3m2l

Crystal structure of the M113F mutant of alpha-hemolysin

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Alpha-hemolysin

Staphylococcus aureus

UniProt P09616

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白同源多聚体 同源多聚体 蛋白 7 water × 7 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 HLA_STAAU
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 2–294; UniProt 27–319 作者链 B; PDB构建体 2–294; UniProt 27–319 作者链 C; PDB构建体 2–294; UniProt 27–319 作者链 D; PDB构建体 2–294; UniProt 27–319 作者链 E; PDB构建体 2–294; UniProt 27–319 作者链 F; PDB构建体 2–294; UniProt 27–319 作者链 G; PDB构建体 2–294; UniProt 27–319

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id3m2l
沉积日期 deposition_date2010-03-07
结构标题 titleCrystal structure of the M113F mutant of alpha-hemolysin
关键词 keywordsbeta barrel, pore-forming toxin, Cytolysis, Hemolysis, Secreted, Toxin; TOXIN
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

3m2l__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

3m2l__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

3m2l__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)39.75 Å
Rg(电子密度)38.45 Å
总 Rg39.09 Å
原子数16431
残基数2051
排除体积289290 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 3m2l__assembly_1__model_1 heptameric (7) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (2)

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6. 折叠分类 (SCOP + CATH) 14 domains

SCOP 2.08 (7 domains)

结构域编号 domain_idd3m2la_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.6 — Leukocidin-like
超家族 Superfamily superfamilyf.6.1 — Leukocidin-like
家族 Family familyf.6.1.1 — Leukocidin (pore-forming toxin)
结构域编号 domain_idd3m2lb_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.6 — Leukocidin-like
超家族 Superfamily superfamilyf.6.1 — Leukocidin-like
家族 Family familyf.6.1.1 — Leukocidin (pore-forming toxin)
结构域编号 domain_idd3m2lc_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.6 — Leukocidin-like
超家族 Superfamily superfamilyf.6.1 — Leukocidin-like
家族 Family familyf.6.1.1 — Leukocidin (pore-forming toxin)
结构域编号 domain_idd3m2ld_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.6 — Leukocidin-like
超家族 Superfamily superfamilyf.6.1 — Leukocidin-like
家族 Family familyf.6.1.1 — Leukocidin (pore-forming toxin)
结构域编号 domain_idd3m2le_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.6 — Leukocidin-like
超家族 Superfamily superfamilyf.6.1 — Leukocidin-like
家族 Family familyf.6.1.1 — Leukocidin (pore-forming toxin)
结构域编号 domain_idd3m2lf_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.6 — Leukocidin-like
超家族 Superfamily superfamilyf.6.1 — Leukocidin-like
家族 Family familyf.6.1.1 — Leukocidin (pore-forming toxin)
结构域编号 domain_idd3m2lg_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.6 — Leukocidin-like
超家族 Superfamily superfamilyf.6.1 — Leukocidin-like
家族 Family familyf.6.1.1 — Leukocidin (pore-forming toxin)

CATH v4.4 (7 domains)

结构域编号 domain_id3m2lA00
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology240 — Leukocidin-like
同源超家族 H-superfamily homologous superfamily10 — Leukocidin/porin MspA
结构域编号 domain_id3m2lB00
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology240 — Leukocidin-like
同源超家族 H-superfamily homologous superfamily10 — Leukocidin/porin MspA
结构域编号 domain_id3m2lC00
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology240 — Leukocidin-like
同源超家族 H-superfamily homologous superfamily10 — Leukocidin/porin MspA
结构域编号 domain_id3m2lD00
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology240 — Leukocidin-like
同源超家族 H-superfamily homologous superfamily10 — Leukocidin/porin MspA
结构域编号 domain_id3m2lE00
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology240 — Leukocidin-like
同源超家族 H-superfamily homologous superfamily10 — Leukocidin/porin MspA
结构域编号 domain_id3m2lF00
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology240 — Leukocidin-like
同源超家族 H-superfamily homologous superfamily10 — Leukocidin/porin MspA
结构域编号 domain_id3m2lG00
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology240 — Leukocidin-like
同源超家族 H-superfamily homologous superfamily10 — Leukocidin/porin MspA
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7. 引用文献 (1)