4itv

Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, P212121 form

Method: X-RAY DIFFRACTION

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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Non-haem bromoperoxidase BPO-A2, Matrix protein 1

Influenza A virus

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	信息不足	同源多聚体	蛋白 12	无其他共同聚合物	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	M1_I34A1
Isoform	—
PDB实体	1
链与序列区间	作者链 A； PDB构建体 287–448； UniProt 3–164 作者链 B； PDB构建体 287–448； UniProt 3–164 作者链 C； PDB构建体 287–448； UniProt 3–164 作者链 D； PDB构建体 287–448； UniProt 3–164 作者链 E； PDB构建体 287–448； UniProt 3–164 作者链 F； PDB构建体 287–448； UniProt 3–164 作者链 G； PDB构建体 287–448； UniProt 3–164 作者链 H； PDB构建体 287–448； UniProt 3–164 作者链 I； PDB构建体 287–448； UniProt 3–164 作者链 J； PDB构建体 287–448； UniProt 3–164 作者链 K； PDB构建体 287–448； UniProt 3–164 作者链 L； PDB构建体 287–448； UniProt 3–164

Non-haem bromoperoxidase BPO-A2, Matrix protein 1

Influenza A virus

UniProt P29715

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	信息不足	同源多聚体	蛋白 12	无其他共同聚合物	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	BPOA2_STRAU
Isoform	—
PDB实体	1
链与序列区间	作者链 A； PDB构建体 1–278； UniProt 1–278 作者链 B； PDB构建体 1–278； UniProt 1–278 作者链 C； PDB构建体 1–278； UniProt 1–278 作者链 D； PDB构建体 1–278； UniProt 1–278 作者链 E； PDB构建体 1–278； UniProt 1–278 作者链 F； PDB构建体 1–278； UniProt 1–278 作者链 G； PDB构建体 1–278； UniProt 1–278 作者链 H； PDB构建体 1–278； UniProt 1–278 作者链 I； PDB构建体 1–278； UniProt 1–278 作者链 J； PDB构建体 1–278； UniProt 1–278 作者链 K； PDB构建体 1–278； UniProt 1–278 作者链 L； PDB构建体 1–278； UniProt 1–278

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id	4itv
沉积日期 deposition_date	2013-01-18
结构标题 title	Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, P212121 form
关键词 keywords	protein design, bionanotechnology, protein assembly, symmetric oligomeric domains, biomaterials, OXIDOREDUCTASE; OXIDOREDUCTASE
实验方法 method	X-RAY DIFFRACTION

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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

4itv__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

4itv__assembly_1__model_1 | I(q)

100 个绘图点；横轴和纵轴均采用对数尺度。

4itv__assembly_1__model_1 | P(r) · Pending

P(r) 将按相同 assembly/model 分别计算和展示。

Rg（Guinier）	58.99 Å
Rg（电子密度）	58.20 Å
总 Rg	58.20 Å
原子数	40776
残基数	5280
排除体积	724030 Å³
最大 q	0.500 Å⁻¹

Assembly	Model	结构单元	聚集说明	状态	CRYSOL	操作
1	1	`4itv__assembly_1__model_1`	dodecameric （12）	成功	4.1.3-1-20251215 (887e7ef)	查看下载

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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (1)

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6. 折叠分类 (SCOP + CATH) 36 domains

CATH v4.4 (36 domains)

结构域编号 domain_id	4itvA01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	4itvA02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	91 — Influenza Virus Matrix Protein; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — Influenza matrix M1, N-terminal subdomain 1

结构域编号 domain_id	4itvA03
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily	180 — Influenza matrix protein M1, N-terminal subdomain 2

结构域编号 domain_id	4itvB01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	4itvB02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	91 — Influenza Virus Matrix Protein; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — Influenza matrix M1, N-terminal subdomain 1

结构域编号 domain_id	4itvB03
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily	180 — Influenza matrix protein M1, N-terminal subdomain 2

结构域编号 domain_id	4itvC01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	4itvC02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	91 — Influenza Virus Matrix Protein; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — Influenza matrix M1, N-terminal subdomain 1

结构域编号 domain_id	4itvC03
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily	180 — Influenza matrix protein M1, N-terminal subdomain 2

结构域编号 domain_id	4itvD01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	4itvD02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	91 — Influenza Virus Matrix Protein; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — Influenza matrix M1, N-terminal subdomain 1

结构域编号 domain_id	4itvD03
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily	180 — Influenza matrix protein M1, N-terminal subdomain 2

