Escherichia coli
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白单体 | 单体 | 蛋白 1 | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER × 1 CALCIUM ION × 3 2-amino-8-{[2-(3-methylphenyl)-2-oxoethyl]sulfanyl}-1,9-dihydro-6H-purin-6-one × 1 GLYCEROL × 1 water × 1 | 与蛋白数一致 |
| UniProt名称 | HPPK_ECOLI |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 4–162； UniProt 1–159 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 4m5k |
| 沉积日期 deposition_date | 2013-08-08 |
| 结构标题 title | The Identification, Analysis and Structure-Based Development of Novel Inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase |
| 关键词 keywords | FOLATE BIOSYNTHESIS, Diphosphotransferases, PTERIN, ATP binding, Inhibitor, TRANSFERASE-TRANSFERASE INHIBITOR complex; TRANSFERASE/TRANSFERASE INHIBITOR |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 16.04 Å |
| Rg（电子密度） | 14.86 Å |
| 总 Rg | 15.92 Å |
| 原子数 | 1337 |
| 残基数 | 159 |
| 排除体积 | 23827 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d4m5ka_ |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.58 — Ferredoxin-like |
| 超家族 Superfamily superfamily | d.58.30 — 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK |
| 家族 Family family | d.58.30.1 — 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK |
| 结构域编号 domain_id | 4m5kA00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 70 — Alpha-Beta Plaits |
| 同源超家族 H-superfamily homologous superfamily | 560 — 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK |