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4hqj

Crystal structure of Na+,K+-ATPase in the Na+-bound state

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Sodium/potassium-transporting ATPase subunit alpha-1

OrganismNot specified

UniProt P05024

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 Sodium/potassium-transporting ATPase subunit beta-1 × 1 （P05027） Na+/K+ ATPase gamma subunit transcript variant a × 1 （Q58K79） ADENOSINE-5'-DIPHOSPHATE × 1 TETRAFLUOROALUMINATE ION × 1 MAGNESIUM ION × 1 SODIUM ION × 3 CHOLESTEROL × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 Sodium/potassium-transporting ATPase subunit beta-1 × 1 （P05027） Na+/K+ ATPase gamma subunit transcript variant a × 1 （Q58K79） ADENOSINE-5'-DIPHOSPHATE × 1 TETRAFLUOROALUMINATE ION × 1 MAGNESIUM ION × 1 SODIUM ION × 3 CHOLESTEROL × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3b8e 3b8e 3kdp 3kdp 3n23 3n23 4hqj 4hqj 4hyt 4hyt 4res 4res

39 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name AT1A1_PIG
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–1021； UniProt 1–1021 Author chain C； PDBConstruct 1–1021； UniProt 1–1021

Sodium/potassium-transporting ATPase subunit beta-1

OrganismNot specified

UniProt P05027

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 Sodium/potassium-transporting ATPase subunit alpha-1 × 1 （P05024） Na+/K+ ATPase gamma subunit transcript variant a × 1 （Q58K79） ADENOSINE-5'-DIPHOSPHATE × 1 TETRAFLUOROALUMINATE ION × 1 MAGNESIUM ION × 1 SODIUM ION × 3 CHOLESTEROL × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 Sodium/potassium-transporting ATPase subunit alpha-1 × 1 （P05024） Na+/K+ ATPase gamma subunit transcript variant a × 1 （Q58K79） ADENOSINE-5'-DIPHOSPHATE × 1 TETRAFLUOROALUMINATE ION × 1 MAGNESIUM ION × 1 SODIUM ION × 3 CHOLESTEROL × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3b8e 3b8e 3kdp 3kdp 3n23 3n23 3wgu 3wgu 3wgv 3wgv 4hqj 4hqj

50 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name AT1B1_PIG
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–303； UniProt 1–303 Author chain D； PDBConstruct 1–303； UniProt 1–303

Na+/K+ ATPase gamma subunit transcript variant a

OrganismNot specified

UniProt Q58K79

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 Sodium/potassium-transporting ATPase subunit alpha-1 × 1 （P05024） Sodium/potassium-transporting ATPase subunit beta-1 × 1 （P05027） ADENOSINE-5'-DIPHOSPHATE × 1 TETRAFLUOROALUMINATE ION × 1 MAGNESIUM ION × 1 SODIUM ION × 3 CHOLESTEROL × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 Sodium/potassium-transporting ATPase subunit alpha-1 × 1 （P05024） Sodium/potassium-transporting ATPase subunit beta-1 × 1 （P05027） ADENOSINE-5'-DIPHOSPHATE × 1 TETRAFLUOROALUMINATE ION × 1 MAGNESIUM ION × 1 SODIUM ION × 3 CHOLESTEROL × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3b8e 3b8e 3kdp 3kdp 3n23 3n23 3wgu 3wgu 3wgv 3wgv 4hqj 4hqj

50 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name Q58K79_PIG
Isoform —
PDB entities 3
Chains and sequence ranges Author chain E； PDBConstruct 1–65； UniProt 1–65 Author chain G； PDBConstruct 1–65； UniProt 1–65

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id4hqj
Deposition date deposition_date2012-10-25
Structure title titleCrystal structure of Na+,K+-ATPase in the Na+-bound state
Keywords keywordsMembrane protein, Na+/K+ transport, HYDROLASE-TRANSPORT PROTEIN complex; HYDROLASE/TRANSPORT PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

4hqj__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

4hqj__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

4hqj__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）46.53 Å
Rg (electron density)46.82 Å
Total Rg46.59 Å
Atom count10251
Residues1297
Excluded volume184370 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 4hqj__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 4hqj__assembly_2__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (8)

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7. Citations (1)