3w5a

Crystal structure of the calcium pump and sarcolipin from rabbit fast twitch skeletal muscle in the E1.Mg2+ state

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

SERCA1a

物种未注明

UniProt B6CAM1

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 3 Sarcolipin × 1 (P42532) ;2',3'-O-[(1r)-2,4,6-trinitrocyclohexa-2,5-diene-1,1-diyl]adenosine 5'-(dihydrogen phosphate) ; × 2 PHOSPHATIDYLETHANOLAMINE × 5 MAGNESIUM ION × 4 SODIUM ION × 2 water × 2 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 B6CAM1_RABIT
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 2–995; UniProt 1–994 作者链 B; PDB构建体 2–995; UniProt 1–994

Sarcolipin

物种未注明

UniProt P42532

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 3 SERCA1a × 2 (B6CAM1) ;2',3'-O-[(1r)-2,4,6-trinitrocyclohexa-2,5-diene-1,1-diyl]adenosine 5'-(dihydrogen phosphate) ; × 2 PHOSPHATIDYLETHANOLAMINE × 5 MAGNESIUM ION × 4 SODIUM ION × 2 water × 2 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 SARCO_RABIT
Isoform —
PDB实体 2
链与序列区间 作者链 C; PDB构建体 1–31; UniProt 1–31

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id3w5a
沉积日期 deposition_date2013-01-27
结构标题 titleCrystal structure of the calcium pump and sarcolipin from rabbit fast twitch skeletal muscle in the E1.Mg2+ state
关键词 keywords;P-TYPE ATPASE, HYDROLASE, CALCIUM TRANSPORT, CALCIUM BINDING, ATP BINDING, ENDOPLASMIC RETICULUM, SARCOLIPIN, METAL TRANSPORT-MEMBRANE PROTEIN complex ;; METAL TRANSPORT/MEMBRANE PROTEIN
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

3w5a__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

3w5a__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

3w5a__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)60.93 Å
Rg(电子密度)60.99 Å
总 Rg61.00 Å
原子数15790
残基数2019
排除体积283440 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 3w5a__assembly_1__model_1 trimeric (3) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (7)

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6. 折叠分类 (SCOP + CATH) 8 domains

CATH v4.4 (8 domains)

结构域编号 domain_id3w5aA01
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology150 — Calcium-transporting ATPase, cytoplasmic transduction domain A
同源超家族 H-superfamily homologous superfamily10 — Calcium-transporting ATPase, cytoplasmic transduction domain A
结构域编号 domain_id3w5aA02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1110 — Calcium-transporting ATPase, transmembrane domain
同源超家族 H-superfamily homologous superfamily10 — Calcium-transporting ATPase, transmembrane domain
结构域编号 domain_id3w5aA03
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1000 — HAD superfamily/HAD-like
结构域编号 domain_id3w5aA04
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology1110 — Calcium-transporting ATPase, cytoplasmic domain N
同源超家族 H-superfamily homologous superfamily10 — Calcium-transporting ATPase, cytoplasmic domain N
结构域编号 domain_id3w5aB01
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology150 — Calcium-transporting ATPase, cytoplasmic transduction domain A
同源超家族 H-superfamily homologous superfamily10 — Calcium-transporting ATPase, cytoplasmic transduction domain A
结构域编号 domain_id3w5aB02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1110 — Calcium-transporting ATPase, transmembrane domain
同源超家族 H-superfamily homologous superfamily10 — Calcium-transporting ATPase, transmembrane domain
结构域编号 domain_id3w5aB03
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1000 — HAD superfamily/HAD-like
结构域编号 domain_id3w5aB04
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology1110 — Calcium-transporting ATPase, cytoplasmic domain N
同源超家族 H-superfamily homologous superfamily10 — Calcium-transporting ATPase, cytoplasmic domain N
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7. 引用文献 (1)