Mycobacterium tuberculosis
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白同源多聚体 | 同源多聚体 | 蛋白 8 | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER × 8 NICOTINIC ACID ADENINE DINUCLEOTIDE × 8 GLYCEROL × 4 water × 8 | 与蛋白数一致 |
| UniProt名称 | NADE_MYCTU |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 2–680； UniProt 1–679 作者链 B； PDB构建体 2–680； UniProt 1–679 作者链 C； PDB构建体 2–680； UniProt 1–679 作者链 D； PDB构建体 2–680； UniProt 1–679 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 3seq |
| 沉积日期 deposition_date | 2011-06-10 |
| 结构标题 title | Crystal structure of C176A mutant of glutamine-dependent NAD+ synthetase from M. tuberculosis in complex with AMPCPP and NaAD+ |
| 关键词 keywords | ;Glutamine-amidotransferase, Glutaminase, Glutamine-dependent NAD+ synthetase, Ligase, Ammonia tunneling, ATP binding, NAD, Nucleotide binding ;; LIGASE |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 55.03 Å |
| Rg（电子密度） | 54.70 Å |
| 总 Rg | 54.85 Å |
| 原子数 | 40942 |
| 残基数 | 5238 |
| 排除体积 | 722010 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | 3seqA01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 60 — 4-Layer Sandwich |
| 拓扑 Topology topology | 110 — Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase |
| 同源超家族 H-superfamily homologous superfamily | 10 — Carbon-nitrogen hydrolase |
| 结构域编号 domain_id | 3seqA02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 620 — HUPs |
| 结构域编号 domain_id | 3seqA03 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 10 — Arc Repressor Mutant, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 1140 — Glutamine-dependent NAD+ synthetase, C-terminal domain |
| 结构域编号 domain_id | 3seqB01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 60 — 4-Layer Sandwich |
| 拓扑 Topology topology | 110 — Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase |
| 同源超家族 H-superfamily homologous superfamily | 10 — Carbon-nitrogen hydrolase |
| 结构域编号 domain_id | 3seqB02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 620 — HUPs |
| 结构域编号 domain_id | 3seqB03 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 10 — Arc Repressor Mutant, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 1140 — Glutamine-dependent NAD+ synthetase, C-terminal domain |
| 结构域编号 domain_id | 3seqC01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 60 — 4-Layer Sandwich |
| 拓扑 Topology topology | 110 — Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase |
| 同源超家族 H-superfamily homologous superfamily | 10 — Carbon-nitrogen hydrolase |
| 结构域编号 domain_id | 3seqC02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 620 — HUPs |
| 结构域编号 domain_id | 3seqC03 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 10 — Arc Repressor Mutant, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 1140 — Glutamine-dependent NAD+ synthetase, C-terminal domain |
| 结构域编号 domain_id | 3seqD01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 60 — 4-Layer Sandwich |
| 拓扑 Topology topology | 110 — Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase |
| 同源超家族 H-superfamily homologous superfamily | 10 — Carbon-nitrogen hydrolase |
| 结构域编号 domain_id | 3seqD02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 620 — HUPs |
| 结构域编号 domain_id | 3seqD03 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 10 — Arc Repressor Mutant, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 1140 — Glutamine-dependent NAD+ synthetase, C-terminal domain |