Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白同源多聚体 | 同源多聚体 | 蛋白 4 | CYCLIC GUANOSINE MONOPHOSPHATE × 8 ACETATE ION × 4 GLYCEROL × 2 water × 4 | 与蛋白数一致 |
| UniProt名称 | HCN4_HUMAN |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 7–199； UniProt 521–713 作者链 B； PDB构建体 7–199； UniProt 521–713 作者链 C； PDB构建体 7–199； UniProt 521–713 作者链 D； PDB构建体 7–199； UniProt 521–713 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 4kl1 |
| 沉积日期 deposition_date | 2013-05-07 |
| 结构标题 title | HCN4 CNBD in complex with cGMP |
| 关键词 keywords | ;CNBD, cAMP, cGMP, c-di-GMP, c-di-AMP, ion channel, HCN, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel, cAMP binding, cGMP binding, PROTEIN TRANSPORT ;; PROTEIN TRANSPORT |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 30.65 Å |
| Rg（电子密度） | 29.57 Å |
| 总 Rg | 30.41 Å |
| 原子数 | 6620 |
| 残基数 | 768 |
| 排除体积 | 116600 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d4kl1a_ |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.82 — Double-stranded beta-helix |
| 超家族 Superfamily superfamily | b.82.3 — cAMP-binding domain-like |
| 家族 Family family | b.82.3.2 — cAMP-binding domain |
| 结构域编号 domain_id | d4kl1b_ |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.82 — Double-stranded beta-helix |
| 超家族 Superfamily superfamily | b.82.3 — cAMP-binding domain-like |
| 家族 Family family | b.82.3.2 — cAMP-binding domain |
| 结构域编号 domain_id | d4kl1c_ |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.82 — Double-stranded beta-helix |
| 超家族 Superfamily superfamily | b.82.3 — cAMP-binding domain-like |
| 家族 Family family | b.82.3.2 — cAMP-binding domain |
| 结构域编号 domain_id | d4kl1d_ |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.82 — Double-stranded beta-helix |
| 超家族 Superfamily superfamily | b.82.3 — cAMP-binding domain-like |
| 家族 Family family | b.82.3.2 — cAMP-binding domain |
| 结构域编号 domain_id | 4kl1A01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 287 — Helix Hairpins |
| 同源超家族 H-superfamily homologous superfamily | 630 — Helix hairpin bin |
| 结构域编号 domain_id | 4kl1A02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 60 — Sandwich |
| 拓扑 Topology topology | 120 — Jelly Rolls |
| 同源超家族 H-superfamily homologous superfamily | 10 — Jelly Rolls |
| 结构域编号 domain_id | 4kl1B01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 287 — Helix Hairpins |
| 同源超家族 H-superfamily homologous superfamily | 630 — Helix hairpin bin |
| 结构域编号 domain_id | 4kl1B02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 60 — Sandwich |
| 拓扑 Topology topology | 120 — Jelly Rolls |
| 同源超家族 H-superfamily homologous superfamily | 10 — Jelly Rolls |
| 结构域编号 domain_id | 4kl1C01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 287 — Helix Hairpins |
| 同源超家族 H-superfamily homologous superfamily | 630 — Helix hairpin bin |
| 结构域编号 domain_id | 4kl1C02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 60 — Sandwich |
| 拓扑 Topology topology | 120 — Jelly Rolls |
| 同源超家族 H-superfamily homologous superfamily | 10 — Jelly Rolls |
| 结构域编号 domain_id | 4kl1D01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 287 — Helix Hairpins |
| 同源超家族 H-superfamily homologous superfamily | 630 — Helix hairpin bin |
| 结构域编号 domain_id | 4kl1D02 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 60 — Sandwich |
| 拓扑 Topology topology | 120 — Jelly Rolls |
| 同源超家族 H-superfamily homologous superfamily | 10 — Jelly Rolls |