SAXSdb — 2yq0

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1. 蛋白身份与相关结构 Protein Identity & Related Structures

ORF 73

HUMAN HERPESVIRUS 8 TYPE M

当前结构中的状态

Assembly	聚集状态	构建体	突变与修饰	配体、离子与共同组分	实验方法与环境	结构质量
1	蛋白同源多聚体同源多聚体蛋白 × 8 PDB 声明：octameric（8）与蛋白拷贝数一致	链 A； UniProt 996–1153	片段：C-TERMINAL DOMAIN, RESIDUES 996-1153	SO4 SULFATE ION × 8	X-RAY DIFFRACTION X-ray结晶条件：VAPOR DIFFUSION, HANGING DROP；pH 2.5；277 K；1 UL OF 1 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 2 MM DTT WAS ADDED TO 1 UL OF 0.1 M SODIUM CITRATE, PH 2.5, 1.5 M AMMONIUM SULFATE. THE MIXTURE WAS INCUBATED AT 4 DEGREE CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.1 M SODIUM CITRATE, PH 2.5, 1.5 M AMMONIUM SULFATE, 25% (V/V) GLYCEROL.	分辨率 3.91 Å R-free 0.317

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly， “相对当前条目”直接指出证据层面的不同；没有差异标签表示当前已读取字段一致。

