4j6g

CRYSTAL STRUCTURE OF LIGHT AND DcR3 COMPLEX

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Tumor necrosis factor ligand superfamily member 14

Homo sapiens

UniProt O43557

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 其他组合 异源复合物 蛋白 12 其他聚合物 3 Tumor necrosis factor receptor superfamily member 6B × 6 (O95407) ;alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 CHLORIDE ION × 6 MAGNESIUM ION × 6 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 water × 12 与蛋白数一致
2 其他组合 异源复合物 蛋白 6 其他聚合物 3 Tumor necrosis factor receptor superfamily member 6B × 3 (O95407) ;alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 CHLORIDE ION × 3 MAGNESIUM ION × 3 water × 6 与蛋白数一致
3 蛋白异源复合物 异源复合物 蛋白 6 Tumor necrosis factor receptor superfamily member 6B × 3 (O95407) CHLORIDE ION × 3 MAGNESIUM ION × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 water × 6 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 TNF14_HUMAN
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 8–165; UniProt 83–240 作者链 B; PDB构建体 8–165; UniProt 83–240

Tumor necrosis factor receptor superfamily member 6B

Homo sapiens

UniProt O95407

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 其他组合 异源复合物 蛋白 12 其他聚合物 3 Tumor necrosis factor ligand superfamily member 14 × 6 (O43557) ;alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 CHLORIDE ION × 6 MAGNESIUM ION × 6 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 water × 12 与蛋白数一致
2 其他组合 异源复合物 蛋白 6 其他聚合物 3 Tumor necrosis factor ligand superfamily member 14 × 3 (O43557) ;alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 CHLORIDE ION × 3 MAGNESIUM ION × 3 water × 6 与蛋白数一致
3 蛋白异源复合物 异源复合物 蛋白 6 Tumor necrosis factor ligand superfamily member 14 × 3 (O43557) CHLORIDE ION × 3 MAGNESIUM ION × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 water × 6 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 TNF6B_HUMAN
Isoform —
PDB实体 2
链与序列区间 作者链 C; PDB构建体 1–166; UniProt 30–195 作者链 D; PDB构建体 1–166; UniProt 30–195

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id4j6g
沉积日期 deposition_date2013-02-11
结构标题 titleCRYSTAL STRUCTURE OF LIGHT AND DcR3 COMPLEX
关键词 keywords;LIGHT, DCR3, TNF, TNFR, TNF14, STRUCTURAL GENOMICS, PSI-BIOLOGY, NEW HVEM, N-GLYCOSYLATION, MEMBRANE, SECRETED PROTEIN, CYTOKINE, IFN, JELLY-ROLL FOLD, BIND TNF RECEPTOR HVEM AND LTBR, LTBR, Protein Structure Initiative, Atoms-to-Animals: The Immune Function Network, New York Structural Genomics Research Consortium, NYSGRC, IMMUNE SYSTEM ;; IMMUNE SYSTEM
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

4j6g__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

4j6g__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

4j6g__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)41.19 Å
Rg(电子密度)40.89 Å
总 Rg41.22 Å
原子数14016
残基数1809
排除体积245470 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 4j6g__assembly_1__model_1 dodecameric (12) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
2 1 4j6g__assembly_2__model_1 hexameric (6) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
3 1 4j6g__assembly_3__model_1 hexameric (6) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (7)

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6. 折叠分类 (SCOP + CATH) 8 domains

SCOP 2.08 (2 domains)

结构域编号 domain_idd4j6ga_
类 Class classb — All beta proteins
折叠类型 Fold foldb.22 — TNF-like
超家族 Superfamily superfamilyb.22.1 — TNF-like
家族 Family familyb.22.1.0 — automated matches
结构域编号 domain_idd4j6gb_
类 Class classb — All beta proteins
折叠类型 Fold foldb.22 — TNF-like
超家族 Superfamily superfamilyb.22.1 — TNF-like
家族 Family familyb.22.1.0 — automated matches

CATH v4.4 (6 domains)

结构域编号 domain_id4j6gA00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily40 —
结构域编号 domain_id4j6gB00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily40 —
结构域编号 domain_id4j6gC01
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology50 — Tumor Necrosis Factor Receptor, subunit A; domain 2
同源超家族 H-superfamily homologous superfamily10 — Tumor Necrosis Factor Receptor, subunit A, domain 2
结构域编号 domain_id4j6gC02
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology50 — Tumor Necrosis Factor Receptor, subunit A; domain 2
同源超家族 H-superfamily homologous superfamily10 — Tumor Necrosis Factor Receptor, subunit A, domain 2
结构域编号 domain_id4j6gD01
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology50 — Tumor Necrosis Factor Receptor, subunit A; domain 2
同源超家族 H-superfamily homologous superfamily10 — Tumor Necrosis Factor Receptor, subunit A, domain 2
结构域编号 domain_id4j6gD02
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology50 — Tumor Necrosis Factor Receptor, subunit A; domain 2
同源超家族 H-superfamily homologous superfamily10 — Tumor Necrosis Factor Receptor, subunit A, domain 2
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7. 引用文献 (1)