Pyrococcus furiosus
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein monomer | Monomer | Protein 1 | ZINC ION × 1 | Consistent with protein count |
| UniProt name | Q8U1S6_PYRFU |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 2–678； UniProt 195–871 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 4doz |
| Deposition date deposition_date | 2012-02-12 |
| Structure title title | Crystal structure of Pyrococcus furiosus Cmr2 (Cas10) |
| Keywords keywords | Cyclase, CRISPR, Zn, ANTIVIRAL PROTEIN; ANTIVIRAL PROTEIN |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 27.86 Å |
| Rg (electron density) | 26.86 Å |
| Total Rg | 27.70 Å |
| Atom count | 4522 |
| Residues | 557 |
| Excluded volume | 81839 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d4doza1 |
| Class class | a — All alpha proteins |
| Fold Fold fold | a.24 — Four-helical up-and-down bundle |
| Superfamily Superfamily superfamily | a.24.30 — Helical bundle domains from Csm1/Cmr1-like |
| Family Family family | a.24.30.0 — automated matches |
| Domain ID domain_id | d4doza2 |
| Class class | d — Alpha and beta proteins (a+b) |
| Fold Fold fold | d.58 — Ferredoxin-like |
| Superfamily Superfamily superfamily | d.58.53 — Ferredoxin-like domains from CRISPR-associated proteins |
| Family Family family | d.58.53.7 — Nucleotide cyclase domains from Cmr2-like |
| Domain ID domain_id | d4doza3 |
| Class class | a — All alpha proteins |
| Fold Fold fold | a.24 — Four-helical up-and-down bundle |
| Superfamily Superfamily superfamily | a.24.30 — Helical bundle domains from Csm1/Cmr1-like |
| Family Family family | a.24.30.0 — automated matches |
| Domain ID domain_id | 4dozA01 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 30 — 2-Layer Sandwich |
| Topology topology | 70 — Alpha-Beta Plaits |
| Homologous superfamily homologous superfamily | 2220 — CRISPR-Cas system, Cmr2 subunit, D1 domain, cysteine cluster |
| Domain ID domain_id | 4dozA02 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 10 — Orthogonal Bundle |
| Topology topology | 10 — Arc Repressor Mutant, subunit A |
| Homologous superfamily homologous superfamily | 1720 — CRISPR-Cas system, Cmr2 subunit, D2 domain, helical bundle |
| Domain ID domain_id | 4dozA03 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 30 — 2-Layer Sandwich |
| Topology topology | 70 — Alpha-Beta Plaits |
| Homologous superfamily homologous superfamily | 270 — Reverse transcriptase/Diguanylate cyclase domain |
| Domain ID domain_id | 4dozA04 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 20 — Up-down Bundle |
| Topology topology | 120 — Four Helix Bundle (Hemerythrin (Met), subunit A) |
| Homologous superfamily homologous superfamily | 1260 — CRISPR-Cas system, Cmr2 subunit, D4 domain, six-helix bundle |