TEICOPLANIN DEACETYLASE

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2xad__assembly_2__model_1

2xad__assembly_2__model_1 | I(q)

2xad__assembly_2__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (7)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer

Polymer Polymer

Entity 3 Entity 3 non-polymer

Entity 4 Entity 4 non-polymer

Entity 5 Entity 5 non-polymer

Entity 6 Entity 6 non-polymer

Entity 7 Entity 7 water

6. Fold Classification (SCOP + CATH) 4 domains

CATH v4.4 (4 domains)

7. Citations (1)