Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白异源复合物 | 异源复合物 | 蛋白 4 | Vacuolar protein-sorting-associated protein 36 × 1 （Q86VN1） Vacuolar protein-sorting-associated protein 25 × 2 （Q9BRG1） water × 4 | 与蛋白数一致 |
| UniProt名称 | SNF8_HUMAN |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 1–234； UniProt 25–258 |
Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白异源复合物 | 异源复合物 | 蛋白 4 | Vacuolar-sorting protein SNF8 × 1 （Q96H20） Vacuolar protein-sorting-associated protein 25 × 2 （Q9BRG1） water × 4 | 与蛋白数一致 |
| UniProt名称 | VPS36_HUMAN |
| Isoform | — |
| PDB实体 | 2 |
| 链与序列区间 | 作者链 B； PDB构建体 1–218； UniProt 169–386 |
Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白异源复合物 | 异源复合物 | 蛋白 4 | Vacuolar-sorting protein SNF8 × 1 （Q96H20） Vacuolar protein-sorting-associated protein 36 × 1 （Q86VN1） water × 4 | 与蛋白数一致 |
| UniProt名称 | VPS25_HUMAN |
| Isoform | — |
| PDB实体 | 3 |
| 链与序列区间 | 作者链 C； PDB构建体 1–176； UniProt 1–176 作者链 D； PDB构建体 1–176； UniProt 1–176 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 3cuq |
| 沉积日期 deposition_date | 2008-04-16 |
| 结构标题 title | Integrated structural and functional model of the human ESCRT-II complex |
| 关键词 keywords | ESCRT, Sorting, MBV, vps, Nucleus, Protein transport, Transcription, Transcription regulation, Transport, Endosome, Lipid-binding; PROTEIN TRANSPORT |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 32.96 Å |
| Rg（电子密度） | 32.36 Å |
| 总 Rg | 32.89 Å |
| 原子数 | 5592 |
| 残基数 | 693 |
| 排除体积 | 100440 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d3cuqa1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.4 — DNA/RNA-binding 3-helical bundle |
| 超家族 Superfamily superfamily | a.4.5 — 'Winged helix' DNA-binding domain |
| 家族 Family family | a.4.5.0 — automated matches |
| 结构域编号 domain_id | d3cuqa2 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.4 — DNA/RNA-binding 3-helical bundle |
| 超家族 Superfamily superfamily | a.4.5 — 'Winged helix' DNA-binding domain |
| 家族 Family family | a.4.5.0 — automated matches |
| 结构域编号 domain_id | 3cuqA02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 10 — Arc Repressor Mutant, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
| 结构域编号 domain_id | 3cuqA03 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 10 — Arc Repressor Mutant, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
| 结构域编号 domain_id | 3cuqB01 |
| 类 Class class | 6 — Special |
| 架构 Architecture architecture | 10 — Helix non-globular |
| 拓扑 Topology topology | 140 — Helix Hairpins |
| 同源超家族 H-superfamily homologous superfamily | 260 — |
| 结构域编号 domain_id | 3cuqB02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 10 — Arc Repressor Mutant, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
| 结构域编号 domain_id | 3cuqB03 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 10 — Arc Repressor Mutant, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
| 结构域编号 domain_id | 3cuqC01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 10 — Arc Repressor Mutant, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 570 — "Winged helix" DNA-binding domain. Chain C. Domain 1 |
| 结构域编号 domain_id | 3cuqC02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 10 — Arc Repressor Mutant, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
| 结构域编号 domain_id | 3cuqD00 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 10 — Arc Repressor Mutant, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 570 — "Winged helix" DNA-binding domain. Chain C. Domain 1 |