Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白单体 | 单体 | 蛋白 1 | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 water × 1 | 与蛋白数一致 |
| 2 | 蛋白单体 | 单体 | 蛋白 1 | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 water × 1 | 与蛋白数一致 |
| UniProt名称 | GRP78_HUMAN |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 3–384； UniProt 26–407 作者链 B； PDB构建体 3–384； UniProt 26–407 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 3ldo |
| 沉积日期 deposition_date | 2010-01-13 |
| 结构标题 title | Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with AMPPNP |
| 关键词 keywords | ;GRP78, HSP70, HSC70, CHAPERONE, HEAT SHOCK, PROTEIN FOLDING, ATP-BINDING, ADENOSINE, NUCLEOSIDE, NUCLEOTIDE-BINDING, STRESS RESPONSE, SMALL MOLECULE INHIBITOR, SELECTIVITY, Endoplasmic reticulum, Phosphoprotein ;; CHAPERONE |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 22.14 Å |
| Rg（电子密度） | 21.14 Å |
| 总 Rg | 22.02 Å |
| 原子数 | 2971 |
| 残基数 | 382 |
| 排除体积 | 52701 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d3ldoa1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.55 — Ribonuclease H-like motif |
| 超家族 Superfamily superfamily | c.55.1 — Actin-like ATPase domain |
| 家族 Family family | c.55.1.0 — automated matches |
| 结构域编号 domain_id | d3ldoa2 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.55 — Ribonuclease H-like motif |
| 超家族 Superfamily superfamily | c.55.1 — Actin-like ATPase domain |
| 家族 Family family | c.55.1.0 — automated matches |
| 结构域编号 domain_id | d3ldob1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.55 — Ribonuclease H-like motif |
| 超家族 Superfamily superfamily | c.55.1 — Actin-like ATPase domain |
| 家族 Family family | c.55.1.0 — automated matches |
| 结构域编号 domain_id | d3ldob2 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.55 — Ribonuclease H-like motif |
| 超家族 Superfamily superfamily | c.55.1 — Actin-like ATPase domain |
| 家族 Family family | c.55.1.0 — automated matches |
| 结构域编号 domain_id | 3ldoA01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 420 — Nucleotidyltransferase; domain 5 |
| 同源超家族 H-superfamily homologous superfamily | 40 — ATPase, nucleotide binding domain |
| 结构域编号 domain_id | 3ldoA02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 30 — Defensin A-like |
| 同源超家族 H-superfamily homologous superfamily | 30 — |
| 结构域编号 domain_id | 3ldoA03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 420 — Nucleotidyltransferase; domain 5 |
| 同源超家族 H-superfamily homologous superfamily | 40 — ATPase, nucleotide binding domain |
| 结构域编号 domain_id | 3ldoA04 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 640 — Actin; Chain A, domain 4 |
| 同源超家族 H-superfamily homologous superfamily | 10 — ATPase, substrate binding domain, subdomain 4 |
| 结构域编号 domain_id | 3ldoB01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 420 — Nucleotidyltransferase; domain 5 |
| 同源超家族 H-superfamily homologous superfamily | 40 — ATPase, nucleotide binding domain |
| 结构域编号 domain_id | 3ldoB02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 30 — Defensin A-like |
| 同源超家族 H-superfamily homologous superfamily | 30 — |
| 结构域编号 domain_id | 3ldoB03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 420 — Nucleotidyltransferase; domain 5 |
| 同源超家族 H-superfamily homologous superfamily | 40 — ATPase, nucleotide binding domain |
| 结构域编号 domain_id | 3ldoB04 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 640 — Actin; Chain A, domain 4 |
| 同源超家族 H-superfamily homologous superfamily | 10 — ATPase, substrate binding domain, subdomain 4 |