HOMO SAPIENS
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein homooligomer | Homooligomer | Protein 2 | ZINC ION × 8 FORMIC ACID × 8 water × 2 | Consistent with protein count |
| UniProt name | PYR1_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 3–393； UniProt 1456–1846 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 4c6c |
| Deposition date deposition_date | 2013-09-18 |
| Structure title title | Crystal structure of the dihydroorotase domain of human CAD in apo- form obtained recombinantly from HEK293 cells. |
| Keywords keywords | HYDROLASE, DE NOVO PYRIMIDINE BIOSYNTHESIS, AMIDOHYDROLASE SUPERFAMILY, METALLOENZYME, ZINC BINDING, HISTIDINATE ANION; HYDROLASE |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 29.95 Å |
| Rg (electron density) | 29.72 Å |
| Total Rg | 30.17 Å |
| Atom count | 11114 |
| Residues | 722 |
| Excluded volume | 99067 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | 4c6cA00 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 20 — Alpha-Beta Barrel |
| Topology topology | 20 — TIM Barrel |
| Homologous superfamily homologous superfamily | 140 — Metal-dependent hydrolases |