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3cif

Crystal Structure of C153S mutant glyceraldehyde 3-phosphate dehydrogenase from Cryptosporidium parvum

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Glyceraldehyde-3-phosphate dehydrogenase

Cryptosporidium parvum

UniProt Q7YYQ9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 4 GLYCERALDEHYDE-3-PHOSPHATE × 4 NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 4 GLYCEROL × 2 MAGNESIUM ION × 2 water × 4 Consistent with protein count
2 Protein homooligomer Homooligomer Protein 2 GLYCERALDEHYDE-3-PHOSPHATE × 2 NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 2 GLYCEROL × 1 MAGNESIUM ION × 1 water × 2 Consistent with protein count
3 Protein homooligomer Homooligomer Protein 2 GLYCERALDEHYDE-3-PHOSPHATE × 2 NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 2 GLYCEROL × 1 MAGNESIUM ION × 1 water × 2 Consistent with protein count
4 Protein homooligomer Homooligomer Protein 2 GLYCERALDEHYDE-3-PHOSPHATE × 2 NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 2 GLYCEROL × 2 MAGNESIUM ION × 1 water × 2 Consistent with protein count
5 Protein homooligomer Homooligomer Protein 2 GLYCERALDEHYDE-3-PHOSPHATE × 2 NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 2 MAGNESIUM ION × 1 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer
1vsu 1vsu 1vsv 1vsv 1vsv 1vsv 3cif 3cif 3cif 3cif

10 assemblies

Homotetramer
1vsu 1vsv 3cif 8pvf

4 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex

None

View Construct and Data Evidence
UniProt name Q7YYQ9_CRYPV
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 21–359； UniProt 1–339 Author chain B； PDBConstruct 21–359； UniProt 1–339 Author chain C； PDBConstruct 21–359； UniProt 1–339 Author chain D； PDBConstruct 21–359； UniProt 1–339

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id3cif
Deposition date deposition_date2008-03-11
Structure title titleCrystal Structure of C153S mutant glyceraldehyde 3-phosphate dehydrogenase from Cryptosporidium parvum
Keywords keywordsdehyrogenase glyceraldehyde 3-phosphate, glycolysis, glycolytic enzyme, Oxidoreductase; OXIDOREDUCTASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

3cif__assembly_5__model_1

Assembly 5 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

3cif__assembly_5__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

3cif__assembly_5__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）28.87 Å
Rg (electron density)28.59 Å
Total Rg29.24 Å
Atom count5145
Residues676
Excluded volume91864 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 3cif__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 3cif__assembly_2__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 3cif__assembly_3__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 3cif__assembly_4__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
5 1 3cif__assembly_5__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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6. Fold Classification (SCOP + CATH) 8 domains

CATH v4.4 (8 domains)

Domain ID domain_id3cifA01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily720 — NAD(P)-binding Rossmann-like Domain
Domain ID domain_id3cifA02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology360 — Dihydrodipicolinate Reductase; domain 2
Homologous superfamily homologous superfamily10 — Dihydrodipicolinate Reductase; domain 2
Domain ID domain_id3cifB01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily720 — NAD(P)-binding Rossmann-like Domain
Domain ID domain_id3cifB02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology360 — Dihydrodipicolinate Reductase; domain 2
Homologous superfamily homologous superfamily10 — Dihydrodipicolinate Reductase; domain 2
Domain ID domain_id3cifC01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily720 — NAD(P)-binding Rossmann-like Domain
Domain ID domain_id3cifC02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology360 — Dihydrodipicolinate Reductase; domain 2
Homologous superfamily homologous superfamily10 — Dihydrodipicolinate Reductase; domain 2
Domain ID domain_id3cifD01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily720 — NAD(P)-binding Rossmann-like Domain
Domain ID domain_id3cifD02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology360 — Dihydrodipicolinate Reductase; domain 2
Homologous superfamily homologous superfamily10 — Dihydrodipicolinate Reductase; domain 2
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7. Citations (1)