其他 PDB	相对当前条目 2YQ0	Assembly / 聚集状态	构建体	突变与修饰	配体、离子与非聚合物	实验方法与环境	结构质量
2YPY KSHV LANA (ORF73) C-terminal domain, decameric ring: monoclinic crystal form 提交 2012-11-02	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 G 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149 链 H 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149	未记录	CL CHLORIDE ION × 3	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 9；285 K；1.5 UL OF 2.0 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 10 MM DTT WERE ADDED TO 1.5 UL OF 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000. THE MIXTURE WAS INCUBATED AT 12 DEGREES CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000, 25 % (V/V) GLYCEROL.	分辨率 2.45 Å R-free 0.252
2YPY KSHV LANA (ORF73) C-terminal domain, decameric ring: monoclinic crystal form 提交 2012-11-02	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 C 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149 链 D 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149	未记录	CL CHLORIDE ION × 6	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 9；285 K；1.5 UL OF 2.0 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 10 MM DTT WERE ADDED TO 1.5 UL OF 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000. THE MIXTURE WAS INCUBATED AT 12 DEGREES CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000, 25 % (V/V) GLYCEROL.	分辨率 2.45 Å R-free 0.252
2YPY KSHV LANA (ORF73) C-terminal domain, decameric ring: monoclinic crystal form 提交 2012-11-02	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 3 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 A 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149 链 B 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149	未记录	CL CHLORIDE ION × 6	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 9；285 K；1.5 UL OF 2.0 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 10 MM DTT WERE ADDED TO 1.5 UL OF 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000. THE MIXTURE WAS INCUBATED AT 12 DEGREES CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000, 25 % (V/V) GLYCEROL.	分辨率 2.45 Å R-free 0.252
2YPY KSHV LANA (ORF73) C-terminal domain, decameric ring: monoclinic crystal form 提交 2012-11-02	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 4 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 E 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149 链 F 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149	未记录	CL CHLORIDE ION × 5	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 9；285 K；1.5 UL OF 2.0 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 10 MM DTT WERE ADDED TO 1.5 UL OF 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000. THE MIXTURE WAS INCUBATED AT 12 DEGREES CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000, 25 % (V/V) GLYCEROL.	分辨率 2.45 Å R-free 0.252
2YPY KSHV LANA (ORF73) C-terminal domain, decameric ring: monoclinic crystal form 提交 2012-11-02	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 5 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 I 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149 链 J 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149	未记录	CL CHLORIDE ION × 4	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 9；285 K；1.5 UL OF 2.0 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 10 MM DTT WERE ADDED TO 1.5 UL OF 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000. THE MIXTURE WAS INCUBATED AT 12 DEGREES CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.1 M SODIUM BICINE, PH 9.0, 1.0 M LITHIUM CHLORIDE, 7 % (W/V) PEG 6000, 25 % (V/V) GLYCEROL.	分辨率 2.45 Å R-free 0.252
2YPZ KSHV LANA (ORF73) C-terminal domain, decameric ring: orthorhombic crystal form 提交 2012-11-02	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 I 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149 链 J 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149	未记录	未记录非水小分子	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；1.5 UL OF 0.8 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 200 MM LICL, 4 MM DTT WERE ADDED TO 1.5 UL OF 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350. THE MIXTURE WAS INCUBATED AT 20 DEGREE CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350, 30 % (V/V) GLYCEROL.	分辨率 3.20 Å R-free 0.265
2YPZ KSHV LANA (ORF73) C-terminal domain, decameric ring: orthorhombic crystal form 提交 2012-11-02	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 C 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149 链 D 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149	未记录	未记录非水小分子	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；1.5 UL OF 0.8 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 200 MM LICL, 4 MM DTT WERE ADDED TO 1.5 UL OF 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350. THE MIXTURE WAS INCUBATED AT 20 DEGREE CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350, 30 % (V/V) GLYCEROL.	分辨率 3.20 Å R-free 0.265
2YPZ KSHV LANA (ORF73) C-terminal domain, decameric ring: orthorhombic crystal form 提交 2012-11-02	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 3 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 A 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149 链 B 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149	未记录	未记录非水小分子	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；1.5 UL OF 0.8 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 200 MM LICL, 4 MM DTT WERE ADDED TO 1.5 UL OF 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350. THE MIXTURE WAS INCUBATED AT 20 DEGREE CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350, 30 % (V/V) GLYCEROL.	分辨率 3.20 Å R-free 0.265
