3e90
West Nile vi rus NS2B-NS3protease in complexed with inhibitor Naph-KKR-H
1. Protein Identity and Related Structures Protein Identity & Related Structures
No usable UniProt protein identity is available for this entry.
The relationship tables retain this entry's assembly and composition data, but cross-PDB links for the same protein cannot be established reliably without a unified protein identity.
Assembly Composition of the Current Entry
| Assembly | Physical composition | Protein state | 蛋白 / DNA / RNA / 其他Polymer | Data consistency |
|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | 2 / 0 / 0 / 0 | Consistent with protein count |
| 2 | Protein heterocomplex | Heteromer | 2 / 0 / 0 / 0 | Consistent with protein count |
| 3 | Protein heterocomplex | Heteromer | 4 / 0 / 0 / 0 | Consistent with protein count |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
2. Structure Basics 2. Structure Basics
| Entry ID entry_id | 3e90 |
| Deposition date deposition_date | 2008-08-21 |
| Structure title title | West Nile vi rus NS2B-NS3protease in complexed with inhibitor Naph-KKR-H |
| Keywords keywords | ;West Nile virus, NS3 protease, trypsin-like serine protease, protease inhibitor, catalytic histidine, induced fit, ATP-binding, Capsid protein, Helicase, Hydrolase, Nucleotide-binding, RNA replication, Transmembrane, Virion ;; HYDROLASE |
| Experimental Method method | X-RAY DIFFRACTION |
3. Official assembly/model SAXS Official SAXS Profiles
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
3e90__assembly_2__model_1
Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
3e90__assembly_2__model_1 | I(q)
3e90__assembly_2__model_1 | P(r) · Pending
| Rg（Guinier） | 17.66 Å |
| Rg (electron density) | 16.41 Å |
| Total Rg | 17.53 Å |
| Atom count | 1635 |
| Residues | 208 |
| Excluded volume | 28917 ų |
| Maximum q | 0.500 Å⁻¹ |
| Assembly | Model | Structure unit | Oligomeric description | Status | CRYSOL | Actions |
|---|---|---|---|---|---|---|
| 1 | 1 | 3e90__assembly_1__model_1 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 2 | 1 | 3e90__assembly_2__model_1 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 3 | 1 | 3e90__assembly_3__model_1 |
tetrameric （4） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
4. Crystallography and Experiment 4. Crystallography & Experiment
5. Entities and Polymers Entities & Polymers (4)
6. Fold Classification (SCOP + CATH) 10 domains
SCOP 2.08 (6 domains)
| Domain ID domain_id | d3e90a_ |
| Class class | g — Small proteins |
| Fold Fold fold | g.96 — Flavivirus non-structural protein NS2B-like |
| Superfamily Superfamily superfamily | g.96.1 — Flavivirus non-structural protein NS2B-like |
| Family Family family | g.96.1.1 — Flavivirus non-structural protein NS2B-like |
| Domain ID domain_id | d3e90b1 |
| Class class | b — All beta proteins |
| Fold Fold fold | b.47 — Trypsin-like serine proteases |
| Superfamily Superfamily superfamily | b.47.1 — Trypsin-like serine proteases |
| Family Family family | b.47.1.3 — Viral proteases |
| Domain ID domain_id | d3e90b2 |
| Class class | l — Artifacts |
| Fold Fold fold | l.1 — Tags |
| Superfamily Superfamily superfamily | l.1.1 — Tags |
| Family Family family | l.1.1.1 — Tags |
| Domain ID domain_id | d3e90c_ |
| Class class | g — Small proteins |
| Fold Fold fold | g.96 — Flavivirus non-structural protein NS2B-like |
| Superfamily Superfamily superfamily | g.96.1 — Flavivirus non-structural protein NS2B-like |
| Family Family family | g.96.1.1 — Flavivirus non-structural protein NS2B-like |
| Domain ID domain_id | d3e90d1 |
| Class class | b — All beta proteins |
| Fold Fold fold | b.47 — Trypsin-like serine proteases |
| Superfamily Superfamily superfamily | b.47.1 — Trypsin-like serine proteases |
| Family Family family | b.47.1.3 — Viral proteases |
| Domain ID domain_id | d3e90d2 |
| Class class | l — Artifacts |
| Fold Fold fold | l.1 — Tags |
| Superfamily Superfamily superfamily | l.1.1 — Tags |
| Family Family family | l.1.1.1 — Tags |
CATH v4.4 (4 domains)
| Domain ID domain_id | 3e90B01 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 40 — Beta Barrel |
| Topology topology | 10 — Thrombin, subunit H |
| Homologous superfamily homologous superfamily | 120 — |
| Domain ID domain_id | 3e90B02 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 40 — Beta Barrel |
| Topology topology | 10 — Thrombin, subunit H |
| Homologous superfamily homologous superfamily | 10 — Trypsin-like serine proteases |
| Domain ID domain_id | 3e90D01 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 40 — Beta Barrel |
| Topology topology | 10 — Thrombin, subunit H |
| Homologous superfamily homologous superfamily | 120 — |
| Domain ID domain_id | 3e90D02 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 40 — Beta Barrel |
| Topology topology | 10 — Thrombin, subunit H |
| Homologous superfamily homologous superfamily | 10 — Trypsin-like serine proteases |