4ldd

Crystal Structure of Ebola virus VP40 Hexamer

Method: X-RAY DIFFRACTION

1. Protein Identity and Related Structures Protein Identity & Related Structures

Matrix protein VP40

Ebola virus

UniProt Q05128

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 6 No other associated polymer Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name VP40_EBOZM
Isoform
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 15–297; UniProt 44–326 Author chain B; PDBConstruct 15–297; UniProt 44–326 Author chain C; PDBConstruct 15–297; UniProt 44–326

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

2. Structure Basics 2. Structure Basics

Entry ID entry_id4ldd
Deposition date deposition_date2013-06-24
Structure title titleCrystal Structure of Ebola virus VP40 Hexamer
Keywords keywordsebolavirus matrix assembly, VIRAL PROTEIN; VIRAL PROTEIN
Experimental Method methodX-RAY DIFFRACTION

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

4ldd__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

4ldd__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

4ldd__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)41.38 Å
Rg (electron density)42.21 Å
Total Rg42.37 Å
Atom count7766
Residues1004
Excluded volume140980 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 4ldd__assembly_1__model_1 hexameric (6) Success 4.1.3-1-20251215 (887e7ef) View Download

4. Crystallography and Experiment 4. Crystallography & Experiment

5. Entities and Polymers Entities & Polymers (1)

6. Fold Classification (SCOP + CATH) 4 domains

CATH v4.4 (4 domains)

Domain ID domain_id4lddA00
Class class2 — Mainly Beta
Architecture architecture70 — Distorted Sandwich
Topology topology20 — Topoisomerase I; domain 3
Homologous superfamily homologous superfamily20 — Matrix protein VP40, N-terminal domain
Domain ID domain_id4lddB01
Class class2 — Mainly Beta
Architecture architecture70 — Distorted Sandwich
Topology topology20 — Topoisomerase I; domain 3
Homologous superfamily homologous superfamily20 — Matrix protein VP40, N-terminal domain
Domain ID domain_id4lddB02
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology510 — EV matrix protein fold
Homologous superfamily homologous superfamily10 — EV matrix protein
Domain ID domain_id4lddC00
Class class2 — Mainly Beta
Architecture architecture70 — Distorted Sandwich
Topology topology20 — Topoisomerase I; domain 3
Homologous superfamily homologous superfamily20 — Matrix protein VP40, N-terminal domain

7. Citations (1)