2zsu

Crystal structure of spermidine synthase from Pyrococcus horikoshii OT3, P1 form

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

spermidine synthase

Pyrococcus horikoshii

UniProt O57950

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白同源多聚体 同源多聚体 蛋白 2 1-{4-[(3-aminopropyl)amino]butyl}guanidine × 1 water × 2 与蛋白数一致
2 蛋白同源多聚体 同源多聚体 蛋白 2 1-{4-[(3-aminopropyl)amino]butyl}guanidine × 1 water × 2 与蛋白数一致
3 蛋白同源多聚体 同源多聚体 蛋白 2 1-{4-[(3-aminopropyl)amino]butyl}guanidine × 1 water × 2 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 SPEE_PYRHO
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 1–280; UniProt 1–280 作者链 B; PDB构建体 1–280; UniProt 1–280 作者链 C; PDB构建体 1–280; UniProt 1–280 作者链 D; PDB构建体 1–280; UniProt 1–280 作者链 E; PDB构建体 1–280; UniProt 1–280 作者链 F; PDB构建体 1–280; UniProt 1–280

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id2zsu
沉积日期 deposition_date2008-09-17
结构标题 titleCrystal structure of spermidine synthase from Pyrococcus horikoshii OT3, P1 form
关键词 keywordsspermidine synthase, aminopropylagmatine, Polyamine biosynthesis, Spermidine biosynthesis, Transferase; TRANSFERASE
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

2zsu__assembly_2__model_1

Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

2zsu__assembly_2__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

2zsu__assembly_2__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)25.81 Å
Rg(电子密度)24.62 Å
总 Rg25.73 Å
原子数4407
残基数544
排除体积79559 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 2zsu__assembly_1__model_1 dimeric (2) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
2 1 2zsu__assembly_2__model_1 dimeric (2) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
3 1 2zsu__assembly_3__model_1 dimeric (2) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (3)

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6. 折叠分类 (SCOP + CATH) 18 domains

SCOP 2.08 (6 domains)

结构域编号 domain_idd2zsua_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.66 — S-adenosyl-L-methionine-dependent methyltransferases
超家族 Superfamily superfamilyc.66.1 — S-adenosyl-L-methionine-dependent methyltransferases
家族 Family familyc.66.1.17 — Spermidine synthase
结构域编号 domain_idd2zsub_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.66 — S-adenosyl-L-methionine-dependent methyltransferases
超家族 Superfamily superfamilyc.66.1 — S-adenosyl-L-methionine-dependent methyltransferases
家族 Family familyc.66.1.17 — Spermidine synthase
结构域编号 domain_idd2zsuc_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.66 — S-adenosyl-L-methionine-dependent methyltransferases
超家族 Superfamily superfamilyc.66.1 — S-adenosyl-L-methionine-dependent methyltransferases
家族 Family familyc.66.1.17 — Spermidine synthase
结构域编号 domain_idd2zsud_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.66 — S-adenosyl-L-methionine-dependent methyltransferases
超家族 Superfamily superfamilyc.66.1 — S-adenosyl-L-methionine-dependent methyltransferases
家族 Family familyc.66.1.17 — Spermidine synthase
结构域编号 domain_idd2zsue_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.66 — S-adenosyl-L-methionine-dependent methyltransferases
超家族 Superfamily superfamilyc.66.1 — S-adenosyl-L-methionine-dependent methyltransferases
家族 Family familyc.66.1.17 — Spermidine synthase
结构域编号 domain_idd2zsuf_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.66 — S-adenosyl-L-methionine-dependent methyltransferases
超家族 Superfamily superfamilyc.66.1 — S-adenosyl-L-methionine-dependent methyltransferases
家族 Family familyc.66.1.17 — Spermidine synthase

CATH v4.4 (12 domains)

结构域编号 domain_id2zsuA01
类 Class class2 — Mainly Beta
架构 Architecture architecture30 — Roll
拓扑 Topology topology140 — Spermidine Synthase; Chain: A, domain 2
同源超家族 H-superfamily homologous superfamily10 — Spermidine synthase, tetramerisation domain
结构域编号 domain_id2zsuA02
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily150 — Vaccinia Virus protein VP39
结构域编号 domain_id2zsuB01
类 Class class2 — Mainly Beta
架构 Architecture architecture30 — Roll
拓扑 Topology topology140 — Spermidine Synthase; Chain: A, domain 2
同源超家族 H-superfamily homologous superfamily10 — Spermidine synthase, tetramerisation domain
结构域编号 domain_id2zsuB02
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily150 — Vaccinia Virus protein VP39
结构域编号 domain_id2zsuC01
类 Class class2 — Mainly Beta
架构 Architecture architecture30 — Roll
拓扑 Topology topology140 — Spermidine Synthase; Chain: A, domain 2
同源超家族 H-superfamily homologous superfamily10 — Spermidine synthase, tetramerisation domain
结构域编号 domain_id2zsuC02
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily150 — Vaccinia Virus protein VP39
结构域编号 domain_id2zsuD01
类 Class class2 — Mainly Beta
架构 Architecture architecture30 — Roll
拓扑 Topology topology140 — Spermidine Synthase; Chain: A, domain 2
同源超家族 H-superfamily homologous superfamily10 — Spermidine synthase, tetramerisation domain
结构域编号 domain_id2zsuD02
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily150 — Vaccinia Virus protein VP39
结构域编号 domain_id2zsuE01
类 Class class2 — Mainly Beta
架构 Architecture architecture30 — Roll
拓扑 Topology topology140 — Spermidine Synthase; Chain: A, domain 2
同源超家族 H-superfamily homologous superfamily10 — Spermidine synthase, tetramerisation domain
结构域编号 domain_id2zsuE02
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily150 — Vaccinia Virus protein VP39
结构域编号 domain_id2zsuF01
类 Class class2 — Mainly Beta
架构 Architecture architecture30 — Roll
拓扑 Topology topology140 — Spermidine Synthase; Chain: A, domain 2
同源超家族 H-superfamily homologous superfamily10 — Spermidine synthase, tetramerisation domain
结构域编号 domain_id2zsuF02
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily150 — Vaccinia Virus protein VP39
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7. 引用文献 (1)