2YPZ KSHV LANA (ORF73) C-terminal domain, decameric ring: orthorhombic crystal form 提交 2012-11-02	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 4 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 G 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149 链 H 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149	未记录	未记录非水小分子	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；1.5 UL OF 0.8 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 200 MM LICL, 4 MM DTT WERE ADDED TO 1.5 UL OF 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350. THE MIXTURE WAS INCUBATED AT 20 DEGREE CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350, 30 % (V/V) GLYCEROL.	分辨率 3.20 Å R-free 0.265
2YPZ KSHV LANA (ORF73) C-terminal domain, decameric ring: orthorhombic crystal form 提交 2012-11-02	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 5 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 E 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149 链 F 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149	未记录	未记录非水小分子	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7.6；293 K；1.5 UL OF 0.8 MM PROTEIN IN 5 MM BISTRIS, PH 6.5, 200 MM LICL, 4 MM DTT WERE ADDED TO 1.5 UL OF 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350. THE MIXTURE WAS INCUBATED AT 20 DEGREE CENTIGRADE IN A HANGING DROP SETUP. CRYSTALS GREW IN A FEW DAYS AND WERE CRYO-PROTECTED BY SHORT SOAKING IN 0.2 M LITHIUM CITRATE, PH 7.6, 20 % (W/V) PEG 3350, 30 % (V/V) GLYCEROL.	分辨率 3.20 Å R-free 0.265
4UZB KSHV LANA (ORF73) C-terminal domain mutant bound to LBS1 DNA (R1039Q, R1040Q, K1055E, K1109A, D1110A, A1121E, K1138S, K1140D, K1141D) 提交 2014-09-05	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白–DNA 同源多聚体；蛋白 × 2 PDB 声明：tetrameric	链 A 1008–1146（139 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1008-1146 链 B 1008–1146（139 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1008-1146	突变：R1039Q, R1040Q, K1055E, K1109A, D1110A, A1121E, K1138S, K1140D, K1141D 突变：R1039Q, R1040Q, K1055E, K1109A, D1110A, A1121E, K1138S, K1140D, K1141D	未记录非水小分子	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 6.6；297 K；0.9 UL OF 1.60 MM LANA(1008-1146) MUTANT, 0.96 MM DSDNA, 10 MM BISTRIS PH 6.5, 0.9 M NACL, AND 5 MM DTT WERE ADDED TO 0.9 UL OF RESERVOIR SOLUTION CONTAINING 50 MM MES PH 6.6, 27% PEG4000, AND 0.3 M AMMONIUM ACETATE IN A HANGING DROP SETUP. CRYSTALS GREW WITHIN FIVE DAYS AT 24 DEGREES CENTIGRADE.	分辨率 2.87 Å R-free 0.155
4UZC KSHV LANA (ORF73) C-terminal domain, spiral: hexagonal crystal form 提交 2014-09-05	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白同源多聚体同源多聚体；蛋白 × 48 PDB 声明：48-meric	链 A 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149 链 B 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149 链 C 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149 链 D 1013–1149（137 aa）片段：C-TERMINAL DOMAIN, RESIDUES 1013-1149	未记录	未记录非水小分子	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；0.4 UL OF 31.5 MG/ML PROTEIN IN 5 MM BISTRIS-CL, 5 MM DTT, PH 6.5 WERE AS SUCH EQUILIBRATED AGAINST A RESERVOIR SOLUTION OF 170 MM LITHIUM ACETATE AND 18% (W/V) PEG3350 IN A SITTING DROP SETUP AT 20 DEGREE CENTIGRADE. AFTER TWO DAYS, CRYSTALS WERE DETACHED FROM THE CARRIER PLASTIC BY ADDING 1 UL OF 2 M AMMONIUM FORMATE.	分辨率 3.70 Å R-free 0.239
5A76 KSHV LANA (ORF73) C-terminal domain, open non-ring conformation: orthorhombic crystal form 提交 2015-07-02	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 E 1018–1150（133 aa）片段：DNA-BINDING DOMAIN, UNP RESIDUES 1018-1150 链 F 1018–1150（133 aa）片段：DNA-BINDING DOMAIN, UNP RESIDUES 1018-1150	未记录	MG MAGNESIUM ION × 1	X-RAY DIFFRACTION X-ray结晶条件 pH 3；100 MM CITRIC ACID, PH 3.0, 1200 MM MAGNESIUM CHLORIDE.	分辨率 3.80 Å R-free 0.269
5A76 KSHV LANA (ORF73) C-terminal domain, open non-ring conformation: orthorhombic crystal form 提交 2015-07-02	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 C 1018–1150（133 aa）片段：DNA-BINDING DOMAIN, UNP RESIDUES 1018-1150 链 D 1018–1150（133 aa）片段：DNA-BINDING DOMAIN, UNP RESIDUES 1018-1150	未记录	MG MAGNESIUM ION × 1	X-RAY DIFFRACTION X-ray结晶条件 pH 3；100 MM CITRIC ACID, PH 3.0, 1200 MM MAGNESIUM CHLORIDE.	分辨率 3.80 Å R-free 0.269
5A76 KSHV LANA (ORF73) C-terminal domain, open non-ring conformation: orthorhombic crystal form 提交 2015-07-02	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 3 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 A 1018–1150（133 aa）片段：DNA-BINDING DOMAIN, UNP RESIDUES 1018-1150 链 B 1018–1150（133 aa）片段：DNA-BINDING DOMAIN, UNP RESIDUES 1018-1150	未记录	MG MAGNESIUM ION × 1	X-RAY DIFFRACTION X-ray结晶条件 pH 3；100 MM CITRIC ACID, PH 3.0, 1200 MM MAGNESIUM CHLORIDE.	分辨率 3.80 Å R-free 0.269
5A76 KSHV LANA (ORF73) C-terminal domain, open non-ring conformation: orthorhombic crystal form 提交 2015-07-02	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 4 蛋白同源多聚体同源多聚体；蛋白 × 2 PDB 声明：dimeric	链 G 1018–1150（133 aa）片段：DNA-BINDING DOMAIN, UNP RESIDUES 1018-1150 链 H 1018–1150（133 aa）片段：DNA-BINDING DOMAIN, UNP RESIDUES 1018-1150	未记录	MG MAGNESIUM ION × 1	X-RAY DIFFRACTION X-ray结晶条件 pH 3；100 MM CITRIC ACID, PH 3.0, 1200 MM MAGNESIUM CHLORIDE.	分辨率 3.80 Å R-free 0.269
7BCY X-ray structure of WDR5delta24 bound to the Kaposi's sarcoma herpesvirus LANA win motif peptide 提交 2020-12-21	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 2 PDB 声明：dimeric	链 Q 23–32（10 aa）	非标准单体：是（mmCIF未提供具体位点）	未记录非水小分子	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 5.5；294 K；100 mM Bis-Tris pH 5.5, 50 mM (NH4)2SO4, 25% PEG3350	分辨率 1.50 Å R-free 0.227
7BCY X-ray structure of WDR5delta24 bound to the Kaposi's sarcoma herpesvirus LANA win motif peptide 提交 2020-12-21	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白异源复合物异源复合物；蛋白 × 2 PDB 声明：dimeric	链 P 23–32（10 aa）	非标准单体：是（mmCIF未提供具体位点）	未记录非水小分子	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 5.5；294 K；100 mM Bis-Tris pH 5.5, 50 mM (NH4)2SO4, 25% PEG3350	分辨率 1.50 Å R-free 0.227

