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4c3b

HRSV M2-1, P21 crystal form

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

MATRIX PROTEIN 2-1

HUMAN RESPIRATORY SYNCYTIAL VIRUS

UniProt P04545

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 4 ZINC ION × 4 water × 4 Consistent with protein count
2 Protein homooligomer Homooligomer Protein 4 ZINC ION × 4 water × 4 Consistent with protein count
3 Protein homooligomer Homooligomer Protein 4 ZINC ION × 4 water × 4 Consistent with protein count
4 Protein homooligomer Homooligomer Protein 4 ZINC ION × 4 water × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer
4c3b 4c3b 4c3b 4c3b 4c3d 4c3d 4c3e 4c3e 4c3e 4c3e

10 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
6g0y 6pzq

2 assemblies

View Construct and Data Evidence
UniProt name M21_HRSVA
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 6–199； UniProt 1–194 Author chain B； PDBConstruct 6–199； UniProt 1–194 Author chain C； PDBConstruct 6–199； UniProt 1–194 Author chain D； PDBConstruct 6–199； UniProt 1–194 Author chain E； PDBConstruct 6–199； UniProt 1–194 Author chain F； PDBConstruct 6–199； UniProt 1–194 Author chain G； PDBConstruct 6–199； UniProt 1–194 Author chain H； PDBConstruct 6–199； UniProt 1–194 Author chain I； PDBConstruct 6–199； UniProt 1–194 Author chain J； PDBConstruct 6–199； UniProt 1–194 Author chain K； PDBConstruct 6–199； UniProt 1–194 Author chain L； PDBConstruct 6–199； UniProt 1–194 Author chain M； PDBConstruct 6–199； UniProt 1–194 Author chain N； PDBConstruct 6–199； UniProt 1–194 Author chain O； PDBConstruct 6–199； UniProt 1–194 Author chain P； PDBConstruct 6–199； UniProt 1–194

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id4c3b
Deposition date deposition_date2013-08-22
Structure title titleHRSV M2-1, P21 crystal form
Keywords keywordsVIRAL PROTEIN, HRSV, M2-1; VIRAL PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

4c3b__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

4c3b__assembly_1__model_1 | I(q)

10-2 10-1 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

4c3b__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）27.58 Å
Rg (electron density)26.74 Å
Total Rg27.60 Å
Atom count5231
Residues644
Excluded volume93628 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 4c3b__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 4c3b__assembly_2__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 4c3b__assembly_3__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 4c3b__assembly_4__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 16 domains

CATH v4.4 (16 domains)

Domain ID domain_id4c3bA00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily1350 — Pneumovirus matrix protein 2 (M2), zinc-binding domain
Domain ID domain_id4c3bB00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily1350 — Pneumovirus matrix protein 2 (M2), zinc-binding domain
Domain ID domain_id4c3bC00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily1350 — Pneumovirus matrix protein 2 (M2), zinc-binding domain
Domain ID domain_id4c3bD00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily1350 — Pneumovirus matrix protein 2 (M2), zinc-binding domain
Domain ID domain_id4c3bE00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily1350 — Pneumovirus matrix protein 2 (M2), zinc-binding domain
Domain ID domain_id4c3bF00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily1350 — Pneumovirus matrix protein 2 (M2), zinc-binding domain
Domain ID domain_id4c3bG00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily1350 — Pneumovirus matrix protein 2 (M2), zinc-binding domain
Domain ID domain_id4c3bH00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily1350 — Pneumovirus matrix protein 2 (M2), zinc-binding domain
Domain ID domain_id4c3bI00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily1350 — Pneumovirus matrix protein 2 (M2), zinc-binding domain
Domain ID domain_id4c3bJ00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily1350 — Pneumovirus matrix protein 2 (M2), zinc-binding domain
Domain ID domain_id4c3bK00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily1350 — Pneumovirus matrix protein 2 (M2), zinc-binding domain
Domain ID domain_id4c3bL00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily1350 — Pneumovirus matrix protein 2 (M2), zinc-binding domain
Domain ID domain_id4c3bM00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily1350 — Pneumovirus matrix protein 2 (M2), zinc-binding domain
Domain ID domain_id4c3bN00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily1350 — Pneumovirus matrix protein 2 (M2), zinc-binding domain
Domain ID domain_id4c3bO00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily1350 — Pneumovirus matrix protein 2 (M2), zinc-binding domain
Domain ID domain_id4c3bP00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily1350 — Pneumovirus matrix protein 2 (M2), zinc-binding domain
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7. Citations (1)