Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白同源多聚体 | 同源多聚体 | 蛋白 2 | GLYCEROL × 2 water × 2 | 与蛋白数一致 |
| UniProt名称 | MASP1_HUMAN |
| Isoform | — |
| PDB实体 | 1, 2 |
| 链与序列区间 | 作者链 A； PDB构建体 5–155； UniProt 298–448 作者链 B； PDB构建体 1–251； UniProt 449–699 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 3gov |
| 沉积日期 deposition_date | 2009-03-20 |
| 结构标题 title | Crystal structure of the catalytic region of human MASP-1 |
| 关键词 keywords | ;Complement, serine protease, beta barrel, Hydrolase, Hydroxylation, Immune response, Innate immunity, Sushi, Coagulation, Complement pathway, Disulfide bond, EGF-like domain, Glycoprotein, Protease ;; HYDROLASE |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 31.79 Å |
| Rg（电子密度） | 32.83 Å |
| 总 Rg | 32.88 Å |
| 原子数 | 3077 |
| 残基数 | 398 |
| 排除体积 | 54726 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d3gova1 |
| 类 Class class | g — Small proteins |
| 折叠类型 Fold fold | g.18 — Complement control module/SCR domain |
| 超家族 Superfamily superfamily | g.18.1 — Complement control module/SCR domain |
| 家族 Family family | g.18.1.0 — automated matches |
| 结构域编号 domain_id | d3gova2 |
| 类 Class class | g — Small proteins |
| 折叠类型 Fold fold | g.18 — Complement control module/SCR domain |
| 超家族 Superfamily superfamily | g.18.1 — Complement control module/SCR domain |
| 家族 Family family | g.18.1.0 — automated matches |
| 结构域编号 domain_id | d3govb_ |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.47 — Trypsin-like serine proteases |
| 超家族 Superfamily superfamily | b.47.1 — Trypsin-like serine proteases |
| 家族 Family family | b.47.1.0 — automated matches |
| 结构域编号 domain_id | 3govA01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 10 — Ribbon |
| 拓扑 Topology topology | 70 — Complement Module; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Complement Module, domain 1 |
| 结构域编号 domain_id | 3govA02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 10 — Ribbon |
| 拓扑 Topology topology | 70 — Complement Module; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Complement Module, domain 1 |
| 结构域编号 domain_id | 3govB01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 10 — Thrombin, subunit H |
| 同源超家族 H-superfamily homologous superfamily | 10 — Trypsin-like serine proteases |
| 结构域编号 domain_id | 3govB02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 10 — Thrombin, subunit H |
| 同源超家族 H-superfamily homologous superfamily | 10 — Trypsin-like serine proteases |