共 6 个其他 PDB 条目、18 个 assembly。打开独立比较页并筛选聚集状态

查看构建体与数据证据

UniProt名称	Q76SB0_HHV8
Isoform	—
PDB实体	1
链与序列区间	作者链 A； PDB构建体 3–160； UniProt 996–1153

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id	2yq0
沉积日期 deposition_date	2012-11-02
结构标题 title	KSHV LANA (ORF73) C-terminal domain, octameric ring: cubic crystal form
关键词 keywords	;VIRAL PROTEIN, LATENCY-ASSOCIATED NUCLEAR ANTIGEN, LANA-1, DNA-BINDING DOMAIN, ORIGIN-BINDING DOMAIN, OLIGOMERIZATION DOMAIN, KAPOSI'S SARCOMA-ASSOCIATED HERPESVIRUS, GAMMAHERPESVIRUS, RHADINOVIRUS, PRIMARY EFFUSION LYMPHOMA, MULTICENTRIC CASTLEMAN'S DISEASE, TUMOR VIRUS, CANCER, MURID HERPESVIRUS 4, MUHV-4, MURID HERPESVIRUS 68, MHV-68 ;; VIRAL PROTEIN
实验方法 method	X-RAY DIFFRACTION

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3. SAXS 参数 (CRYSOL 理论计算) 3. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier	15.18 Å
回转半径 Rg (电子) rg_electron	14.10 Å
零角强度 I(0) i0	3490320.00
分子量 molecular_weight	13503.0 kDa
排除体积 excluded_volume	17088 Å³
包络体积 envelope_volume	19784 Å³
水化壳体积 shell_volume	11992 Å³
包络直径 envelope_diameter	51.0 Å
壳层 Rg shell_rg	19.77 Å
包络 Rg envelope_rg	14.65 Å
形状 Rg shape_rg	14.05 Å
总 Rg total_rg	15.46 Å
总原子数 total_atoms	951
残基数 n_residues	118
球谐函数阶数 n_harmonics	20
q 范围 q_range	— – 0.5000 Å⁻¹
数据点数 n_points	101
壳层类型 shell_type	directional
溶剂电子密度 solvent_density	0.3340 e/Å³
壳层衬度 contrast_shell	0.0300 e/Å³
CRYSOL 版本 crysol_version	4.1.3

