Hepatitis C virus
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白–DNA | 单体 | 蛋白 1 DNA 1 | 5'-D(*TP*TP*TP*TP*TP*T)-3' × 1 water × 2 | 与全部聚合物一致 |
| 2 | 蛋白–DNA | 单体 | 蛋白 1 DNA 1 | 5'-D(*TP*TP*TP*TP*TP*T)-3' × 1 water × 2 | 与全部聚合物一致 |
| UniProt名称 | POLG_HCVCO |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 1–436； UniProt 1215–1650 作者链 B； PDB构建体 1–436； UniProt 1215–1650 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 3kqk |
| 沉积日期 deposition_date | 2009-11-17 |
| 结构标题 title | Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism |
| 关键词 keywords | helicase-substrate binary complex, HCV, NS3 protein, helicase, DNA-binding, HYDROLASE-DNA complex; HYDROLASE/DNA |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 23.95 Å |
| Rg（电子密度） | 23.30 Å |
| 总 Rg | 24.06 Å |
| 原子数 | 3392 |
| 残基数 | 442 |
| 排除体积 | 60176 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d3kqka1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.37 — P-loop containing nucleoside triphosphate hydrolases |
| 超家族 Superfamily superfamily | c.37.1 — P-loop containing nucleoside triphosphate hydrolases |
| 家族 Family family | c.37.1.14 — RNA helicase |
| 结构域编号 domain_id | d3kqka2 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.37 — P-loop containing nucleoside triphosphate hydrolases |
| 超家族 Superfamily superfamily | c.37.1 — P-loop containing nucleoside triphosphate hydrolases |
| 家族 Family family | c.37.1.14 — RNA helicase |
| 结构域编号 domain_id | d3kqkb1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.37 — P-loop containing nucleoside triphosphate hydrolases |
| 超家族 Superfamily superfamily | c.37.1 — P-loop containing nucleoside triphosphate hydrolases |
| 家族 Family family | c.37.1.14 — RNA helicase |
| 结构域编号 domain_id | d3kqkb2 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.37 — P-loop containing nucleoside triphosphate hydrolases |
| 超家族 Superfamily superfamily | c.37.1 — P-loop containing nucleoside triphosphate hydrolases |
| 家族 Family family | c.37.1.14 — RNA helicase |
| 结构域编号 domain_id | 3kqkA01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 300 — P-loop containing nucleotide triphosphate hydrolases |
| 结构域编号 domain_id | 3kqkA02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 300 — P-loop containing nucleotide triphosphate hydrolases |
| 结构域编号 domain_id | 3kqkA03 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 820 — RNA Helicase; Chain A, domain 3 |
| 同源超家族 H-superfamily homologous superfamily | 10 — RNA Helicase Chain A , domain 3 |
| 结构域编号 domain_id | 3kqkB01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 300 — P-loop containing nucleotide triphosphate hydrolases |
| 结构域编号 domain_id | 3kqkB02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 300 — P-loop containing nucleotide triphosphate hydrolases |
| 结构域编号 domain_id | 3kqkB03 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 820 — RNA Helicase; Chain A, domain 3 |
| 同源超家族 H-superfamily homologous superfamily | 10 — RNA Helicase Chain A , domain 3 |