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3h5y

Norovirus polymerase+primer/template+CTP complex at 6 mM MnCl2

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

RNA dependent RNA polymerase

Norwalk virus

UniProt Q70ET3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Monomer Protein 1 RNA 2 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3' × 1 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3' × 1 MANGANESE (II) ION × 4 CYTIDINE-5'-TRIPHOSPHATE × 1 GLYCEROL × 4 water × 3 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer
1sh0 1sh0 1sh2 1sh3 1sh3

5 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3bsn 3bso 3h5x 3h5y 4qpx 5tsn

6 assemblies

View Construct and Data Evidence
UniProt name Q70ET3_9CALI
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–510； UniProt 329–838

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id3h5y
Deposition date deposition_date2009-04-22
Structure title titleNorovirus polymerase+primer/template+CTP complex at 6 mM MnCl2
Keywords keywords;caliciviruses, viral RNA polymerase, Hydrolase, Nucleotide-binding, Nucleotidyltransferase, Protease, RNA replication, RNA-directed RNA polymerase, Thiol protease, Transferase, Transferase-RNA COMPLEX ;; Transferase/RNA
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

3h5y__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

3h5y__assembly_1__model_1 | I(q)

10-2 10-1 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

3h5y__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）23.23 Å
Rg (electron density)22.86 Å
Total Rg23.60 Å
Atom count4126
Residues490
Excluded volume72382 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 3h5y__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (7)

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd3h5ya_
Class classe — Multi-domain proteins (alpha and beta)
Fold Fold folde.8 — DNA/RNA polymerases
Superfamily Superfamily superfamilye.8.1 — DNA/RNA polymerases
Family Family familye.8.1.4 — RNA-dependent RNA-polymerase

CATH v4.4 (3 domains)

Domain ID domain_id3h5yA02
Class class6 — Special
Architecture architecture10 — Helix non-globular
Topology topology250 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily3230 —
Domain ID domain_id3h5yA03
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily270 — Reverse transcriptase/Diguanylate cyclase domain
Domain ID domain_id3h5yA04
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology960 — Mitochondrial Import Receptor Subunit Tom20; Chain A
Homologous superfamily homologous superfamily20 —
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7. Citations (1)