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4. P(r) 距离分布 (GNOM 反演) 4. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax	50.4 Å
Rg (实空间) rg_real	15.11 Å
Rg 误差 (实空间) rg_real_error	0.30 Å
I(0) (实空间) i0_real	3.4900e+06
I(0) 误差 (实空间) i0_real_error	3.6770e+04
Rg (倒空间) rg_reciprocal	15.12 Å
I(0) (倒空间) i0_reciprocal	3490000.0000
解质量估计 total_estimate	0.8831
解质量评级 solution_quality	GOOD a GOOD solution
P(r) 峰数 n_peaks	1
主峰位置 r_peak_primary	49.8 Å
偏度 Skewness skewness	0.218
峰度 Kurtosis kurtosis	-0.317
角度范围 angular_range	— – 0.5000 Å⁻¹
当前正则化参数 α current_alpha	0.0000
最高正则化参数 α highest_alpha	748500.0000
实空间数据点数 n_real_points	80
GNOM 版本 gnom_version	4.1.3
质量判据 quality_criteria	AN1: 0.000; Oscil: 0.835; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.996; Smooth: 0.973

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5. 晶体学与实验 5. Crystallography & Experiment

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6. 实体与聚合物信息 Entities & Polymers (2)

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7. 折叠分类 (SCOP + CATH) 1 domains

CATH v4.4 (1 domains)

结构域编号 domain_id	2yq0A00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily	390 — Epstein Barr virus nuclear antigen-1, DNA-binding domain

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8. 引用文献 (1)

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晶胞边长 a length_a	107.400 Å
晶胞边长 b length_b	107.400 Å
晶胞边长 c length_c	107.400 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	90.00 °
晶胞夹角 γ angle_gamma	90.00 °
晶胞分子数 Z z_pdb	24

空间群 space_group	P 4 3 2
空间群编号 int_tables_number	207
晶系 crystal_system	—

分辨率 resolution	3.911 Å
最低分辨率 resolution_low	33.963 Å
R 因子 r_factor	0.2623
R_work r_work	0.2595
R_free r_free	0.3166

描述 description	ORF 73
分子量 formula_weight	18170.0 kDa
来源方法 src_method	man
拷贝数 entity_count	1

聚合物类型 type	polypeptide(L)
链编号 strand_id	A
原子数 atom_count	951

KSHV LANA (ORF73) C-terminal domain, octameric ring: cubic crystal form

1. 蛋白身份与相关结构 Protein Identity & Related Structures

ORF 73

当前结构中的状态

数据库中的同蛋白其他状态

SAXS 散射曲线 SAXS Profile

P(r) 距离分布 P(r) Distribution

2. 结构基本信息 2. Structure Basics

3. SAXS 参数 (CRYSOL 理论计算) 3. SAXS Parameters (CRYSOL)

4. P(r) 距离分布 (GNOM 反演) 4. P(r) Analysis (GNOM)

5. 晶体学与实验 5. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

6. 实体与聚合物信息 Entities & Polymers (2)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 non-polymer

7. 折叠分类 (SCOP + CATH) 1 domains

CATH v4.4 (1 domains)

8. 引用文献 (1)

9. 文件与曲线 (10)

Files (7)

Curves (3)

来源生物 organism	HUMAN HERPESVIRUS 8 TYPE M
NCBI 分类编号 ncbi_taxonomy_id	435895
宿主生物 host_organism	ESCHERICHIA COLI

描述 description	SULFATE ION
分子量 formula_weight	96.1 kDa
来源方法 src_method	syn
拷贝数 entity_count	1

fit	/app/data/saxs_computation/yq/2yq0/2yq0.fit
pddf	/app/data/pr_computation/yq/2yq0/2yq0.pr.out
profile	/app/data/saxs_computation/yq/2yq0/2yq0.dat