结构域编号 domain_id	4itvE01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	4itvE02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	91 — Influenza Virus Matrix Protein; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — Influenza matrix M1, N-terminal subdomain 1

结构域编号 domain_id	4itvE03
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily	180 — Influenza matrix protein M1, N-terminal subdomain 2

结构域编号 domain_id	4itvF01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	4itvF02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	91 — Influenza Virus Matrix Protein; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — Influenza matrix M1, N-terminal subdomain 1

结构域编号 domain_id	4itvF03
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily	180 — Influenza matrix protein M1, N-terminal subdomain 2

结构域编号 domain_id	4itvG01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	4itvG02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	91 — Influenza Virus Matrix Protein; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — Influenza matrix M1, N-terminal subdomain 1

结构域编号 domain_id	4itvG03
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily	180 — Influenza matrix protein M1, N-terminal subdomain 2

结构域编号 domain_id	4itvH01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	4itvH02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	91 — Influenza Virus Matrix Protein; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — Influenza matrix M1, N-terminal subdomain 1

结构域编号 domain_id	4itvH03
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily	180 — Influenza matrix protein M1, N-terminal subdomain 2

结构域编号 domain_id	4itvI01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	4itvI02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	91 — Influenza Virus Matrix Protein; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — Influenza matrix M1, N-terminal subdomain 1

结构域编号 domain_id	4itvI03
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily	180 — Influenza matrix protein M1, N-terminal subdomain 2

结构域编号 domain_id	4itvJ01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	4itvJ02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	91 — Influenza Virus Matrix Protein; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — Influenza matrix M1, N-terminal subdomain 1

结构域编号 domain_id	4itvJ03
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily	180 — Influenza matrix protein M1, N-terminal subdomain 2

结构域编号 domain_id	4itvK01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	4itvK02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	91 — Influenza Virus Matrix Protein; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — Influenza matrix M1, N-terminal subdomain 1

结构域编号 domain_id	4itvK03
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily	180 — Influenza matrix protein M1, N-terminal subdomain 2

结构域编号 domain_id	4itvL01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	4itvL02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	91 — Influenza Virus Matrix Protein; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — Influenza matrix M1, N-terminal subdomain 1

结构域编号 domain_id	4itvL03
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily	180 — Influenza matrix protein M1, N-terminal subdomain 2

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晶胞边长 a length_a	131.620 Å
晶胞边长 b length_b	156.610 Å
晶胞边长 c length_c	321.150 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	90.00 °
晶胞夹角 γ angle_gamma	90.00 °
晶胞分子数 Z z_pdb	48

空间群 space_group	P 21 21 21
空间群编号 int_tables_number	19
晶系 crystal_system	—

分辨率 resolution	3.598 Å
最低分辨率 resolution_low	96.140 Å
R 因子 r_factor	0.2078
R_work r_work	0.2061
R_free r_free	0.2402

描述 description	Non-haem bromoperoxidase BPO-A2, Matrix protein 1
分子量 formula_weight	50281.4 kDa
EC 编号 ec_number	1.11.1.-
突变 mutation	K118A, L279Q, Q24T
来源方法 src_method	man
拷贝数 entity_count	12

聚合物类型 type	polypeptide(L)
链编号 strand_id	A,B,C,D,E,F,G,H,I,J,K,L
原子数 atom_count	40776

Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, P212121 form

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Non-haem bromoperoxidase BPO-A2, Matrix protein 1

当前结构中的状态

数据库中的同蛋白其他状态

Non-haem bromoperoxidase BPO-A2, Matrix protein 1

当前结构中的状态

数据库中的同蛋白其他状态

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

4itv__assembly_1__model_1

4itv__assembly_1__model_1 | I(q)

4itv__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (1)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

6. 折叠分类 (SCOP + CATH) 36 domains

CATH v4.4 (36 domains)

7. 引用文献 (1)

来源生物 organism	Influenza A virus
NCBI 分类编号 ncbi_taxonomy_id	211044
宿主生物 host_organism	Escherichia coli

Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, P212121 form

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Non-haem bromoperoxidase BPO-A2, Matrix protein 1

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

Non-haem bromoperoxidase BPO-A2, Matrix protein 1

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

4itv__assembly_1__model_1

4itv__assembly_1__model_1 | I(q)

4itv__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (1)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

6. 折叠分类 (SCOP + CATH) 36 domains

CATH v4.4 (36 domains)

7. 引用文献 (1)